Tamtam Start free

The 30 largest companies with in-house R&D in Madrid

Tamtam tracks 158 companies with in-house R&D headquartered in Madrid. This list ranks the 30 largest by number of employees on LinkedIn, led by Telefónica, Quirónsalud and Indra Group. Their median headcount is 8,620. Half of them were founded in 1968 or later.

🇪🇸 Madrid30 companiesUpdated Nov 11, 2026

This selection of Madrid companies with in-house R&D includes large corporations and established firms across diverse sectors. Key players include Telefónica, a global telecommunications company; Quirónsalud, a leader in healthcare; Indra Group, focused on defense, space, and IT solutions; and ACCIONA, specializing in regenerative infrastructure. NTT DATA Europe & Latam provides global IT services, while Repsol is prominent in oil and gas.

The data reveals a strong concentration of headquarters in Madrid, indicating the city's role as a central hub for these large entities. The companies span industries such as telecommunications, healthcare, defense, utilities, IT services, and energy, reflecting a broad spectrum of technological and industrial development within the capital.

#CompanyIndustryHeadquarters EmployeesFounded
1
Telefónicatelefonica.com

Leading global telecommunications company providing advanced infrastructure, innovative digital and data services, focusing on secure, cutting-edge technology and social impact.

Telecommunications 🇪🇸 Madrid 121,569 n/a
2
Quirónsaludquironsalud.com

Leader in healthcare in Spain and Europe with over 50,000 professionals and 59 hospitals, focusing on medical research, education, and cutting-edge technology

Wellness and Fitness Services 🇪🇸 Madrid 50,000 1893
3
Indra Groupindragroup.com

Leading multinational providing defense, space, air traffic management, and mobility solutions alongside information technology services, artificial intelligence, cybersecurity, and advanced digital transformation projects.

Defense and Space Manufacturing 🇪🇸 Madrid 39,308 n/a
4
ACCIONAacciona.com

The company specializes in developing regenerative infrastructure with a focus on sustainability, leading the transition to a low-carbon economy with a positive impact on people and the planet

Utilities 🇪🇸 Madrid 33,828 n/a
5
NTT DATA Europe & Latamnttdata.com

Global IT services provider transforming clients through consulting, solutions, and managed services to enable a confident move into the digital future

IT Services and IT Consulting 🇪🇸 Madrid 31,932 n/a
6
repsolrepsol.com

A leading player in the oil and gas industry, involved in exploration, production, transformation, development, and marketing of efficient, sustainable energy solutions globally

Oil and Gas 🇪🇸 Madrid 26,030 n/a
7
Amadeusamadeus.com

A company revolutionizing the travel industry by inspiring innovation, partnerships, and responsibility, connecting the travel ecosystem and promoting social and environmental good

IT Services and IT Consulting 🇪🇸 Madrid 23,625 1987
8
Applus+applus.com

A global leader in testing, inspection, and certification services, providing innovative solutions for asset integrity, regulatory compliance, and environmental performance

Business Consulting and Services 🇪🇸 Madrid 20,046 n/a
9
Gestampgestamp.com

A multinational company specializing in designing and manufacturing advanced metal components for vehicle manufacturers worldwide, focusing on lighter, safer, and more environmentally friendly products

Motor Vehicle Manufacturing 🇪🇸 Madrid 17,667 1997
10
Universidad Complutense de Madriducm.es

A public university in Madrid offering high-quality education, research opportunities, international collaborations, extensive library resources, diverse cultural activities, and sports facilities

Higher Education 🇪🇸 Madrid 14,024 1499
11
Universidad Autónoma de Madriduam.es

Institution recognized for high-quality research, entrepreneurial capacity, teaching excellence, and social commitment. Actively promotes international exchange and training programs.

Higher Education 🇪🇸 Madrid 14,000 1968
12
Tecnicas Reunidastecnicasreunidas.es

An international general contractor specializing in engineering and construction of industrial facilities in oil & gas, refining, power generation, infrastructures, and energy transition

Engineering Services 🇪🇸 Madrid 12,368 1960
13
Grupo Tragsatragsa.es

Provides engineering, technical assistance, and execution of projects for public administrations in agriculture, environment, and rural development sectors.

Environmental Services 🇪🇸 Madrid 12,239 1977
14
Elecnor Groupgrupoelecnor.com

Global corporation specializing in engineering, construction, sustainable projects, infrastructure investments, renewable energy, asset management, and energy transmission across 50 countries.

Construction 🇪🇸 Madrid 10,383 1958
15
NINGUNOsiadde.es

A technology company with over 20 years of experience providing comprehensive solutions in security systems, telecommunications, software development, and more for various industries

Telecommunications 🇪🇸 Madrid 8,620 2026

Want more companies than this list?

This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers.

Get more companies, free
16
Insud Pharmainsudpharma.com

Specialized pharmaceutical company with global presence, offering APIs, finished dosage forms, branded medicines, and biotech solutions for human and animal health.

Pharmaceutical Manufacturing 🇪🇸 Madrid 7,035 1977
17
INECOineco.com

A leading engineering and consulting firm in sustainable mobility and digital transformation, with a global presence and a focus on innovation

Civil Engineering 🇪🇸 Madrid 5,743 1968
18
Management Solutionsmanagementsolutions.com

Providing consulting services in strategy, organization, risk management, and technology for financial, energy, and telecommunications sectors worldwide.

Business Consulting and Services 🇪🇸 Madrid 4,798 2002
19
OHLA Groupohla-group.com

A global leader in construction, engineering, and development projects, focusing on transport infrastructure, unique buildings, and sustainable progress in various regions worldwide

Construction 🇪🇸 Madrid 4,270 1911
20
GRI RENEWABLE INDUSTRIES SLgri.com.es

Manufactures towers and flanges for the wind energy sector globally, including onshore and offshore towers, wind flanges, and wind castings components.

Semiconductor Manufacturing 🇪🇸 Madrid 4,000 2008
21
HM Hospitaleshmhospitales.com

Private healthcare group with 54 centers offering specialized hospitals, clinics, and integrated care focused on quality, innovation, and patient wellbeing.

Wellness and Fitness Services 🇪🇸 Madrid 3,803 1989
22
Hospital Universitario La Pazcomunidad.madrid

A public hospital in Madrid that offers specialized healthcare services to patients from Spain and other countries, with a strong reputation in the healthcare industry

Hospitals and Health Care 🇪🇸 Madrid 3,225 1964
23
Hospital Gregorio Marañónhggm.es

A public hospital in Madrid known for highly trained professionals, teaching and research, technological advancements, and national/international specialty care

Medical Practices 🇪🇸 Madrid 3,146 n/a
24
Fundación Hospitalariasfundacionhospitalarias.org

Non-profit institution providing specialized care, assistance, and social reintegration for individuals with mental illness, intellectual disabilities, and other conditions worldwide

Hospitals and Health Care 🇪🇸 Madrid 3,112 1881
25
Navantianavantia.es

Civil and military shipbuilding, ship repairs, turbine manufacturing, engine production, and weapon systems development with centuries of experience.

Shipbuilding 🇪🇸 Madrid 2,977 n/a
26
Universidad Pontificia Comillascomillas.edu

A long-standing university with Jesuit leadership, emphasizing tradition, modern education, and strong connections with business, professional, and social sectors

Higher Education 🇪🇸 Madrid 2,920 1890
27
Exeltisexeltis.com

Innovative global organization in the pharmaceutical sector, committed to improving health through the development and marketing of medicinal products worldwide

Pharmaceutical Manufacturing 🇪🇸 Madrid 2,659 2003
28
Banco de Españabde.es

National central bank and banking supervisor, managing monetary policy, currency issuance, payment systems, and financial system stability in Spain.

Banking 🇪🇸 Madrid 2,585 1782
29
Chemochemopharmaceuticals.com

Specializing in pharmaceutical research, development, manufacturing, and sales worldwide, with a focus on innovation and sustainable development to improve health and quality of life

Pharmaceutical Manufacturing 🇪🇸 Madrid 2,388 1977
30
Nippon Sanso Europenippongases.com

A leading European company in industrial and medical gases, offering innovative solutions for various industries, prioritizing safety, quality, and sustainability

Chemical Manufacturing 🇪🇸 Madrid 2,106 n/a

Turn this list into pipeline

Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.

Build your own list, free

How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

More company lists in Madrid

The same list elsewhere in Spain