The largest multinational companies in Delaware are primarily engaged in manufacturing, particularly chemical manufacturing, and financial services. Among these, DuPont is a global company focused on essential innovations, while Solenis specializes in sustainable solutions for water-intensive industries. W. L. Gore & Associates is a materials science company solving technical challenges, and CSC provides global business administration and compliance solutions.
A notable characteristic of these companies is their long-standing presence, with several founded in the early 20th century, such as Solenis (1907), Ashland (1924), and Wilmington Trust (1903). The concentration of headquarters in Wilmington is also significant, indicating a central hub for these multinational operations within the state.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
DuPontdupont.com
A global company focused on creating essential innovations, uncovering insights, and inventing a better now for a brighter future |
22,104 | |||
| 2 |
Solenissolenis.com
A global specialty chemicals producer offering sustainable solutions for water-intensive industries with a wide range of products and technologies for improving operational efficiency and environmental impact |
21,407 | |||
| 3 |
W. L. Gore & Associatesgore.com
A global materials science company solving technical challenges in diverse environments, generating annual revenues of $48 billion, and improving lives |
10,358 | |||
| 4 |
CSCcscglobal.com
Global business administration and compliance solutions for alternative asset managers, capital markets, digital brand protection, domain management, and corporate tax software services. |
8,233 | |||
| 5 | 6,095 | ||||
| 6 |
Ashlandashland.com
This company provides additives and specialty ingredients to various consumer and industrial markets globally, focusing on innovative solutions for complex customer problems. |
5,843 | |||
| 7 | 4,635 | ||||
| 8 |
The Chemours Companychemours.com
A company driven by chemistry, providing sustainable solutions for various industries like automotive, electronics, energy, and construction through Courageous Chemistry™ |
4,528 | |||
| 9 |
Enovisenovis.com
A medical technology company creating innovative solutions for better patient outcomes, improved workflows, and active lifestyles through collaboration with healthcare professionals |
3,892 | |||
| 10 |
Incyteincyte.com
Global biopharmaceutical company focused on discovering, developing, and commercializing innovative medicines for patients with unmet medical needs in Oncology and Inflammation & Autoimmunity. |
3,425 | |||
| 11 |
Wilmington Trustwilmingtontrust.com
The company provides wealth management, global capital markets, and institutional retirement services with a focus on client relationships, innovation, and trust |
2,074 | |||
| 12 |
Emerging Travel Groupemergingtravel.com
A pioneering travel-tech company offering a vast selection of accommodations worldwide, with a diverse team dedicated to simplifying and enhancing the travel experience for all |
1,713 | |||
| 13 |
EDBenterprisedb.com
A global provider of enterprise-class software and services for harnessing the power of Postgres, offering high availability, reliability, security, and 24x7 support |
1,534 | |||
| 14 | 1,255 | ||||
| 15 | 1,032 | ||||
| 16 |
LabWarelabware.com
Global leader in enterprise-scale laboratory automation solutions, offering integrated LIMS, ELN, LES, method execution, SDMS, and data analytics for optimized compliance and productivity |
1,030 | |||
| 17 |
Chem-Aqua, Inc.chemaqua.com
A leading provider of custom water treatment solutions for boiler, cooling, and process water systems, focusing on energy efficiency and cost savings |
950 | |||
| 18 |
Soul AIdeccanexperts.ai
An Enterprise AI firm providing RLHF and Custom AI solutions, led by an experienced team, prioritizing employee wellness and offering remote AI trainer opportunities |
852 | |||
| 19 | 768 | ||||
| 20 |
Codingalcodingal.com
Provides online AI and coding education for kids and teens, offering live, interactive classes and personalized learning paths for future tech leaders. |
763 | |||
| 21 |
The LYCRA Companylycra.com
Innovates and produces fiber and technology solutions for global apparel and hygiene industries, focusing on comfort and lasting performance benefits for clothing across many categories. |
611 | |||
| 22 | 725 | ||||
| 23 |
QPS Holdings, LLCqps.com
A global contract research organization specializing in discovery, preclinical, and clinical drug development services with a focus on bioanalytics and clinical trials |
719 | |||
| 24 |
DuPont™ Spectrum™spectrumplastics.com
Leading partner in developing and manufacturing critical polymer-based components and finished devices for medical and demanding applications. |
704 | |||
| 25 |
EvonSysevonsys.com
Industry leaders with decades of experience delivering digital transformation solutions globally, specializing in BPM implementations across various sectors with development centers worldwide |
701 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 26 |
OWASP® Foundationowasp.org
Worldwide free open community improves software security, making application security visible for informed decisions regarding application security risks. |
683 | |||
| 27 |
Bel Fuse Inc.belfuse.com
Designs, manufactures, and markets products for powering, protecting, and connecting electronic circuits. A global supplier with technical innovation and cost-effective solutions. |
676 | |||
| 28 |
TekisHub Consulting Servicestekishub.com
Staff augmentation, software development, and recruitment process outsourcing company providing multi-platform application solutions globally from USA and India Specializing in high-quality service and cost-effective solutions |
658 | |||
| 29 |
TA Instrumentstainstruments.com
Develops and supplies instruments for material characterization, including thermal analysis, rheology, and microcalorimetry, used for research, analysis, and quality control. |
655 | |||
| 30 |
Datavalley Incdatavalley.ai
A leading provider of training and consulting services in Big Data, Data Science, DevOps, IoT, and Cloud Technologies, delivering innovative data solutions tailored to clients' needs |
618 | |||
| 31 |
Solution Analystssolutionanalysts.com
A global enterprise software development company specializing in mobile, web, and IoT solutions, leveraging AI, AR, VR, and blockchain technologies for client success |
608 | |||
| 32 |
Rain Carbon Incraincarbon.com
Global producer of carbon-based products and advanced materials, transforming byproducts into high-value products for industrial processes and manufactured goods worldwide |
575 | |||
| 33 |
DuPont Water Solutionsdupont.com
The company provides solutions for a sustainable energy and water future globally, assisting businesses in making real progress in every industry |
558 | |||
| 34 |
Careermindscareerminds.com
This company offers outplacement, executive coaching, and career development services globally in multiple languages using technology and personalized coaching |
552 | |||
| 35 |
RateHawkratehawk.com
An innovative B2B online booking engine offering hotels, air tickets, transfers, and car hire globally with a focus on customer satisfaction and competitive pricing |
540 | |||
| 36 | 511 | ||||
| 37 |
Seacretseacret.com
This company manufactures skincare products using minerals and salts from the Dead Sea, focusing on purity, effectiveness, and ethical practices |
482 | |||
| 38 |
Tessituratessitura.com
Nonprofit technology company providing CRM platform and support to over 800 arts and cultural organizations across ten countries. |
474 | |||
| 39 |
Velan Info Servicesvelaninfo.com
A global provider offering 24x7 operations for services like data processing, customer support, bookkeeping, IT infrastructure, and more, striving for professionalism and perfectionism Contact +1-860-215-4997 |
465 | |||
| 40 |
VLMS Global (Valiant LifeCare Medical Solutions)vlmshealthcare.com
A global healthcare services company specializing in medical coding, data abstraction, and standardizing data procedures for improved insights and reporting |
424 | |||
| 41 |
KPL Tech Solution Pvt. Ltd.kpltechsolution.com
A team of SEO experts at KPL Tech Solution helps businesses grow online with tailored marketing strategies, packages, services, and approaches |
412 | |||
| 42 |
Thinkitive Inc.thinkitive.com
A global technology and solution provider specializing in Healthcare, Retail, and Technology services, offering end-to-end software development and integration solutions worldwide |
409 | |||
| 43 |
MSRcosmos LLCmsrcosmos.com
Global technology company specializing in AI, cloud, data analytics, automation, and enterprise applications to drive digital transformation for businesses. |
397 | |||
| 44 |
Airaloairalo.com
Providing pain-free connectivity for travelers worldwide with over 200 affordable eSIM options, eliminating the need for multiple SIM cards |
390 | |||
| 45 |
Escalon Servicesescalon.services
Outsourced finance, accounting, tax, HR, and insurance services for startups, SMBs, and non-profits to simplify back-office operations. |
358 | |||
| 46 |
Vizva Consultancy Servicesvizvaconsultancyservices.com
Connecting people with opportunities to help businesses succeed and careers flourish, promoting united growth without inequity Stand for "entire world" in Sanskrit |
355 | |||
| 47 |
Xevyte Technologiesxevyte.com
An IT technology provider offering tailored solutions for businesses, guiding them through challenges and helping them succeed in the digital era |
354 | |||
| 48 | 353 | ||||
| 49 |
Global Peace Chainglobalpeacechain.org
Cultivates tolerance, inclusivity, and social peacebuilding globally through peace camps, discussions with stakeholders, and community engagement via ambassadors. |
351 | |||
| 50 |
TT Consultantsttconsultants.com
A global leader in IP, technology intelligence, business research, and innovation support blending AI and human expertise for clients worldwide |
348 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
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The same list elsewhere in United States
- Multinational companies in the United States 16,197
- Multinational companies in California 2,592
- Multinational companies in New York State 2,216
- Multinational companies in Texas 1,418
- Multinational companies in Florida 897
- Multinational companies in Illinois 831
- Multinational companies in Massachusetts 637
- Multinational companies in New Jersey 624
- Multinational companies in Georgia 521
- Multinational companies in Pennsylvania 472
- Multinational companies in Michigan 468
- Multinational companies in Alabama 416
- Multinational companies in Virginia 396
- Multinational companies in Ohio 390
- Multinational companies in North Carolina 358
- Multinational companies in Washington State 288
- Multinational companies in Colorado 228
- Multinational companies in New York 1,836
- Multinational companies in San Francisco 446
- Multinational companies in Houston 402
- Multinational companies in Chicago 366
- Multinational companies in Miami 289
- Multinational companies in Atlanta 252
- Multinational companies in Boston 241