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The 50 largest pharmaceutical companies in Spain

Tamtam tracks 127 pharmaceutical companies headquartered in Spain. This list ranks the 50 largest by number of employees on LinkedIn, led by Grifols, Insud Pharma and Werfen. Their median headcount is 806. Half of them were founded in 1963 or later. The most common headquarters are Barcelona (13), Madrid (10) and Sant Cugat del Vallès (3).

🇪🇸 Spain50 companiesUpdated Nov 12, 2026

The companies listed here are primarily large pharmaceutical manufacturing firms operating in Spain, many with a global presence. They specialize in developing and marketing a wide range of medicinal products, from plasma-derived medicines and APIs to dermatology solutions and animal health vaccines. Examples include Grifols, a global healthcare company specializing in plasma-derived medicines; Insud Pharma, focused on APIs and biotech solutions; and Almirall, a biopharmaceutical company in medical dermatology.

Most of these companies are well-established, with several founded in the early to mid-20th century, such as Grifols (1909), Laboratorios Normon (1937), and ESTEVE (1929). A notable pattern is the concentration of headquarters in the Madrid and Barcelona areas, indicating key hubs for the pharmaceutical industry in Spain. While the majority are pharmaceutical manufacturers, Werfen stands out as a medical equipment manufacturer, and TRADEBE provides environmental services.

#CompanyIndustryHeadquarters EmployeesFounded
1
Grifolslinktr.ee

A global healthcare company specializing in plasma-derived medicines, transfusion medicine, and innovative healthcare solutions, committed to improving people's health worldwide

Pharmaceutical Manufacturing 🇪🇸 Sant Cugat del Vallès 14,329 1909
2
Insud Pharmainsudpharma.com

Specialized pharmaceutical company with global presence, offering APIs, finished dosage forms, branded medicines, and biotech solutions for human and animal health.

Pharmaceutical Manufacturing 🇪🇸 Madrid 7,035 1977
3
Werfenwerfen.com

A global innovator in specialized diagnostics, offering Hemostasis, Acute Care Diagnostics, Transfusion, Autoimmunity, and Transplant solutions through OEM manufacturing and distribution

Medical Equipment Manufacturing 🇪🇸 L'Hospitalet de Llobregat 6,858 n/a
4
Exeltisexeltis.com

Innovative global organization in the pharmaceutical sector, committed to improving health through the development and marketing of medicinal products worldwide

Pharmaceutical Manufacturing 🇪🇸 Madrid 2,659 2003
5
Laboratorios Normonnormon.com

A Spanish pharmaceutical laboratory with over 85 years of experience specializing in high-quality medicines, offering a wide range of products internationally

Pharmaceutical Manufacturing 🇪🇸 Tres Cantos 2,427 1937
6
Almirallalmirall.com

Global biopharmaceutical company focused on medical dermatology, developing innovative solutions for dermatological diseases through R&D, healthcare partnerships, and global presence in 100+ countries

Pharmaceutical Manufacturing 🇪🇸 Barcelona 2,401 n/a
7
Chemochemopharmaceuticals.com

Specializing in pharmaceutical research, development, manufacturing, and sales worldwide, with a focus on innovation and sustainable development to improve health and quality of life

Pharmaceutical Manufacturing 🇪🇸 Madrid 2,388 1977
8
ESTEVEesteve.com

International pharmaceutical company focused on improving people's lives through innovative solutions and environmentally sustainable practices, with production sites globally

Pharmaceutical Manufacturing 🇪🇸 Barcelona 2,305 1929
9
ISDINisdin.com

International pharmaceutical company specializing in dermatology solutions, providing treatments, prevention and maintenance for skin conditions worldwide through research and innovation

Pharmaceutical Manufacturing 🇪🇸 Barcelona 2,172 1975
10
Ferrerferrer.com

The company advocates for social justice through business initiatives and projects

Pharmaceutical Manufacturing 🇪🇸 Barcelona 2,171 1959
11
HIPRAhipra.com

Biotechnological pharmaceutical company specializing in innovative vaccines and diagnostic services for animal and human health worldwide

Pharmaceutical Manufacturing 🇪🇸 Amer 2,113 n/a
12
TRADEBEtradebe.com

A global business group focused on environmental services, life sciences, health & nutrition, and port services with over 100 sites worldwide

Environmental Services 🇪🇸 Barcelona 2,111 1983
13
FAES FARMAfaesfarma.com

A Spanish pharmaceutical company with international presence, Faes Farma conducts research, produces, and markets pharmaceutical products and raw materials, exporting globally

Pharmaceutical Manufacturing 🇪🇸 Vizcaya 1,519 1933
14
Grupo Indukerngrupoindukern.com

The Indukern Group consists of companies involved in chemical product distribution, veterinary products, and generic pharmaceuticals, with a sales volume of around 600 million Euros

Pharmaceutical Manufacturing 🇪🇸 Terrassa 1,327 1962
15
ROVI Pharmaceutical Companyrovi.es

Chemical and pharmaceutical company focused on own products, third-party manufacturing, and licensed product distribution to promote health globally.

Pharmaceutical Manufacturing 🇪🇸 Madrid 1,273 1946
16
Italfarmacoitalfarmaco.es

Italian pharmaceutical group founded in 1938, operating in pharmaceutical and fine chemical industries Markets ethical products in Southern Europe with high therapeutic content

Pharmaceutical Manufacturing 🇪🇸 Alcobendas 1,254 1991
17
mAbxiencemabxience.com

A Spanish company specializing in developing, producing, and selling biopharmaceuticals globally They provide affordable medicines and offer Contract Development and Manufacturing Organization services

Pharmaceutical Manufacturing 🇪🇸 Madrid 1,209 2009
18
CINFAcinfa.com

A Spanish laboratory in Navarra with a focus on providing quality and accessible healthcare solutions, emphasizing prevention and improving quality of life

Pharmaceutical Manufacturing 🇪🇸 Olloki 1,078 1969
19
Cantabria Labscantabrialabs.es

A leading European dermatological prescription brand focused on improving health with innovative products, international presence, and high-quality manufacturing standards

Pharmaceutical Manufacturing 🇪🇸 Calle Arequipa 1,017 n/a
20
Grupo Altergrupoalter.es

A healthcare company focused on innovation, quality, and service, distributing products globally and fostering a strong team through continuous training and support

Pharmaceutical Manufacturing 🇪🇸 Madrid 954 1940
21
Neuraxpharmneuraxpharm.com

A European specialty pharmaceutical company focusing on treating central nervous system disorders, with a strong presence in over 20 European countries

Pharmaceutical Manufacturing 🇪🇸 Sant Joan Despí 921 n/a
22
Uriachuriach.com

Development and marketing of natural consumer healthcare products with scientific innovation, strong European presence, and expanding global distribution network.

Pharmaceutical Manufacturing 🇪🇸 Sant Cugat del Vallès 912 1838
23
Kern Pharmakernpharma.com

Pharmaceutical company within Indukern Group specializing in generic, ethical, and hospital products Offers contract manufacturing services for pharmaceutical market leaders

Pharmaceutical Manufacturing 🇪🇸 Terrassa 909 1999
24
Reig Jofrereigjofre.com

A pharma company focused on research, development, and marketing of medicines, food supplements, and specialized manufacturing for third parties

Pharmaceutical Manufacturing 🇪🇸 Sant Joan Despi 884 1929
25
ROVI Pharma Industrial Servicesroviservices.com

Specializing in aseptic fill-finish for injectables, ROVI offers manufacturing and packaging solutions for vaccines, biologics, and other pharmaceutical products worldwide

Pharmaceutical Manufacturing 🇪🇸 Madrid 806 1946

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26
Galenicumgalenicum.com

A Barcelona-based company improving pharmaceutical quality and affordability, with a global presence in pharmaceutical, food, and nutritional supplements sectors

Pharmaceutical Manufacturing 🇪🇸 Esplugues de Llobregat 765 2003
27
Towa Internationaltowainternational.com

An international pharmaceutical company specializing in researching, developing, manufacturing, and marketing generic and value-added medicines to improve global health

Pharmaceutical Manufacturing 🇪🇸 Barcelona 750 2020
28
IQVIA Spainiqvia.com

Accelerating innovation in healthcare, improving drug development, ensuring product quality and safety, enhancing commercial efficacy, providing proper treatments to patients, and optimizing healthcare delivery

Hospitals and Health Care 🇪🇸 Madrid 726 1960
29
Prim, S.A.prim.es

A Spanish private capital group in the healthcare sector, providing advanced products and solutions to hospitals, clinics, health centers, and individuals

Wellness and Fitness Services 🇪🇸 Móstoles 711 n/a
30
Ercrosercros.es

A diversified industrial group with a century-old tradition, focusing on chlorine derivatives, intermediate chemicals, and pharmaceuticals Committed to safety, health, environment, quality, and transparency

Chemical Manufacturing 🇪🇸 Barcelona 705 1989
31
Promedonpromedon.com

International leader in medical technology research, development, production, and distribution Specializes in Urology, Urogynecology, Sports Medicine, Arthroscopy, and various surgical solutions in multiple countries

Medical Equipment Manufacturing 🇪🇸 Córdoba 685 1985
32
Dentaiddentaid.com

A global leader in oral health research, transforming science into innovative oral healthcare solutions to enhance people's well-being

Wellness and Fitness Services 🇪🇸 Cerdanyola 665 1980
33
Lacerlacer.com

Spanish company specializing in pharmaceutical, healthcare, and personal-care products with leading cardiovascular products in the Spanish market.

Pharmaceutical Manufacturing 🇪🇸 Barcelona 644 n/a
34
BioSystemsbiosystems.global

Global group specializing in In-vitro human and veterinary clinical diagnostics, food & beverage analysis, and bioprocess monitoring, with a focus on user experience and innovation

Biotechnology Research 🇪🇸 Barcelona 643 1981
35
LETI Pharmaleti.com

A family-owned biopharmaceutical company specializing in immunotherapy using allergens for personalized medicine in human and animal health

Pharmaceutical Manufacturing 🇪🇸 Tres Cantos 620 1919
36
Grupo Vall Companysvallcompanys.es

A leading group in the agri-food sector with over 45 companies in Spain and Portugal, specializing in flour, feed, meat production, pharmaceuticals, logistics, and more

Food and Beverage Services 🇪🇸 Lleida 591 1956
37
LABORATORIO ECHEVARNElaboratorioechevarne.com

A part of Grupo Echevarne, this company focuses on providing innovative technology and services in healthcare, veterinary, and industry sectors

Medical and Diagnostic Laboratories 🇪🇸 Barcelona 588 1958
38
Grupo Menarini Españamenarini.es

Grupo Menarini is committed to providing new and improved healthcare products, employing over 16,000 globally with a focus on integrity, ethics, quality, and social responsibility

Pharmaceutical Manufacturing 🇪🇸 Badalona 571 1961
39
Banc de Sang i Teixitsbancsang.net

A public company in Catalonia providing blood, tissues, and breast milk to patients, while also leading in research for therapies

Public Health 🇪🇸 Barcelona 568 n/a
40
Syntegon Telstartelstar.com

A leading engineering company offering integrated solutions for life sciences, high technology industry, and scientific research through equipment, projects, and services

Machinery Manufacturing 🇪🇸 Terrassa 529 1963
41
Hologic (Formerly Gen-Probe)hologic.com

Develops, markets, and services innovative diagnostic imaging systems and surgical products globally, providing greater confidence in diagnoses and enabling healthier lives for people everywhere.

Biotechnology Research 🇪🇸 520 1986
42
PharmaMarpharmamar.com

A Madrid-based biopharmaceutical company specializing in oncology, deriving inspiration from the sea to discover antitumor molecules and provide innovative cancer treatments worldwide

Biotechnology Research 🇪🇸 Colmenar Viejo 508 1986
43
Roche Diagnostics Españaroche.es

A global company pioneering research in diagnostic solutions to advance science, improve lives, and lead personalized medicine with integrated healthcare solutions

Biotechnology Research 🇪🇸 Sant Cugat del Vallès 482 1896
44
Roche Farma Españaroche.es

A leading healthcare company focused on research and development of medications and diagnostic products to advance science and improve people's lives

Pharmaceutical Manufacturing 🇪🇸 Madrid 470 n/a
45
MSD Españamsd.es

A leading global biopharmaceutical company dedicated to developing life-saving medicines and vaccines, focused on research for innovative health solutions

Pharmaceutical Manufacturing 🇪🇸 Madrid 453 1968
46
Farmhispania Groupfarmhispaniagroup.com

A leading pharmaceutical group in Spain specializing in process development with advanced technologies, collaborations with research organizations, and strict adherence to cGMP guidelines

Pharmaceutical Manufacturing 🇪🇸 Barcelona 432 n/a
47
Salvatsvt.com

The company is dedicated to providing safe and effective drugs, focusing on improving the quality of life for patients and society

Pharmaceutical Manufacturing 🇪🇸 Esplugues de Llobregat 426 1955
48
mesoestetic Pharma Groupmesoestetic.es

A leading pharmaceutical laboratory specializing in dermatology and aesthetic medicine, offering innovative solutions for skin treatment, including cosmeceuticals and medical devices

Pharmaceutical Manufacturing 🇪🇸 Viladecans 424 1985
49
Inibsainibsa.com

A Barcelona-based pharmaceutical company with 75 years of experience, specializing in dental products and services sold in over 60 countries

Pharmaceutical Manufacturing 🇪🇸 Lliçà de Vall 411 1948
50
Novartis Españanovartis.com

A global leader in pharmaceuticals, Novartis focuses on innovation and science to develop transformative treatments, reaching over 800 million people worldwide

Pharmaceutical Manufacturing 🇪🇸 Barcelona 396 n/a

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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