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List of companies with in-house R&D in the Czech Republic

Tamtam tracks 99 companies with in-house R&D headquartered in the Czech Republic. This list ranks the 50 largest by number of employees on LinkedIn, led by ExxonMobil, Škoda Auto and Zentiva. Their median headcount is 633. Half of them were founded in 1971 or later. The most common headquarters are Prague (25) and Brno (5).

🇨🇿 Czech Republic50 companiesUpdated Nov 12, 2026

These companies with in-house R&D in the Czech Republic span several key sectors, including manufacturing, IT, and higher education. The list features a mix of very large corporations like ExxonMobil, which conducts pioneering research in energy, and established Czech entities such as Škoda Auto, known for designing and manufacturing vehicles. Other significant players include Zentiva, a pan-European pharmaceutical company, and Unicorn, an IT services provider.

A notable pattern among these organizations is the strong presence of academic institutions. Masarykova univerzita in Brno, along with Charles University and the Czech Technical University in Prague, represent a significant portion of the R&D landscape. Furthermore, many of these entities, such as Škoda Group in Plzeň, have long histories, indicating a tradition of innovation within the country.

#CompanyIndustryHeadquarters EmployeesFounded
1
ExxonMobilcorporate.exxonmobil.com

Scientists and engineers pioneering research, pursuing new technologies to reduce emissions, creating efficient fuels, meeting global energy needs, aiming net-zero emissions by 2050.

Oil and Gas 🇨🇿 73,163 n/a
2
Škoda Autoskoda-career.com

Design and manufacture progressive vehicles including bicycles, motorcycles, and cars, focusing on innovation, technology, and employee development.

Motor Vehicle Manufacturing 🇨🇿 Mladá Boleslav 9,865 n/a
3
Zentivazentiva.com

A Pan-European pharmaceutical company developing, manufacturing, and providing affordable medicines in key therapeutic areas with a focus on growth and supply security

Pharmaceutical Manufacturing 🇨🇿 Prague 3,665 1488
4
Masarykova univerzitamuni.cz

A leading educational and scientific institution in the Czech Republic, known for its democratic traditions and commitment to values like freedom and responsibility

Higher Education 🇨🇿 Brno 2,127 1919
5
Unicornunicorn.com

A European IT company providing high value solutions for various industries, offering internet services for small businesses and promoting online education

IT Services and IT Consulting 🇨🇿 Prague 2,105 1990
6
Škoda Groupskodagroup.com

Designing, producing, and supplying custom transport solutions including trams, locomotives, subway trains, and trolleybuses, along with motors and driving gears.

Railroad Equipment Manufacturing 🇨🇿 Plzeň 2,058 1859
7
Czech Technical University in Praguecvut.cz

Leading Central European technical institution providing engineering, architecture, and business education through eight faculties, specialized research laboratories, and diverse degree programs for students.

Higher Education 🇨🇿 Prague 1,948 1707
8
Seznam.czo-seznam.cz

Leading web portal and search engine in the Czech Republic, founded in 1996 Achieved 3 billion CZK revenue in 2014 and continues to grow

Technology, Information and Internet 🇨🇿 Prague 1,831 1996
9
Charles Universitycuni.cz

A prestigious university in Prague, founded in 1348, offering a wide range of academic programs with a strong focus on Natural Sciences

Higher Education 🇨🇿 Prague 1,798 n/a
10
České dráhy, a.s.ceskedrahy.cz

The largest railway carrier in the Czech Republic, providing passenger and freight services with 21,000 employees and a focus on modernizing the country's railway system

Rail Transportation 🇨🇿 Prague 1,585 n/a
11
FF Groupff-group.ai

An innovative data solution provider specializing in Edge and data solutions for road traffic and parking vendors, offering AI intelligence platform for informed decisions

Software Development 🇨🇿 Prague 1,386 2005
12
Metrostav a.s.metrostav.cz

A leading construction firm in the Czech Republic, part of a group working on projects domestically and internationally, with a strong reputation and significant revenues

Construction 🇨🇿 Prague 1,154 1971
13
Czech University of Life Sciences Pragueczu.cz

A top Prague university with over 21,000 students focusing on economics, management, ecology, technology, agriculture, forestry, and natural sciences

Higher Education 🇨🇿 Prague 1,095 1906
14
Všeobecná fakultní nemocnice v Prazevfn.cz

A leading university hospital in Prague providing a wide range of medical services, innovative treatments, and high-tech medicine at a world-class level

Hospitals and Health Care 🇨🇿 Prague 928 1790
15
University of Chemistry and Technology in Prague (UCT Prague)vscht.cz

Leading educational institution in Central Europe with almost 200 years of tradition, offering advanced technologies, international student exchanges, and prestigious career opportunities

Higher Education 🇨🇿 Prague 924 1952
16
University of Ostravaosu.cz

An institution in Ostrava promoting humanities, medical science, art, and regional development, with a focus on societal issues, international cooperation, and inclusive education

Higher Education 🇨🇿 Ostrava 870 1991
17
Palacký University Olomoucupol.cz

A prestigious university in Olomouc, with a history dating back to 1573, offering education in various fields to over 23,000 students

Higher Education 🇨🇿 Olomouc 839 n/a
18
Technical University of Liberectul.cz

Medium-sized university offering diverse technical, scientific, humanities, and artistic programs with strong research, modern facilities, and international appeal.

Higher Education 🇨🇿 Liberec 1 804 1953
19
Bobcat EMEAbobcat.com

Leading global manufacturer of compact equipment for various industries, with roots in North Dakota since 1947, now with manufacturing facilities in four countries

Machinery Manufacturing 🇨🇿 Dobříš 778 1947
20
St. Anne's University Hospital Brnofnusa-icrc.org

A prestigious hospital with over 220 years of history, offering state-of-the-art medical care, specialized in cardiovascular issues, oncosurgery, neurosciences, and more

Hospitals and Health Care 🇨🇿 Brno 767 1786
21
Makemake.com

It is a leading automation platform that allows users to design and build custom solutions for tasks, workflows, and applications.

Software Development 🇨🇿 Prague 707 n/a
22
AERO Vodochody AEROSPACE a.s.aero.cz

A leading Czech aviation manufacturer specializing in military and civil aircraft design, production, and service support worldwide

Aviation and Aerospace Component Manufacturing 🇨🇿 Odolena Voda 673 1919
23
Fakultní nemocnice Brnofnbrno.cz

The largest healthcare facility in Moravia providing specialized medical care across all fields, equipped with modern technologies, expert teams, and research collaboration with Masaryk University

Hospitals and Health Care 🇨🇿 Brno 651 n/a
24
Fakultní nemocnice Bulovkabulovka.cz

A leading Prague hospital providing specialized medical care, with 25 departments, 7 clinics, 2 institutes, and 12 outpatient clinics Includes extensive services and facilities

Hospitals and Health Care 🇨🇿 Prague 638 1931
25
ComAp Groupcomap-control.com

Provider of smart power control solutions and services for independent and backup power generation markets, with a focus on flexibility, scalability, and sustainability

Appliances, Electrical, and Electronics Manufacturing 🇨🇿 Prague 633 1991

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26
BTL Medical & Healthcare Technologiesbtl-kariera.cz

Company brings disruptive technologies to healthcare, focusing on cardiology, physical therapy, and medical aesthetics. Develops and produces devices from idea to serial production, distributing globally.

Medical Equipment Manufacturing 🇨🇿 Prague 630 1993
27
TATRA TRUCKS a.s.tatra.cz

World-famous producer of heavy-duty vehicles with a rich history, unique chassis concept, modern technology, and involvement in cultural and sporting events

Motor Vehicle Manufacturing 🇨🇿 Kopřivnice 626 1850
28
Digiteq Automotivedigiteqautomotive.com

A leading service provider for automotive electrical and electronic systems, supporting development, testing, integration, and mass deployment for Volkswagen Group projects

Software Development 🇨🇿 Prague 625 2001
29
Institute for Clinical and Experimental Medicine (IKEM)ikem.cz

A leading clinical and research center in Czech Republic specializing in cardiovascular diseases, organ transplantation, diabetology, and metabolic disorders with extensive facilities and staff

Hospitals and Health Care 🇨🇿 Prague 624 1971
30
Tescantescan.com

A multinational company specializing in scanning electron microscopes, focused ion beam workstations, and 4D-STEM technology for various industries worldwide

Nanotechnology Research 🇨🇿 Brno 620 1991
31
CHROPYNSKA Groupchropynska.com

A leading European automation company providing tailored solutions for manufacturing processes in industries such as automotive, aerospace, and agriculture globally

Automation Machinery Manufacturing 🇨🇿 Chropyně 601 1992
32
Bohemia Interactivebohemia.net

This company started with a successful PC game and has since grown to develop major games that encourage exploration, creation, and connection

Computer Games 🇨🇿 Mníšek pod Brdy 576 1999
33
Solitea, a.s.seyfor.com

A leading Czech software company offering accounting systems, online invoicing services, retail software, and IT solutions for businesses of all sizes

IT Services and IT Consulting 🇨🇿 Brno 544 1990
34
AŽDazd.cz

Producer and supplier of signalling, telecommunication, information, and automation technologies for rail and road transport, including research, development, design, production, and maintenance

Railroad Equipment Manufacturing 🇨🇿 Záběhlice 537 1954
35
Fakultní nemocnice Olomoucfnol.cz

A leading medical facility in the Czech Republic providing a wide range of healthcare services, specializing in surgery, intensive care, and research

Hospitals and Health Care 🇨🇿 Olomouc 537 1896
36
AGEL a.s.agel.cz

A leading healthcare provider in central Europe with hospitals, clinics, pharmacies, laboratories, educational institutes, and foundations in Czech Republic and Slovakia

Hospitals and Health Care 🇨🇿 Praha 5 - Košíře 530 1990
37
Doosan Škoda Powerdoosanskodapower.com

Designing and manufacturing efficient and reliable turbo-generator systems for power generation and industrial applications worldwide, with a focus on steam turbine technology

Oil and Gas 🇨🇿 Plzeň 520 1859
38
PRO.MED.CSpromedcs.com

A leading Czech pharmaceutical company specializing in developing and producing tablets, capsules, and drugs for gastrointestinal, cardiovascular, and musculoskeletal areas Exporting to over 30 countries

Pharmaceutical Manufacturing 🇨🇿 Prague 516 1989
39
University of Hradec Královéuhk.cz

The University of Hradec Králové offers high-quality tertiary education in various study fields for almost 9,000 students through diverse programs

Higher Education 🇨🇿 Hradec Králové 512 1959
40
ZF Engineering Plzeň s.r.o.zf.com

Innovative technology enhances vehicle performance, focusing on driving convenience, safety, reliability, and cost-effectiveness for both manufacturers and consumers

Motor Vehicle Manufacturing 🇨🇿 Plzen 497 n/a
41
Czech Academy of Sciencesavcr.cz

A research academy in Czech Republic specializing in natural, technical, social, and humanities sciences, promoting international collaboration and knowledge application in society and industries

Research Services 🇨🇿 Prague 491 1992
42
Prusa Researchprusa3d.com

A leading manufacturer of 3D printers based in Prague, providing innovative solutions for businesses and individuals worldwide with a focus on growth and quality

Mechanical Or Industrial Engineering 🇨🇿 Prague 489 2012
43
Meopta s.r.o.meopta.com

An international company specializing in developing, manufacturing, and assembling high-quality optical products for industrial, military, and consumer markets worldwide

Semiconductor Manufacturing 🇨🇿 Prerov 480 1933
44
ICZ Groupiczgroup.com

We provide integrated software, networking, and security solutions with a wide range of services in system integration, application development, infrastructure, communication, and security

IT Services and IT Consulting 🇨🇿 Prague 477 1997
45
Bosch Česká republikabosch.cz

A global company known for innovative technologies and groundbreaking inventions in automotive, tools, and more, with over 8000 employees in the Czech Republic

Machinery Manufacturing 🇨🇿 Prague 468 n/a
46
ÚJV Řež, a. s. (Nuclear Research Institute Rez plc)ujv.cz

Specializing in safe energy solutions, ÚJV Řež offers technical services, research, and infrastructure for nuclear energy, industry, and medicine through its subsidiaries

Energy Technology 🇨🇿 Husinec-Řež 460 1955
47
Faculty of Electrical Engineering, Czech Technical University in Praguefel.cvut.cz

Leading technical university in the Czech Republic offering education in electrical engineering, telecommunications, automation, informatics, and computer science, with strong research collaborations and industry partnerships

Higher Education 🇨🇿 Prague 445 n/a
48
Fakultní nemocnice Hradec Královéfnhk.cz

A leading healthcare facility in the Czech Republic, offering complex surgical procedures, advanced diagnostic and treatment technologies, and high-quality research and education services

Medical Practices 🇨🇿 Hradec Králové 434 n/a
49
Finshapefinshape.com

Finshape provides a digital banking platform with personalization capabilities to help European and MENA banks succeed in the digital world

Financial Services 🇨🇿 Prague 432 2021
50
Národní památkový ústavnpu.cz

A national institution in charge of the state's cultural heritage preservation, conducting research, providing expert advice, and managing accessible historical landmarks

Government Administration 🇨🇿 Prague 418 n/a

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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