These Manchester-based companies with in-house R&D are primarily established firms in manufacturing, healthcare, and technology. Notable examples include PZ Cussons, a global household brand company, and THG, a vertically integrated group retailing beauty and nutrition brands. The list also features The University of Manchester, a prestigious educational institution, and Manchester University NHS Foundation Trust, a large UK acute Trust.
The data shows a strong presence of healthcare providers, with three NHS Foundation Trusts – Manchester University, The Christie, and Pennine Care – among the largest employers. This indicates a significant concentration of medical research and patient care services within the city's R&D landscape.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
The University of Manchestermanchester.ac.uk
A prestigious university known for teaching excellence, research innovation, and a history of world firsts, with a large global alumni community |
20,294 | |||
| 2 |
Manchester University NHS Foundation Trustmft.nhs.uk
A large UK acute Trust with nine hospitals providing comprehensive general to highly specialized services to 750,000 people in Manchester and Trafford |
7,150 | |||
| 3 |
PZ Cussonspzcussons.com
Global household brand company offering extraordinary products, recognition for talent, and endless opportunities for those with a positive attitude and ambition |
4,797 | |||
| 4 | 2,506 | ||||
| 5 |
The Christie NHS Foundation Trustchristie.nhs.uk
The company is a leading cancer center in Europe, offering a range of treatments, research, and diagnostic services to patients nationwide |
2,078 | |||
| 6 |
Pennine Care NHS Foundation Trustpenninecare.nhs.uk
Provider of mental health, learning disability, and autism services in Greater Manchester and beyond, including Bury, Oldham, Rochdale, Stockport, Tameside, and Glossop |
1,849 | |||
| 7 |
McBridemcbride.co.uk
This company is a top supplier of private label household and professional cleaning products for Europe's largest retailers, promoting teamwork and positive environment |
1,585 | |||
| 8 |
Hilti Great Britainhilti.co.uk
A global construction technology company providing innovative solutions, services, and products to professionals in over 120 countries, with a commitment to sustainability and employee wellbeing |
1,070 | |||
| 9 |
Renold Ltd.renold.com
Manufacturer of industrial chains and power transmission products serving diverse industries worldwide with a focus on quality and innovation. |
559 | |||
| 10 | 540 | ||||
| 11 |
EPI-USE Labsepiuselabs.com
Global software solutions company specializing in maximizing SAP system performance, simplifying data management, and helping clients navigate business challenges successfully |
454 | |||
| 12 |
Ultimate Productsupplc.com
A global company sourcing, developing, and distributing branded household products to major retailers, with a focus on quality and innovation |
323 | |||
| 13 | 304 | ||||
| 14 |
Chiesi UKchiesi.uk.com
Leading UK pharmaceutical company focused on respiratory treatments, neonatology, organ transplantation, and rare diseases Emphasizes ethical conduct, sustainability, and employee well-being |
276 | |||
| 15 |
Kingsland Drinkskingsland-drinks.com
Independent contract packer and supplier specializing in wine and spirits, offering product creation, bottling, distribution, and marketing services for diverse brands. |
232 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
Calromcalrom.com
Innovative travel software company based in Pakistan and the UK, specializing in automated airline booking platforms and group booking management solutions |
225 | |||
| 17 |
Inspired Global Cuisineinspiredgc.co.uk
Manufacturing ready meal products for retail stores, focusing on quality, team development, and operational excellence at a single site. |
161 | |||
| 18 |
Uniboxunibox.co.uk
Innovative company offering custom visual communication and LED lighting solutions with over 30 years of experience in design and manufacturing |
131 | |||
| 19 |
Luxferluxfer.com
Global materials technology company specializing in high-performance materials, components, and gas cylinders for diverse industries with a focus on innovation and collaboration with customers |
130 | |||
| 20 |
Amelia Knight Cosmetics Ltdameliaknight.com
An award-winning beauty solution provider with global manufacturing capabilities, offering turnkey private label cosmetics, skincare, haircare, body care, and fragrance products worldwide |
108 | |||
| 21 |
Bosch Automotive Service Solutions UKboschautomotiveservicesolutions.com
Providing diagnostic equipment, repair tools, spare parts for vehicles, and IoT solutions globally, focused on innovation and improving quality of life |
93 | |||
| 22 | 82 | ||||
| 23 |
Renthalrenthal.com
A global leader in manufacturing motorcycle and cycle handlebars, chainwheels, and accessories for various markets, with a strong focus on quality and performance |
45 | |||
| 24 |
BHID Groupbhid.co.uk
A UK market leader in luxury interiors, offering bespoke furniture, staircase solutions, kitchens, and high-end doors through three specialist brands |
43 | |||
| 25 |
npdnpd.studio
This company uses the power of design to create sustainable products and experiences that benefit people, businesses, communities, and the planet |
42 | |||
| 26 |
James Robinson Speciality Ingredientsjrsi.com
A research-driven company with over 100 years of experience specializing in creating bespoke ingredients for personal care and speciality chemical industries globally |
36 | |||
| 27 |
Scruffspetslovescruffs.com
A global brand specializing in premium pet bedding and accessories, focused on improving the lives of pets and their owners through innovative and fashionable products |
32 | |||
| 28 |
CNPcnpprofessional.co.uk
Premium sports nutrition experts providing high-quality products formulated with premium grade ingredients, trusted by professional athletes and sports teams worldwide |
30 | |||
| 29 |
Club Systemsclubsystems.com
Specializing in IT systems for golf clubs since 1982, providing solutions for administration, membership, reservations, point of sale, and security |
24 | |||
| 30 |
Avectobeyondtrust.com
Leader in Privileged Access Management, offering seamless prevention of data breaches, empowering organizations with platform for privilege security across various environments |
19 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
More company lists in Manchester
- The largest companies in Manchester 893
- Multinational companies in Manchester 163
- Professional services firms in Manchester 86
- Financial Services companies in Manchester 84
- SaaS companies in Manchester 80
- Retail Apparel and Fashion companies in Manchester 70
- Retail chains in Manchester 68
- Software Development companies in Manchester 68
- Financial services firms in Manchester 64
- Retail companies in Manchester 62
- E-commerce companies in Manchester 50
- Companies with a mobile app in Manchester 50
- Online-only businesses in Manchester 45
- IT Services and IT Consulting companies in Manchester 43
- Marketing and communications agencies in Manchester 39
- Consulting firms in Manchester 39
- IT services companies in Manchester 38
- Hotel and hospitality groups in Manchester 35
- Advertising Services companies in Manchester 35
- Manufacturers in Manchester 35
- Subscription businesses in Manchester 35
- DTC brands in Manchester 30
- Wellness and Fitness Services companies in Manchester 30
- Critical infrastructure operators in Manchester 29
The same list elsewhere in United Kingdom
- Companies with in-house R&D in the United Kingdom 1,930
- Companies with in-house R&D in England 1,703
- Companies with in-house R&D in Scotland 94
- Companies with in-house R&D in Wales 38
- Companies with in-house R&D in Northern Ireland 28
- Companies with in-house R&D in London 477
- Companies with in-house R&D in Cambridge 56
- Companies with in-house R&D in Oxford 39
- Companies with in-house R&D in Nottingham 27