These Oxford-based companies with in-house R&D are primarily focused on healthcare, research, and technology sectors, with a mix of large established institutions and younger, specialized firms. Notable entities include Oxford University Hospitals NHS Foundation Trust, a teaching trust; Unipart, a global supply chain partner; Oxford Nanopore Technologies, a biotech company developing DNA sequencing technology; and Lucy Group Ltd, an international group in sustainable infrastructure and smart energy.
The data shows a strong presence of healthcare providers and research organizations, reflecting Oxford's academic strengths. Additionally, there is a cluster of companies founded in the late 20th and early 21st centuries, such as OXB (1995), Rebellion (1992), and Aurora Energy Research (2013), indicating a sustained period of new company formation.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Oxford University Hospitals NHS Foundation Trustouh.nhs.uk
A world-renowned NHS teaching trust with four hospitals in Oxford, providing clinical services, specialist care, medical education, training, and research |
5,379 | |||
| 2 |
Unipartunipart.com
Global supply chain performance partner designing, making and moving components across automotive, rail, healthcare and technology sectors through data-driven logistics and engineering. |
4,853 | |||
| 3 |
Oxford Health NHS Foundation Trustoxfordhealth.nhs.uk
Provider of physical, mental health, and social care across multiple regions, with a focus on community-based services, research, and collaborations with universities |
3,054 | |||
| 4 |
Lucy Group Ltdlucygroup.com
International group providing sustainable infrastructure, smart energy distribution, advanced street lighting controls, and responsible property development for eco-friendly living. |
1,814 | |||
| 5 |
Oxford Nanopore Technologiesnanoporetech.com
Innovative biotech company developing portable DNA and RNA sequencing technology for real-time data delivery and scalable analysis in over 100 countries worldwide |
1,352 | |||
| 6 |
Aurora Energy Researchauroraer.com
Provide power market forecasting, analytics, advisory support, and software solutions to support investment and financing decisions in energy sector. |
1,188 | |||
| 7 | 940 | ||||
| 8 |
System Csystemc.com
A UK based company specializing in providing health and social care sectors with robust IT solutions, implementation expertise, and innovative consultancy services |
752 | |||
| 9 | 
Oxford Radcliffe Hospitals NHS Trustoxfordradcliffe.nhs.uk
A leading NHS teaching trust offering general and specialist clinical services, medical education, training, and research opportunities |
649 | |||
| 10 | 544 | ||||
| 11 |
Ellison Institute of Technology Oxfordeit.org
Cutting-edge research and development facility focusing on solving humanity's challenges through technology in healthcare, agriculture, energy, and policy |
395 | |||
| 12 |
University of Oxford, Department of Physicslinktr.ee
Cutting-edge research and teaching in physics, exploring nature from the smallest to largest scales and contributing to societal challenges Visit website for more |
309 | |||
| 13 |
Oxford Archaeology Limitedoxfordarchaeology.com
A leading UK archaeology and heritage practice with over 420 specialists, promoting social value of heritage and maintaining high archaeological standards |
255 | |||
| 14 | 245 | ||||
| 15 | 201 | ||||
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| 16 |
Genomicsgenomics.com
Uses large-scale genetic information for preventative medicine and improved drug discovery, offering personalised disease risk estimates and new understanding of disease processes. |
190 | |||
| 17 |
Oxford PVoxfordpv.com
A technology leader in perovskite solar cells, dedicated to developing and commercializing advanced solar technology for more affordable clean energy |
106 | |||
| 18 |
PQShieldpqshield.com
Develops quantum-resistant cryptography solutions, empowering organizations and nations against future cyber threats from quantum computers, modernizing vital security systems and global technology supply chains. |
101 | |||
| 19 |
Brainomixbrainomix.com
This company specializes in creating AI-powered imaging biomarkers for precision medicine, providing software solutions to help physicians make better treatment decisions worldwide |
87 | |||
| 20 |
Moa Technologymoa-technology.com
The company is dedicated to helping farmers combat herbicide resistance by developing new weed control strategies and chemistries using innovative technology |
87 | |||
| 21 |
Ultromicsultromics.com
A leader in AI for echocardiography, enabling early detection and risk stratification of heart failure for better outcomes through automated analysis |
85 | |||
| 22 |
Dionach by Nomiosdionach.com
An independent information security consultancy specializing in Penetration Testing, PCI DSS and ISO 27001 Auditing, Incident Response, and Research & Development |
85 | |||
| 23 |
Elysia - Battery Intelligence from Fortescueelysia.co
A world-leading battery intelligence software harnessing battery expertise to provide unprecedented insights and enhancements for electric vehicles and energy storage |
82 | |||
| 24 |
Adaptix Ltdadaptix.com
Transforming planar X-ray imaging with a Flat Panel X-ray Source for portable, low-cost 3D imaging, supported by prestigious organizations |
73 | |||
| 25 |
Oxford BioTherapeuticsoxfordbiotherapeutics.com
Develops first-in-class immuno-oncology and antibody-drug conjugate therapies, with a lead asset in clinical development. Discovers oncology targets using a proprietary proteomic database. |
71 | |||
| 26 |
Enara Bioenarabio.com
Enara Bio develops cancer immunotherapies targeting Dark Antigens for improved treatment outcomes, using the pioneering EDAPT platform to discover novel targets |
68 | |||
| 27 |
CoreFilingcorefiling.com
A global supplier of financial reporting software with expertise in validation technology, serving regulators, filers, and enterprise organizations worldwide |
63 | |||
| 28 |
Mind Foundrymindfoundry.ai
Develop responsible AI solutions using sensor fusion and machine learning to enhance frontline operations and protect critical infrastructure environments. |
58 | |||
| 29 |
Scancellscancell.co.uk
Developing 'off-the-shelf' vaccines and tumour-specific monoclonal antibodies. These advanced therapeutic programs show promising efficacy in trials for metastatic melanoma and solid tumours. |
58 | |||
| 30 |
Ivy Farm Technologiesivy.farm
A company producing guilt-free real meat that is better for the planet, people, and animals, aiming to change the way we feed the world |
54 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
More company lists in Oxford
The same list elsewhere in United Kingdom
- Companies with in-house R&D in the United Kingdom 1,930
- Companies with in-house R&D in England 1,703
- Companies with in-house R&D in Scotland 94
- Companies with in-house R&D in Wales 38
- Companies with in-house R&D in Northern Ireland 28
- Companies with in-house R&D in London 477
- Companies with in-house R&D in Cambridge 56
- Companies with in-house R&D in Manchester 34
- Companies with in-house R&D in Nottingham 27