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Research institutes headquartered in Pennsylvania

Tamtam tracks 37 research institutes headquartered in Pennsylvania. This list ranks all of them by number of employees on LinkedIn, led by Penn State University, University of Pennsylvania and Penn Medicine, University of Pennsylvania Health System. Their median headcount is 758. Half of them were founded in 1893 or later. The most common headquarters are Philadelphia (16), Pittsburgh (12) and Bethlehem (2).

馃嚭馃嚫 Pennsylvania37 companiesUpdated Nov 2, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
Penn State Universitypsu.edu

Providing interdisciplinary education and resources across multiple campuses, fostering student success and positive global community impact through knowledge and experience.

Higher Education 馃嚭馃嚫 University Park 31,986 1855
2
University of Pennsylvaniaupenn.edu

Renowned Ivy League university with 12 schools offering a wide range of programs including arts, sciences, engineering, business, and medicine

Higher Education 馃嚭馃嚫 Philadelphia 22,558 1740
3
Penn Medicine, University of Pennsylvania Health Systempennmedicine.org

Leading academic medical center combining cutting-edge research, comprehensive patient care, and education to improve health and transform lives regionally.

Hospitals and Health Care 馃嚭馃嚫 Philadelphia 21,979 n/a
4
University of Pittsburghpitt.edu

Top-ranked public institution in Pennsylvania, member of leading research universities Known for innovative discoveries and shaping future paths

Higher Education 馃嚭馃嚫 Pittsburgh 19,349 1787
5
Geisingergeisinger.org

Healthcare organization with 13 hospital campuses, research centers, medical college, and health plan serving millions in Pennsylvania Committed to quality healthcare

Hospitals and Health Care 馃嚭馃嚫 Danville 15,962 1915
6
Temple Universitytemple.edu

A top-tier research institution in a vibrant city, offering diverse degree programs to prepare future leaders for impactful careers

Higher Education 馃嚭馃嚫 Philadelphia 13,124 1884
7
Carnegie Mellon Universitycmu.edu

University providing education that develops problem solvers, innovators, and pioneers in technology and the arts, ready for careers.

Higher Education 馃嚭馃嚫 Pittsburgh 11,021 1900
8
Drexel Universitydrexel.edu

Academically comprehensive urban research university with a globally engaged community and a premier cooperative education program nationwide.

Higher Education 馃嚭馃嚫 Philadelphia 7,580 1891
9
Thomas Jefferson Universityjefferson.edu

University focused on innovative health education, interdisciplinary learning, expert faculty collaboration, and redefining possibilities in health, education, and discovery.

Higher Education 馃嚭馃嚫 Philadelphia 5,700 1824
10
Lehigh Universitywww2.lehigh.edu

A premier residential research university offering rigorous academic programs in various fields to undergraduate and graduate students worldwide Located in Pennsylvania

Higher Education 馃嚭馃嚫 Bethlehem 4,473 1865
11
Naval Nuclear Laboratory (FMP)navalnuclearlab.energy.gov

The company operates the Naval Nuclear Laboratory, supporting the US Naval Nuclear Propulsion Program through research, development, training, and technical support

Defense and Space Manufacturing 馃嚭馃嚫 West Mifflin 3,940 1946
12
West Chester University of Pennsylvaniawcupa.edu

A top regional public university offering over 180 undergraduate and graduate programs, focusing on teaching, research, and community service

Higher Education 馃嚭馃嚫 West Chester 3,581 1871
13
University of Pittsburgh School of Medicinemedschool.pitt.edu

Training physician leaders and scientists to improve health, advance research, promote equity, and collaborate internationally in medicine and education.

Higher Education 馃嚭馃嚫 Pittsburgh 2,199 1886
14
Fox Chase Cancer Centerfoxchase.org

Dedicated cancer hospital with expert multidisciplinary teams advancing prevention, diagnosis, treatment, and survivorship through pioneering research and clinical care.

Hospitals and Health Care 馃嚭馃嚫 Philadelphia 2,146 1904
15
Penn State College of Medicinemed.psu.edu

A leading medical institution focused on training healthcare providers and scientists, improving health outcomes, and advancing medical research worldwide

Higher Education 馃嚭馃嚫 Hershey 1,303 1963
16
Software Engineering Institute | Carnegie Mellon Universitysei.cmu.edu

The company conducts research on software engineering, cybersecurity, and AI, creating and testing innovative technologies for government and private industry since 1984

Software Development 馃嚭馃嚫 Pittsburgh 1,061 1984
17
UPMC Hillman Cancer Centerhillmanresearch.upmc.edu

An NCI-designated cancer center affiliated with a university, providing high-level clinical care, research, and education to cancer patients and professionals

Hospitals and Health Care 馃嚭馃嚫 Pittsburgh 1,028 n/a
18
Temple University - Lewis Katz School of Medicinetemple.edu

Leading medical school offering humanistic education, top clinical training, and groundbreaking research, recognized internationally, honored nationally, and essential locally

Higher Education 馃嚭馃嚫 Philadelphia 1,015 n/a
19
Philadelphia Universityjefferson.edu

A professions-focused university resulting from the merger of two renowned institutions in 2017 Offers over 200 academic programs in various fields

Higher Education 馃嚭馃嚫 Philadelphia 758 1824
20
The Applied Research Laboratory at Penn State Universityarl.psu.edu

An integral part of a leading research university, focusing on national security, economic competitiveness, and quality of life through research, development, and technology transition

Defense and Space Manufacturing 馃嚭馃嚫 State College 600 1945
21
Carnegie Mellon University School of Computer Sciencescs.cmu.edu

They provide education and research opportunities in computer science at a renowned institution known for its excellence in the field

Higher Education 馃嚭馃嚫 Pittsburgh 496 1988
22
The Wistar Institutewistar.org

The institute is dedicated to biomedical research, specializing in cancer and immunology, leading to breakthrough discoveries and training future researchers

Research Services 馃嚭馃嚫 Philadelphia 469 1892
23
University of Pennsylvania Graduate School of Educationgse.upenn.edu

A pioneer in education research, innovation, and leadership development, offering top-ranked graduate programs and a diverse, inclusive community of professionals

Higher Education 馃嚭馃嚫 Philadelphia 443 1893
24
Villanova School of Businessvillanova.edu

The company provides top-ranked undergraduate and graduate business education, emphasizing academic rigor, ethics, leadership, and global citizenship through innovative programs and centers

Higher Education 馃嚭馃嚫 Villanova 384 1922
25
Carnegie Mellon University - Tepper School of Businesscmu.edu

A top-ranked business school pioneering management science education, emphasizing interdisciplinary collaboration, and offering undergraduate, graduate, doctoral, and executive education programs

Education Administration Programs 馃嚭馃嚫 Pittsburgh 383 1949
26
University of Pennsylvania School of Veterinary Medicinevet.upenn.edu

Innovative approach to veterinary medicine, providing medical treatments, public health vigilance, and education on animal and human health connections

Higher Education 馃嚭馃嚫 Philadelphia 377 1884
27
University of Pittsburgh School of Health and Rehabilitation Sciencesshrs.pitt.edu

Industry-leading health care education and research institution offering a wide range of programs in the fields of therapy, counseling, nutrition, and rehabilitation

Higher Education 馃嚭馃嚫 Pittsburgh 356 1969
28
University of Pittsburgh Swanson School of Engineeringengineering.pitt.edu

A top-ranked engineering program focusing on research in sustainability, energy systems, bioengineering, computational modeling, and advanced materials and manufacturing

Higher Education 馃嚭馃嚫 Pittsburgh 351 1846
29
Drexel University's Westphal College of Media Arts & Designdrexel.edu

A college specializing in design, media, and arts education, offering a range of undergraduate and graduate majors with top-ranked programs

Higher Education 馃嚭馃嚫 Philadelphia 335 1891
30
University of Pittsburgh School of Public Healthpublichealth.pitt.edu

A leading institution in public health education and research, partnering with stakeholders to address global health challenges through innovative solutions

Higher Education 馃嚭馃嚫 Pittsburgh 312 1948
31
Penn Dental Medicinedental.upenn.edu

Private, Ivy-League institution with a history deeply rooted in forging precedents in dental education, research, and patient care. Dentistry taught as a specialty of medicine.

Higher Education 馃嚭馃嚫 Philadelphia 312 1878
32
Sidney Kimmel Comprehensive Cancer Center at Jeffersonjeffersonhealth.org

A leading cancer center focused on research, patient care, and education in Greater Philadelphia, striving to improve lives through innovation and breakthroughs #CancerCure

Hospitals and Health Care 馃嚭馃嚫 Philadelphia 244 1996
33
University of Pennsylvania School of Dental Medicinedental.upenn.edu

A prestigious institution that provides dental education, conducts research, and offers patient care within a medical and multidisciplinary university setting

Higher Education 馃嚭馃嚫 Philadelphia 240 1878
34
CERT Division at the Software Engineering Institutecert.org

A trusted authority dedicated to improving cybersecurity by anticipating and solving challenges, offering proactive solutions for securing networked systems

Computer and Network Security 馃嚭馃嚫 Pittsburgh 192 1988
35
Human Engineering Research Laboratoriesherl.pitt.edu

The company specializes in improving mobility and function for people with disabilities through advanced engineering, clinical research, and medical rehabilitation

Hospitals and Health Care 馃嚭馃嚫 Pittsburgh 57 1994
36
University of Pennsylvania - Singh Center for Nanotechnologynano.upenn.edu

Cutting-edge nanotechnology research facilities providing state-of-the-art equipment for nanoscale characterization, measurement, and fabrication Home to three major core research facilities

Higher Education 馃嚭馃嚫 Philadelphia 38 2014
37
Lehigh University Materials Science and Engineeringengineering.lehigh.edu

The company specializes in developing innovative materials to address various societal challenges and equips students with skills to innovate in materials science

Higher Education 馃嚭馃嚫 Bethlehem 21 1865

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 2, 2026.

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