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AI companies headquartered in North Carolina

Tamtam tracks 42 AI companies headquartered in North Carolina. This list ranks all of them by number of employees on LinkedIn, led by IQVIA, Lenovo and Red Hat. Their median headcount is 993. Half of them were founded in 2000 or later. The most common headquarters are Raleigh (14), Durham (8) and Morrisville (6).

馃嚭馃嚫 North Carolina42 companiesUpdated Oct 24, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
IQVIAiqvia.com

Provides clinical research, commercial insights, and healthcare intelligence to life sciences and healthcare industries, accelerating medical treatments for better patient outcomes.

Hospitals and Health Care 馃嚭馃嚫 Durham 80,633 1954
2
Lenovolenovo.com

A global technology powerhouse with a focus on delivering smarter technology through innovation, serving millions of customers worldwide in various markets

IT Services and IT Consulting 馃嚭馃嚫 Morrisville 47,094 1984
3
Red Hatredhat.com

A global leader in enterprise open source solutions, delivering high-performing Linux, hybrid cloud, edge, and Kubernetes technologies through community collaboration Join us and make an impact

Software Development 馃嚭馃嚫 Raleigh 21,000 1993
4
SASsas.com

A trusted analytics partner providing fast and productive AI solutions, empowering customers worldwide with the power to generate insights quickly

Software Development 馃嚭馃嚫 Cary 18,697 1976
5
RTI Internationalrti.org

Independent scientific research institute providing technical, social, statistical, and engineering expertise to solve critical global challenges and improve human conditions.

Research Services 馃嚭馃嚫 Research Triangle Park 6,607 1958
6
Avalaraavalara.com

Provides an agentic AI platform for global tax and compliance, automating calculations, return filings, and exemption certificate management for businesses worldwide.

Software Development 馃嚭馃嚫 Durham 5,649 2004
7
Extreme Networksextremenetworks.com

Leader in AI-powered cloud networking, delivering a unified platform simplifying and securing IT operations, connecting devices, applications, and users for thousands of customers.

Software Development 馃嚭馃嚫 Morrisville 4,064 1996
8
Syncfusionsyncfusion.com

It specializes in .NET, web, and mobile components for enterprise software, offering tools for various frameworks like Blazor and Flutter.

Software Development 馃嚭馃嚫 Morrisville 2,636 2001
9
N-ablen-able.com

Protects businesses from cyberthreats with a unified cyber resiliency platform. Manages, secures, and recovers data using AI-powered technology and partner support.

Computer and Network Security 馃嚭馃嚫 Morrisville 2,289 n/a
10
insightsoftwareinsightsoftware.com

Global provider of reporting, analytics, and performance management solutions empowering finance teams with insights to make informed decisions and drive financial intelligence

Software Development 馃嚭馃嚫 Raleigh 2,267 n/a
11
SPECTRAFORCEspectraforce.com

A rapidly growing staffing firm offering AI-powered talent acquisition services across various sectors, celebrating career transformations and recognized for exceptional client service

Staffing and Recruiting 馃嚭馃嚫 Raleigh 1,943 2004
12
AQuity Solutionsikshealth.com

AQuity provides healthcare solutions with virtual scribes, medical transcription specialists, coders, auditors, and interim management professionals, serving top health systems worldwide

Hospitals and Health Care 馃嚭馃嚫 Cary 1,939 n/a
13
Syneos Health Clinical Solutionssyneoshealth.com

A leading biopharmaceutical solutions organization accelerating customer success by translating insights into outcomes and delivering important therapies worldwide

Pharmaceutical Manufacturing 馃嚭馃嚫 Morrisville 1,569 2017
14
JAGGAERjaggaer.com

It provides enterprise procurement and supplier collaboration solutions, enhancing decision-making and automating processes for organizations globally, with proven expertise.

Software Development 馃嚭馃嚫 Durham 1,474 1995
15
Emergysemergys.com

Empowers businesses to align IT strategies with long-term objectives through comprehensive solutions in enterprise, AI, data, and modern applications, driving innovation and growth.

IT Services and IT Consulting 馃嚭馃嚫 Morrisville 1,413 1998
16
National Gypsum Companynationalgypsum.com

Exclusive service provider of high-performance building products including wallboard, finishing compounds, and cement board marketed under Gold Bond, ProForm, and PermaBASE brands.

Wholesale Building Materials 馃嚭馃嚫 Charlotte 1,259 n/a
17
Measurement Incorporatedmeasurementinc.com

A leading provider of customized educational assessment services, offering performance assessment scoring, test development, and school improvement services nationwide

Education Administration Programs 馃嚭馃嚫 Durham 1,193 1980
18
Prometheus Groupprometheusgroup.com

AI-powered enterprise asset management platform providing real-time intelligence, automated workflows, and business analytics to optimize maintenance, planning, scheduling, and overall operational performance.

Software Development 馃嚭馃嚫 Raleigh 1,178 n/a
19
JMPjmp.com

Innovative statistical software empowering scientists and engineers to discover insights in data, fostering a culture of diversity and camaraderie

Software Development 馃嚭馃嚫 Cary 1,043 1989
20
INC Researchsyneoshealth.com

Syneos Health provides integrated solutions for biopharmaceutical companies, offering expertise, data, and insights to accelerate clinical and commercial success

Pharmaceutical Manufacturing 馃嚭馃嚫 Raleigh 994 2017
21
Pendo.iopendo.io

It provides a product experience platform that enhances software usability, helping companies like Verizon and Salesforce improve product intelligence and user experience.

Software Development 馃嚭馃嚫 Raleigh 993 2013
22
Abrigoabrigo.com

Abrigo provides compliance, credit risk, and lending solutions to help community financial institutions succeed in managing risk and driving growth

Financial Services 馃嚭馃嚫 Raleigh 983 2000
23
Digital.aidigital.ai

An industry-leading technology company empowering Global 5000 enterprises with AI-powered DevOps platform for digital transformation and smarter software investments

Software Development 馃嚭馃嚫 Raleigh 943 n/a
24
Paymentuspaymentus.com

A leading provider of cloud-based bill payment technology, offering flexible and secure electronic payment solutions to over 1,900 billers across North America

Financial Services 馃嚭馃嚫 Charlotte 942 2004
25
Beroe Incberoeinc.com

Providing procurement insights and AI-driven data solutions to help organizations make faster, smarter decisions and mitigate supply risks effectively.

Research Services 馃嚭馃嚫 Raleigh 932 2006
26
Meduit | Driving Revenue Cycle Performancemeduitrcm.com

An innovative RCM company collaborates with leading firms to improve revenue cycle management for healthcare organizations, focusing on financial, operational, and clinical performance

Financial Services 馃嚭馃嚫 Charlotte 886 2017
27
Inteleradintelerad.com

Innovative technology for healthcare: scalable medical imaging platform connecting clinicians to fast, smart imaging ecosystem for improved efficiency and population health Visit website

Software Development 馃嚭馃嚫 Raleigh 839 n/a
28
Transportation Insighttransportationinsight.com

provides expert logistics solutions and technology for transportation planning, freight auditing, parcel optimization, and carrier procurement

Truck Transportation 馃嚭馃嚫 Hickory 826 2000
29
Automatic Data Processingadp.com

Global provider of cloud-based HCM solutions including HR, payroll, talent, and benefits administration Specializes in decision support technology customization for companies

Human Resources Services 馃嚭馃嚫 Durham 793 1997
30
Teamworksteamworks.com

Specialized platform for high performance management, recruitment, branding, and community building for sports, military, and public safety organizations worldwide

Software Development 馃嚭馃嚫 Durham 785 2005
31
inVentiv Health Clinicalsyneoshealth.com

Integrated clinical and commercial solutions company dedicated to accelerating biopharmaceutical processes through expertise, data, and insights for global clients

Pharmaceutical Manufacturing 馃嚭馃嚫 Raleigh 757 2017
32
VitalEdge Technologiesvitaledge.com

Global provider of dealer management solutions, offering ERP and software suites for equipment dealers to optimize operations, enhance customer satisfaction, and drive profitability

Software Development 馃嚭馃嚫 Cary 690 2001
33
Prochantprochant.com

A leading reimbursement firm specializing in HME, pharmacy, home health, and hospice, helping providers achieve financial goals with scalable solutions and advanced technology

Hospitals and Health Care 馃嚭馃嚫 Charlotte 681 1999
34
DynPro Inc.dynpro.com

Provides global technology consulting and systems integration, specializing in digital transformation, data modernization, AI, and enterprise platforms for various industries.

IT Services and IT Consulting 馃嚭馃嚫 Raleigh 611 1996
35
PMMCpmmconline.com

PMMC provides revenue cycle management tools to healthcare providers, helping them improve cash flow, efficiency, and competitiveness in today's healthcare environment

Hospitals and Health Care 馃嚭馃嚫 Charlotte 579 1986
36
Relayrelaypro.com

The company provides a communication tool for active workers, integrating PTT functionality with GPS tracking, emergency alerts, and software integrations

Mobile Computing Software Products 馃嚭馃嚫 Raleigh 470 n/a
37
Wellwell.co

Health technology company focused on advancing individualized health through personalized guidance, AI-driven health engine, and cost-saving solutions for employers and individual members

Health and Human Services 馃嚭馃嚫 Chapel Hill 453 2019
38
TeraRecon, Inc.terarecon.com

A global provider of AI-empowered solutions for radiology, oncology, cardiology, neurology, and vascular surgery, improving clinical workflows and delivering actionable insights

Software Development 馃嚭馃嚫 Durham 197 1997
39
JupiterOnejupiterone.com

This company helps organizations secure their attack surface by aggregating and operationalizing asset data, enabling data-driven decisions about risk and security

Software Development 馃嚭馃嚫 Durham 76 n/a
40
BD Parcel Solutionstransportationinsight.com

A global lead logistics provider offering customized supply chain solutions to reduce costs, improve efficiency, and enhance customer satisfaction rates through various services

Transportation, Logistics, Supply Chain and Storage 馃嚭馃嚫 Hickory 66 1998
41
RxDataSciencesyneoshealth.com

Provider of advanced data analytics solutions for biotech, pharmaceutical & healthcare industries using AI & ML technology to enable data-driven decisions and solve business problems

Data Infrastructure and Analytics 馃嚭馃嚫 Morrisville 41 n/a
42
PSPDFKit is now Nutrient SDKnutrient.io

Provides SDKs, cloud document processing, low-code M365 solutions, and workflow automation to modernize and transform document ecosystems globally.

Software Development 馃嚭馃嚫 Raleigh 22 2011

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

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