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49 AI-native companies in Boston

Tamtam tracks 49 AI-native companies headquartered in Boston. This list ranks all of them by number of employees on LinkedIn, led by Motional, DataRobot and Motus. Their median headcount is 149. Half of them were founded in 2017 or later.

馃嚭馃嚫 Boston49 companiesUpdated Oct 8, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
Motionalmotional.com

Innovating driverless technology to create safe, reliable, and accessible vehicles through a joint venture between Aptiv and Hyundai Motor Group

Software Development 馃嚭馃嚫 Boston 970 2020
2
DataRobotdatarobot.com

Value-driven AI company accelerating AI impact with innovative AI lifecycle platform for organizations to build, operate, and govern AI landscapes confidently

Software Development 馃嚭馃嚫 Boston 881 2012
3
Motusmotus.com

Specializes in vehicle reimbursement solutions and driver risk mitigation, leveraging extensive data to reduce corporate risk exposure.

Software Development 馃嚭馃嚫 Boston 840 2004
4
smartShiftsmartshift.com

AI-powered solutions for SAP customers focusing on rapid, secure, and optimized custom code migration and modernization, trusted globally.

Software Development 馃嚭馃嚫 Boston 586 2002
5
Mentor Collectivementorcollective.org

Provider of impact-driven mentoring programs for higher education institutions, with proven results in reducing melt rates and increasing retention Industry-leading and mission-driven Hiring opportunities available

Business Intelligence Platforms 馃嚭馃嚫 Boston 496 2015
6
codemantracodemantra.com

Global leader providing AI-driven Intelligent Document Processing platform for automating digital document accessibility, extraction, classification, and transformation services across various industries

IT Services and IT Consulting 馃嚭馃嚫 Boston 420 2002
7
Lendbuzzlendbuzz.com

An AI auto finance platform using alternative data and machine-learning to provide fair credit access for car purchases to underserved consumers and support dealership growth

Financial Services 馃嚭馃嚫 Boston 389 2015
8
Texttext.com

The company provides tools for better customer service, including live chat, chatbots, helpdesk, knowledge base, and website widgets, enabling automation and scalability

Artificial Intelligence 馃嚭馃嚫 Boston 386 2002
9
Validity Inc.validity.com

It provides solutions for marketing, sales, and customer success teams to effectively target, engage, and retain customers using data.

Software Development 馃嚭馃嚫 Boston 348 2018
10
OVERJEToverjet.com

A dental AI company founded by MIT and Harvard experts, Overjet provides FDA-cleared technology for precise pathology detection and patient education

Software Development 馃嚭馃嚫 Boston 341 2018
11
Cynet Securitycynet.com

All-in-one cybersecurity platform providing unified protection, detection, and expert support tailored for small-to-medium enterprises and MSPs.

Computer and Network Security 馃嚭馃嚫 Boston 334 2014
12
PathAIpathai.com

AI-powered pathology company improving patient outcomes through accurate diagnosis and effective treatment, leveraging machine learning with a diverse and passionate team

Software Development 馃嚭馃嚫 Boston 281 2016
13
Drift, a Salesloft companydrift.com

Inspires businesses engaging customer experiences. Translates conversational data, buyer behavior into deeper relationships, more pipeline and revenue. Human-centric, AI-powered platform delivers personalized experiences.

Software Development 馃嚭馃嚫 Boston 271 2015
14
Mend.iomend.io

A company offering an enterprise suite of application security tools to help build and manage proactive AppSec programs, fostering collaboration between dev and security teams

Software Development 馃嚭馃嚫 Boston 257 2011
15
TetraSciencetetrascience.com

A Scientific Data and AI Cloud platform connecting lab instruments and software to accelerate scientific discovery in the biopharma industry

Software Development 馃嚭馃嚫 Boston 213 2019
16
Lakeside Softwarelakesidesoftware.com

AI-driven platform providing proactive IT management, reducing costs, preventing failures, and enhancing decision-making through comprehensive digital employee experience insights.

Software Development 馃嚭馃嚫 Boston 198 1997
17
Teikametricsteikametrics.com

Teikametrics helps Amazon and Walmartcom sellers grow with AI technology, data analysis, and marketplace expertise Optimizing advertising, inventory, and market intelligence

Technology, Information and Internet 馃嚭馃嚫 Boston 180 2015
18
Videavidea.ai

Transforms dentistry with AI-powered solutions, reducing complexity, elevating care standards, improving productivity, and driving business value across diagnostics, workflows, analytics, and revenue optimization.

Software Development 馃嚭馃嚫 Boston 180 2018
19
Poshposh.ai

Revolutionizing banking with AI technology developed at MIT, Posh automates contact centers and customer interactions for financial institutions Join our innovative team!

Software Development 馃嚭馃嚫 Boston 178 2018
20
Wysawysa.com

An AI-enabled mental wellness platform offering early intervention through AI chatbot, self-help tools, and therapist support, serving millions globally

Mental Health Care 馃嚭馃嚫 Boston 177 2015
21
Originuseorigin.com

Integrated money management platform for modern workforce, offering solutions for compensation, benefits, and personal finances with support from financial professionals

Financial Services 馃嚭馃嚫 Boston 167 2018
22
Beacon Biosignalsbeacon.bio

This company uses an AI platform, FDA-cleared EEG wearables, and machine learning algorithms to develop new treatments for neurological and psychiatric diseases

Software Development 馃嚭馃嚫 Boston 167 2019
23
Minemineos.ai

Leading data privacy platform offering simplified compliance through unique automation and ML-assisted features, making managing data requests, consent, and compliance effortless

Technology, Information and Media 馃嚭馃嚫 Boston 153 2019
24
Findability Sciencesfindability.ai

Findability Sciences specializes in AI solutions for traditional enterprises, offering advanced forecasting and business process co-pilots through their proprietary platform

IT Services and IT Consulting 馃嚭馃嚫 Boston 151 2018
25
Point Wildpointwild.com

Provides AI-driven data breach resilience, response, and remediation for consumer and enterprise endpoints using extensive threat data and network effects.

Data Security Software Products 馃嚭馃嚫 Boston 149 n/a
26
PaxeraHealthpaxerahealth.com

Develops enterprise imaging AI platform and no-code algorithm authoring platform for democratizing AI in medical imaging, improving diagnosis, and reducing physician burnout.

Hospitals and Health Care 馃嚭馃嚫 Boston 149 2009
27
Fairmarkitfairmarkit.com

An autonomous sourcing platform utilizing AI to help organizations source competitively at scale, resulting in significant cost savings for procurement teams

Software Development 馃嚭馃嚫 Boston 146 2017
28
AirWorksairworks.io

Provides software and services for automated field data collection, utilizing AI for infrastructure design and maintenance, offering accurate real-world geospatial insights.

Software Development 馃嚭馃嚫 Boston 140 2017
29
Zoovuzoovu.com

It provides AI-driven product discovery solutions for enterprises, enhancing customer engagement and satisfaction across various channels and product categories.

Technology, Information and Internet 馃嚭馃嚫 Boston 140 2006
30
Gryphon AIgryphon.ai

It offers AI-powered conversation intelligence and compliance solutions, ensuring real-time guidance for sales and customer service teams during calls.

Software Development 馃嚭馃嚫 Boston 134 1999
31
Gradient AIgradientai.com

A leading provider of AI solutions for the insurance industry, improving loss ratios, profitability, and operational efficiencies through predictive analytics and intelligent automation

Software Development 馃嚭馃嚫 Boston 130 2018
32
Mirai RiskTechmirairisktech.com

Global technology leader in Balance Sheet Management, Financial Risks, and Regulation, offering enterprise SaaS solutions and consulting services for banks worldwide

Software Development 馃嚭馃嚫 Boston 120 2013
33
Databoxlinktr.ee

It provides tools for tracking and improving business performance through custom dashboards, reports, and goal-setting, fostering a supportive work environment.

Technology, Information and Internet 馃嚭馃嚫 Boston 116 2012
34
Soniosonio.ai

Innovative women's health practice management software powered by AI for prenatal examinations, ultrasound readings, and clinical excellence throughout pregnancy

Software Development 馃嚭馃嚫 Boston 111 2020
35
Mainstaymainstay.com

The company specializes in an Engagement Platform that facilitates conversations, drives action at scale, and helps individuals progress towards their goals

Higher Education 馃嚭馃嚫 Boston 90 2014
36
Sereactsereact.ai

A company specializing in AI software for autonomous robotics to automate pick-and-place processes and optimize supply chains for increased productivity and cost reduction

Software Development 馃嚭馃嚫 Boston 88 n/a
37
hOS Inchosinc.co

An early-stage AI technology company founded by DataRobot alumni, operating in stealth-mode to develop scalable technologies for positive change

IT Services and IT Consulting 馃嚭馃嚫 Boston 79 n/a
38
United Imaging Intelligenceuii-ai.com

A leading international medical AI company founded in 2017, providing innovative solutions for healthcare through AI technology in various medical fields

Research Services 馃嚭馃嚫 Boston 70 2017
39
lowtouch.ailowtouch.ai

Cloud Control Solutions specializes in Cloud Migration, Modernization, and Management with a Kubernetes-first approach to deliver reliable, cost-optimized solutions

Technology, Information and Internet 馃嚭馃嚫 Boston 65 2018
40
Bluesensesmartbeauty.bluesense.ai

A leading AI company specializing in computer vision, machine learning, and AI technology to create innovative solutions and offer top-notch consultancy services

IT Services and IT Consulting 馃嚭馃嚫 Boston 62 2023
41
Reprisereprise.com

It provides a comprehensive platform for creating customized sales demos, interactive leave-behinds, and product tours for enterprise teams.

Software Development 馃嚭馃嚫 Boston 54 2020
42
EAIGLEeaigle.com

An AI platform for supply chain and retail industries, offering solutions for automated vehicle access control, yard monitoring, and warehouse pallet tracking

Software Development 馃嚭馃嚫 Boston 42 2018
43
Tessianproofpoint.com

A leading cloud email security platform using machine learning to protect organizations against advanced threats and data loss, while coaching on security awareness

Computer and Network Security 馃嚭馃嚫 Boston 41 2013
44
Outcomes4Meoutcomes4me.com

AI-driven platform empowering cancer patients with personalized treatment options, real-time clinical information, and promoting health equity and innovation in healthcare

Wellness and Fitness Services 馃嚭馃嚫 Boston 32 2017
45
APERIOaperio.ai

This company specializes in industrial data quality solutions, utilizing AI machine learning to validate operational data for improved accuracy and decision-making

Software Development 馃嚭馃嚫 Boston 30 2017
46
Yobe Inc.yobeinc.com

Yobe specializes in intelligent voice control software for brands, enabling accurate voice interactions in noisy environments and offering expertise in voice data analysis

Software Development 馃嚭馃嚫 Boston 25 2016
47
Provarityprovarity.ai

It provides an AI-powered platform for sales engineers to enhance efficiency, shorten sales cycles, and improve overall sales performance.

Software Development 馃嚭馃嚫 Boston 23 2018
48
Spiro.AIspiro.ai

It provides AI-driven CRM solutions for manufacturers and distributors, enhancing customer engagement and driving significant business growth through automation.

Software Development 馃嚭馃嚫 Boston 20 2014
49
Waffle Labswaffle-labs.com

An insurtech startup disrupting traditional insurance by providing personalized, transparent, and affordable insurance solutions such as renters, pet, cyber, and term life insurance

Technology, Information and Internet 馃嚭馃嚫 Boston 13 2018

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 8, 2026.

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