Tamtam Start free

The 100 largest AI-native companies in San Francisco

Tamtam tracks 264 AI-native companies headquartered in San Francisco. This list ranks the 100 largest by number of employees on LinkedIn, led by OpenAI, Mercor and Scale AI. Their median headcount is 448. Half of them were founded in 2017 or later.

馃嚭馃嚫 San Francisco100 companiesUpdated Oct 9, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
OpenAIopenai.com

An AI research and deployment company focused on creating safe and beneficial general-purpose artificial intelligence for the benefit of humanity

Research Services 馃嚭馃嚫 San Francisco 9,268 2015
2
Mercormercor.com

Utilizing AI technology, Mercor streamlines the hiring process by sourcing, assessing, and hiring talent seamlessly for businesses

Software Development 馃嚭馃嚫 San Francisco 8,180 2023
3
Scale AIscale.com

Accelerating AI application development by leveraging enterprise data to customize powerful generative models and provide tools for data collection, curation, and optimization

Software Development 馃嚭馃嚫 San Francisco 6,784 2016
4
Cruise - Universitygm.com

Designs, manufactures, and markets self-driving electric vehicles, focusing on advancing autonomous technology for future transportation solutions.

Motor Vehicle Manufacturing 馃嚭馃嚫 San Francisco 3,800 2013
5
Gongvercel.app

Revenue intelligence platform centralizing customer data and automated workflows to provide business insights, helping professional sales teams optimize performance and increase wins.

Software Development 馃嚭馃嚫 San Francisco 2,592 2015
6
Anythingcreate.xyz

AI tool enables non-developers on a team to quickly create components, sites, apps, and internal tools using text and images

Software Development 馃嚭馃嚫 San Francisco 2,478 n/a
7
Crescendocrescendo.ai

Innovative company combining AI technology and human agents for seamless customer service, eliminating traditional industry models Pay for positive outcomes

Technology, Information and Internet 馃嚭馃嚫 San Francisco 2,314 2024
8
Quincequince.com

Direct manufacturer-to-consumer technology platform utilizing demand forecasting and production planning to provide premium quality products without traditional retail markups or inventory inefficiencies.

Retail 馃嚭馃嚫 San Francisco 2,006 2018
9
Innovaccerinnovaccer.com

A leading data platform for value-based care, unifying patient data to improve clinical, financial, and operational outcomes for healthcare organizations

Hospitals and Health Care 馃嚭馃嚫 San Francisco 1,731 2014
10
6sense6sense.com

Predicts potential buyers through AI, recommends engagement actions for anonymous buying teams, and provides tools to create, manage, and convert high-quality pipeline.

Software Development 馃嚭馃嚫 San Francisco 1,603 2013
11
Harveyharvey.ai

Provides AI-driven tools for legal and professional services, enhancing contract analysis, due diligence, compliance, and litigation processes globally.

Software Development 馃嚭馃嚫 San Francisco 1,441 2022
12
Perplexityperplexity.ai

Cutting-edge answer engine providing accurate and updated information to satisfy curiosity and ignite knowledge exploration

Software Development 馃嚭馃嚫 San Francisco 1,413 2022
13
Zipziphq.com

Zip offers a unified platform for streamlined procurement processes, allowing businesses to gain visibility and improve employee experience through automated request routing and workflows

Software Development 馃嚭馃嚫 San Francisco 1,313 2020
14
Factoryfactory.ai

Research lab developing AI-powered Droids to automate and bring autonomy to software engineering processes efficiently and innovatively.

Software Development 馃嚭馃嚫 San Francisco 1,294 2023
15
XtendOpsxtendops.com

XtendOps enhances customer experiences by blending AI technology with a people-first approach, creating more human connections and empowered, loyal agents

Outsourcing and Offshoring Consulting 馃嚭馃嚫 San Francisco 1,261 2019
16
Sierrasierra.ai

Provides conversational AI platform for businesses, helping companies elevate their customer experience using artificial intelligence. Focused on customer interaction.

Software Development 馃嚭馃嚫 San Francisco 1,120 2023
17
Jasperjasper.ai

It offers a generative AI platform tailored for marketing, providing tools for brand control and workflow acceleration for marketers.

Software Development 馃嚭馃嚫 San Francisco 1,035 2020
18
Gupshupgupshup.ai

Leading platform enabling businesses to engage consumers through conversational messaging Supports over 30 channels, 6 billion messages monthly, and global partnerships

IT Services and IT Consulting 馃嚭馃嚫 San Francisco 963 2004
19
Grammarlygrammarly.com

Leading AI writing assistance company. Helps people and organizations with drafting and perfecting messages across 500,000+ apps and websites, ensuring security and privacy.

Software Development 馃嚭馃嚫 San Francisco 962 2009
20
Doximitydoximity.com

A digital platform connecting over 80% of US physicians, providing tools for collaboration, staying updated, managing careers, and conducting virtual patient visits

Software Development 馃嚭馃嚫 San Francisco 914 2010
21
Trusted Healthtrustedhealth.com

A leading labor marketplace and workforce management platform for healthcare, connecting nurses to job opportunities and offering full employer-of-record services

Software Development 馃嚭馃嚫 San Francisco 893 2017
22
Pepperpepper.inc

AI-powered content marketing platform with expert talent marketplace for ideation, creation, management, distribution, and measurement of content marketing

Software Development 馃嚭馃嚫 San Francisco 891 2017
23
Iterableiterable.com

Provides an AI platform for customer engagement, transforming data into personalized experiences across channels to drive measurable growth for enterprises.

Software Development 馃嚭馃嚫 San Francisco 871 2013
24
Ironcladironcladapp.com

AI-powered platform streamlines contract creation, management, and analysis, providing visibility and control for buying and selling processes.

Technology, Information and Internet 馃嚭馃嚫 San Francisco 867 2014
25
Unbabelunbabel.com

Platform combining AI and human editors to provide fast, high-quality translations enabling businesses to offer consistent multilingual customer support globally.

IT Services and IT Consulting 馃嚭馃嚫 San Francisco 850 2013
26
EvenUpevenuplaw.com

Aiming to provide justice for injury victims regardless of income, demographics, or legal representation, prioritizing fairness and equality

Technology, Information and Internet 馃嚭馃嚫 San Francisco 846 2019
27
Heartflowheartflow.com

Advanced AI technology creating personalized 3D heart models from CT scans to improve diagnosis and treatment of coronary artery disease.

Medical Equipment Manufacturing 馃嚭馃嚫 San Francisco 841 2010
28
LILT AIlilt.com

This company offers AI translation solutions for enterprises, combining human expertise with technology to improve global customer experiences and business outcomes

Software Development 馃嚭馃嚫 San Francisco 773 2015
29
Incodeincode.com

Provides an AI-driven platform for accurate identity verification, automating security, maximizing conversions, and preventing fraud for enterprises across various industries.

Software Development 馃嚭馃嚫 San Francisco 665 2015
30
Abridgeabridge.com

An AI-powered platform that transforms medical conversations into structured clinical notes in real-time, enhancing documentation efficiency and enabling clinicians to focus on patient care

Artificial Intelligence 馃嚭馃嚫 San Francisco 637 2018
31
Ontraontra.ai

AI-powered solutions transforming private market workflows by automating negotiation, compliance, and governance using data and legal expertise.

Software Development 馃嚭馃嚫 San Francisco 607 2014
32
Hightouchhightouch.com

It is a Composable Customer Data Platform that enables companies to utilize their data warehouse for personalized marketing and operations.

Software Development 馃嚭馃嚫 San Francisco 590 n/a
33
Woflowwoflow.com

Woflow automates merchant data onboarding for platforms and marketplaces using ML-powered technology, trusted by top investors and companies globally

Software Development 馃嚭馃嚫 San Francisco 586 2017
34
WRITERwriter.com

Generative AI platform for enterprises enabling creativity and productivity, securely integrating with business data sources to deliver tailored content Compliant with major regulations

Software Development 馃嚭馃嚫 San Francisco 578 2020
35
Medallionmedallion.co

AI-powered platform automates credentialing, payer enrollment, monitoring, and licensing to streamline healthcare provider operations and ensure compliance.

Hospitals and Health Care 馃嚭馃嚫 San Francisco 574 2020
36
FLYRflyr.com

A travel technology company leveraging deep learning AI to help airlines and hospitality businesses improve revenue performance and modernize e-commerce

Software Development 馃嚭馃嚫 San Francisco 560 n/a
37
Monte Carlomontecarlo.ai

The company specializes in reducing downtime through data analysis and optimization

Software Development 馃嚭馃嚫 San Francisco 549 2019
38
Starship Technologiesstarship.xyz

Self-driving delivery robots company revolutionizing last mile logistics, with over 5 million autonomous deliveries completed worldwide Offices in San Francisco, Estonia, and UK

Consumer Services 馃嚭馃嚫 San Francisco 546 2014
39
Latticelattice.com

AI-powered platform transforming managers into leaders, enhancing employee performance, and helping companies create exceptional workplaces with integrated HR tools.

Software Development 馃嚭馃嚫 San Francisco 527 2015
40
Quantcastquantcast.com

An AI-powered ad platform for performance marketers, simplifying open internet advertising with audience intelligence, workflow simplicity, and cookieless reach for measurable growth.

Technology, Information and Internet 馃嚭馃嚫 San Francisco 524 2006
41
Agencyagen.cy

This company creates virtual employees through stafai and agentopsai to assist in various tasks while ensuring job security

Software Development 馃嚭馃嚫 San Francisco 516 2023
42
Gemgem.com

AI-powered recruiting platform integrating ATS, CRM, sourcing, scheduling, and analytics with extensive profiles to boost recruiter productivity and reduce costs.

Software Development 馃嚭馃嚫 San Francisco 515 2017
43
Hivethehive.ai

Provider of cloud-based AI solutions for content understanding, search, and generation Offers pre-trained models, turnkey software, and deep learning applications for businesses

Software Development 馃嚭馃嚫 San Francisco 514 2013
44
Nooksnooks.ai

It provides an AI Sales Assistant Platform that automates repetitive tasks, allowing sales representatives to concentrate on building relationships and increasing sales.

Software Development 馃嚭馃嚫 San Francisco 488 n/a
45
Sensesensehq.com

AI-powered Talent Engagement Platform revolutionizing recruitment with personalized candidate experiences, recruiter efficiency tools, and cutting-edge technology for every step of talent acquisition journey

Software Development 馃嚭馃嚫 San Francisco 485 2016
46
Labelboxlabelbox.com

A data-centric AI platform enabling organizations to launch initiatives efficiently with LLMS, generative AI, and more for building AI and automating tasks

Software Development 馃嚭馃嚫 San Francisco 478 2018
47
Kommokommo.com

It provides an automated sales process for small teams, offering easy setup, support, and a recurring sales pipeline for SaaS.

Software Development 馃嚭馃嚫 San Francisco 475 2009
48
Dashversedashtoon.com

Revolutionary platform utilizing Generative AI for storytellers to easily create illustrated content with unprecedented speed and ease

Technology, Information and Internet 馃嚭馃嚫 San Francisco 463 2022
49
Haushaus.io

Platform measuring incremental ROI of online and offline ad spend, enabling brands to optimize budget allocation and maximize growth.

Software Development 馃嚭馃嚫 San Francisco 450 2021
50
Decagondecagon.ai

Conversational AI platform delivering intelligent, human-like responses across chat, email, and voice to enhance customer experience globally.

Software Development 馃嚭馃嚫 San Francisco 448 2023
51
Cantina Labscantina.com

Developing an innovative social AI platform to revolutionize the way people interact and engage online

Software Development 馃嚭馃嚫 San Francisco 442 2023
52
Algonomyalgonomy.com

Automating decisioning across retail functions: eCommerce, marketing, merchandising, supply chain. Using AI, real-time customer data, personalization, and product recommendations.

Software Development 馃嚭馃嚫 San Francisco 440 2004
53
data.ai (by Sensor Tower)data.ai

Provides unified digital data standards and mobile app performance measurement using applied artificial intelligence to help enterprise brands optimize their digital experiences.

Software Development 馃嚭馃嚫 San Francisco 432 2010
54
Sprintosprinto.com

Autonomous Trust Platform detecting risks and acting across compliance, vendor risk, and AI governance, ensuring organizational trustworthiness without operational chaos for 3,000+ companies globally.

Software Development 馃嚭馃嚫 San Francisco 429 2020
55
Augmedixaugmedix.com

Uses ambient AI and data to transform patient conversations into medical notes and structured data, improving clinician efficiency and decision support.

Hospitals and Health Care 馃嚭馃嚫 San Francisco 424 2012
56
Fountainfountain.com

An all-in-one high volume hiring platform that enables enterprises to streamline recruiting, automate processes, and make data-driven decisions for smarter hiring

Software Development 馃嚭馃嚫 San Francisco 422 2014
57
Simetriksimetrik.com

SaaS and no code solution for financial and operational reconciliation automation, providing a detailed single source of truth for reporting and accounting

Software Development 馃嚭馃嚫 San Francisco 401 2017
58
Vyrovyro.ai

Content creation tools powered by AI & ML empowering users to express creativity Offers 20 apps with 5M active users/month Seeking passionate team members

Software Development 馃嚭馃嚫 San Francisco 387 2018
59
Ousterouster.com

A global provider of lidar sensors and software solutions for automotive, industrial, robotics, and smart infrastructure industries, focused on automation and autonomy

Automation Machinery Manufacturing 馃嚭馃嚫 San Francisco 386 2015
60
Together AItogether.ai

AI native cloud purpose-built for engineers and researchers, offering tooling across inference, model shaping, and pre-training, enabling reliable scaling of AI-native applications.

Software Development 馃嚭馃嚫 San Francisco 385 2022
61
Owner.comowner.com

Software platform enabling local restaurants to compete with national brands by providing a proven system for online growth and success.

Software Development 馃嚭馃嚫 San Francisco 383 2020
62
Directlydirectly.com

A pioneer in customer service solutions for leading brands, offering AI-driven support to boost CSAT, reduce contact center volume, and save millions annually

Technology, Information and Internet 馃嚭馃嚫 San Francisco 383 2011
63
Braintrustusebraintrust.com

End-to-end AI recruiting platform using proprietary data to screen, match, and hire pre-vetted candidates for enterprises, reducing costs and recruitment time.

Technology, Information and Internet 馃嚭馃嚫 San Francisco 373 2018
64
Higgsfield AIhiggsfield.ai

A video AI company focused on making social media content creation accessible to all

Technology, Information and Internet 馃嚭馃嚫 San Francisco 372 2023
65
PolyAIpoly.ai

The company develops advanced conversational AI assistants that provide natural and effective customer service by understanding diverse language expressions

Software Development 馃嚭馃嚫 San Francisco 371 2017
66
Canary Technologiescanarytechnologies.com

Hospitality software solutions provider trusted by thousands of hotels worldwide, offering secure guest data management and enhancing guest experience through innovative solutions

Hospitality 馃嚭馃嚫 San Francisco 371 n/a
67
SuperAnnotatesuperannotate.com

A platform specializing in AI model training data management, annotation tools, automation features, and expert annotation workforce for successful ML pipelines

Software Development 馃嚭馃嚫 San Francisco 368 2018
68
NeuRetailneuretail.ai

A team of engineers and tech enthusiasts created a platform where products can communicate directly with people - neuretailai

Software Development 馃嚭馃嚫 San Francisco 363 2022
69
Arinearine.io

This company optimizes medication therapy and treatment plans, utilizing predictive analytics, AI, and machine learning to improve patient care outcomes and reduce healthcare costs

Hospitals and Health Care 馃嚭馃嚫 San Francisco 361 n/a
70
Gammagamma.app

AI-powered platform enabling fast creation of presentations, websites, social media content, and other design projects with ease.

Software Development 馃嚭馃嚫 San Francisco 360 2020
71
LangChainlangchain.com

The company enables developers to easily build LLM apps quickly, supporting over 50k companies with LangChain and LangSmith for AI engineering

Technology, Information and Internet 馃嚭馃嚫 San Francisco 357 n/a
72
Poolsidepoolside.ai

Developing advanced AI technology for software development to empower developers and maximize their potential

Software Development 馃嚭馃嚫 San Francisco 346 2023
73
You.comyou.com

Productivity engine with AI Assistants helping users with research, analysis, problem-solving, and personalized content creation, trusted by businesses for employee and product potential.

Software Development 馃嚭馃嚫 San Francisco 342 2020
74
ujet.cxujet.cx

Leader in AI-powered contact center innovation, providing a future-proof cloud platform with cutting-edge AI for enhanced customer experiences and operational efficiency

Software Development 馃嚭馃嚫 San Francisco 337 2015
75
Abby Careabbycare.org

Training and employing family caregivers to get paid for home care, improving health outcomes through a tech-driven platform.

Technology, Information and Internet 馃嚭馃嚫 San Francisco 335 n/a
76
Yaloyalo.ai

Yalo helps enterprises drive revenue through Conversational Commerce by using a Commerce Engine to grow presence on messaging apps for customer conversations

Software Development 馃嚭馃嚫 San Francisco 334 2015
77
Sardinesardine.ai

A leading company in financial crime prevention, using advanced technology to detect and prevent fraud, money laundering, and other illicit activities for over 250 clients

Financial Services 馃嚭馃嚫 San Francisco 334 2020
78
testRigortestrigor.com

Empowers manual testers to build test automation via executable specifications in plain English, 15 times faster, with 200 times less maintenance.

Software Development 馃嚭馃嚫 San Francisco 331 2015
79
Nimblenimble.ai

Development of autonomous warehouse robots performing storage, retrieval, picking, packing, and sorting to simplify and reduce logistics costs.

Robotics Engineering 馃嚭馃嚫 San Francisco 329 2019
80
Viz.aiviz.ai

Pioneering AI technology speeds up diagnosis and care, impacting millions of lives in hospitals in the US and Europe

Hospitals and Health Care 馃嚭馃嚫 San Francisco 328 2016
81
Deepgramdeepgram.com

Foundational AI company providing advanced speech transcription and understanding through API Offers fast, accurate transcription, live-streaming capabilities, multiple languages, and custom model training

Software Development 馃嚭馃嚫 San Francisco 326 2015
82
Bright Moneybit.ly

Bright offers AI-powered tools and tailored credit products to help consumers eliminate various types of debt and achieve financial freedom

Financial Services 馃嚭馃嚫 San Francisco 325 2019
83
HoneyBookhoneybook.com

Provides an AI-powered business management platform for small business owners for lead capture, client communication, contracts, payments, and growth automation.

Software Development 馃嚭馃嚫 San Francisco 320 2013
84
Inkittinkitt.com

Inkitt is a data-driven publishing company that discovers and develops talented authors globally, changing the traditional publishing model with innovative algorithms

Entertainment Providers 馃嚭馃嚫 San Francisco 319 2014
85
Helpshifthelpshift.com

A digital support platform using AI and automation to resolve consumer issues efficiently across various channels in 150+ languages

Software Development 馃嚭馃嚫 San Francisco 318 n/a
86
Nanonetsnanonets.com

Nanonets offers AI-driven document automation solutions, utilizing OCR and deep learning to streamline data extraction and processing for businesses.

Software Development 馃嚭馃嚫 San Francisco 317 2017
87
Flamflamapp.ai

The company specializes in reimagining digital experiences through AI technology for creating immersive 3D XR content at scale

Technology, Information and Internet 馃嚭馃嚫 San Francisco 315 2021
88
ChangeEnginechangeengine.com

Elevating people leaders by streamlining and sustaining best-in-class employee experience programs through innovative technology solutions

Software Development 馃嚭馃嚫 San Francisco 314 2021
89
Pantherpanther.com

Provides an AI SOC Platform that scales security expertise by embedding AI agents across security operations with native access to data.

Computer and Network Security 馃嚭馃嚫 San Francisco 312 2018
90
Rizzlerizzle.com

This company utilizes AI to quickly create teasers and highlights from podcasts and videos, working with top partners for high-quality content

Technology, Information and Internet 馃嚭馃嚫 San Francisco 305 2019
91
Weights & Biaseswandb.ai

Developer-focused MLOps platform helping teams track, optimize, visualize, and collaborate on machine learning models and data pipelines for reproducibility and productivity

Software Development 馃嚭馃嚫 San Francisco 305 2017
92
Sanitysanity.io

Fully customizable backend platform enabling AI, automations, and applications to author, render, and manage all content operations centrally.

Software Development 馃嚭馃嚫 San Francisco 303 2018
93
Pavepave.com

A suite of real-time compensation tools for companies to benchmark, plan, and communicate compensation effectively

Software Development 馃嚭馃嚫 San Francisco 286 2019
94
GoodData.AIgooddata.ai

Cloud-based platform leveraging AI for data analytics, enabling real-time, self-service insights for businesses globally to drive meaningful change and achieve more through data

Software Development 馃嚭馃嚫 San Francisco 282 2007
95
Plaudplaud.ai

A profitable AI hardware startup connecting AI with real-life data through innovative AI voice recorder technology and transcription services

Software Development 馃嚭馃嚫 San Francisco 274 2021
96
Personal AIpersonal.ai

A personalized AI platform that creates a digital encyclopedia of users based on their data, ensuring ownership and individuality Available on various devices

Software Development 馃嚭馃嚫 San Francisco 270 2020
97
Figure Eightfigure-eight.com

This company provides high-quality annotated training data for machine learning and business solutions across various industries using human and machine intelligence

IT Services and IT Consulting 馃嚭馃嚫 San Francisco 269 2008
98
Abacus.AIabacus.ai

Creates, deploys, monitors AI agents. Automates workflows and complex decisions. Builds entire software systems, including SaaS apps, from agentic templates.

Software Development 馃嚭馃嚫 San Francisco 268 2019
99
Sprigsprig.com

A user insights platform empowering product teams to improve product experience with tools like Surveys, Replays, and AI Analysis

Software Development 馃嚭馃嚫 San Francisco 266 2019
100
Siftsift.com

Leading fraud prevention platform, delivering digital trust to global brands, stopping fraud, enabling customer experience excellence, converting risk to revenue.

Computer and Network Security 馃嚭馃嚫 San Francisco 263 2011

Turn this list into pipeline

Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.

Build your own list, free

How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 9, 2026.

More company lists in San Francisco

The same list elsewhere in United States