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27 leading e-commerce companies in San Diego

Tamtam tracks 27 e-commerce companies headquartered in San Diego. This list ranks all of them by number of employees on LinkedIn, led by Petco, Pens.com and 100%. Their median headcount is 318. Half of them were founded in 2004 or later.

馃嚭馃嚫 San Diego27 companiesUpdated Nov 2, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
Petcopetco.com

Providing pet products, services, and support to help pets live healthy, happy lives for over 60 years.

Retail 馃嚭馃嚫 San Diego 19,892 1965
2
Pens.compens.com

A global provider of affordable custom promotional products, offering savings, flexibility, and perfect print promise to small businesses worldwide

Advertising Services 馃嚭馃嚫 San Diego 1,537 1966
3
100%100percent.com

A San Diego-based brand producing premium goggles, eyewear, helmets, gloves, and sportswear for motocross, downhill slopes, and BMX racing to inspire a new generation of racers

Retail 馃嚭馃嚫 San Diego 1,318 2012
4
Road Runner Sportsroadrunnersports.com

Provides running shoes, apparel, and accessories, offering a personalized fitting experience to help customers find their ideal gear for an active lifestyle.

Sporting Goods Manufacturing 馃嚭馃嚫 San Diego 779 1983
5
LifeWave Corporatelifewave.com

An innovative health technology company utilizing wearable wellness patches and products to reverse aging, maximize human potential, and promote wellness

Wellness and Fitness Services 馃嚭馃嚫 San Diego 680 2004
6
Pura Vidapuravidabracelets.com

A global brand empowering artisans with sustainable jobs, raising charity awareness through products that give back Founded in Costa Rica

Retail Apparel and Fashion 馃嚭馃嚫 San Diego 674 2010
7
BioLegendbiolegend.com

Developing cutting-edge antibodies, proteins, and bioassays for biomedical research, offering superior products, customer service, and support Revolutionizing healthcare solutions and technologies globally

Biotechnology Research 馃嚭馃嚫 San Diego 660 n/a
8
WAXIE Sanitary Supply, Proudly Part of BradyPLUSwaxie.com

Distributes sanitary products, janitor supplies, and equipment from inventory centers, offering consulting, training, and inventory management for maintenance and janitorial requirements.

Wholesale 馃嚭馃嚫 San Diego 645 n/a
9
Better Buzz Coffeebetterbuzzcoffee.com

A San Diego-based coffee company offering fresh roasted beans, unique blends, and exceptional guest service for a superior coffee experience

Food and Beverage Services 馃嚭馃嚫 San Diego 487 2002
10
Tony Robbinstonyrobbins.com

A leading entrepreneur, bestselling author, and strategist empowering millions worldwide through books, seminars, and personal development events, with a focus on financial freedom and precision medicine

Professional Training and Coaching 馃嚭馃嚫 San Diego 388 n/a
11
ecoATM Gazelleecoatm.com

A San Diego-based company pioneering device re-Commerce through eco-friendly kiosks, providing instant payment and responsible recycling for electronic devices

Retail Recyclable Materials & Used Merchandise 馃嚭馃嚫 San Diego 380 2008
12
San Diego FCsandiegofc.com

A new MLS club in San Diego (2025) affiliated with the Right to Dream community Creating a soccer legacy in California

Spectator Sports 馃嚭馃嚫 San Diego 376 2023
13
Goldstarsimplygoldstar.com

Award-winning manufacturer and supplier of personalized writing instruments, stationery, and drinkware, offering full-color decoration and all-inclusive pricing to promotional product distributors worldwide

Advertising Services 馃嚭馃嚫 San Diego 325 1970
14
Goodwill Industries of San Diego Countysdgoodwill.org

The company provides employment and training opportunities to individuals with disabilities and other barriers to employment

Civic and Social Organizations 馃嚭馃嚫 San Diego 318 1930
15
Damascusdamascusapparel.com

A clothing brand founded to support and empower creators who strive to shape a more beautiful and meaningful world together

Retail Apparel and Fashion 馃嚭馃嚫 San Diego 306 2009
16
LBF Travel, Inc.lbftravel.com

Global travel agency with over 500 professionals, operating online brands and catering to leisure and business travelers worldwide, focusing on incremental travelers and higher yields

Travel Arrangements 馃嚭馃嚫 San Diego 293 2010
17
Mercatomercato.com

Mercato enables online ordering and delivery of fresh local groceries from specialty food shops, offering individual items, curated lists, and recipe ingredients

Technology, Information and Internet 馃嚭馃嚫 San Diego 219 2015
18
Rock West Compositesrockwestcomposites.com

Designs, engineers, and manufactures quality composite products using various techniques, ensuring superior value and customer satisfaction with experienced personnel.

Aviation and Aerospace Component Manufacturing 馃嚭馃嚫 San Diego 209 2009
19
Steren Solutionssterensolutions.com

This company provides innovative electronics connectivity solutions, manufacturing over 3,000 products for broadband, telco, and consumer electronics distributors, ensuring quality and customer satisfaction.

Appliances, Electrical, and Electronics Manufacturing 馃嚭馃嚫 San Diego 162 1956
20
InvivoGeninvivogen.com

Specialists in cell culture engineering and innate immunity, providing innovative reagents and tools for cutting-edge research globally

Biotechnology Research 馃嚭馃嚫 San Diego 130 1977
21
Chosen Foodschosenfoods.com

Dedicated to promoting health and sustainability by offering products made with 100% pure avocado oil to replace unhealthy fats

Wholesale Food and Beverage 馃嚭馃嚫 San Diego 114 2011
22
NanogenNanogen.com

Develops diagnostic products for improved patient care, focusing on cardiovascular disease and infectious diseases with molecular diagnostic kits and rapid test kits for point-of-care use

Biotechnology Research 馃嚭馃嚫 San Diego 74 1993
23
OZ Biosciencesozbiosciences.com

Product development company specializing in advanced delivery systems for bioactive materials such as DNA, siRNA, proteins, and antibodies to accelerate scientific discoveries

Biotechnology Research 馃嚭馃嚫 San Diego 22 2003
24
Biotonebiotone.com

Manufacturer of professional massage oils, cremes, lotions, gels, and spa body products for high quality therapeutic use.

Chemical Manufacturing 馃嚭馃嚫 San Diego 13 n/a
25
Achilles Coffee Roastersachillescoffeeroasters.com

Local micro coffee roaster with two San Diego locations, offering a variety of roasts and origins for pour over, along with breakfast sandwiches and vegan/gluten-free options

Food and Beverage Services 馃嚭馃嚫 San Diego 9 n/a
26
ZUMBAR COFFEE & TEA, LLCzumbarcoffee.com

A boutique coffee roaster in San Diego with retail cafes in Sorrento Valley and Cardiff, offering some of the finest coffees globally

Restaurants 馃嚭馃嚫 San Diego 5 n/a
27
Manzanita Roasting Company, in Sunny San Diego, CAmanzanitaroasting.com

Specializing in fresh artisan roasted coffee in San Diego, offering wholesale and retail coffee beans sourced, roasted, and tested at Bernardo Winery

Restaurants 馃嚭馃嚫 San Diego 4 2014

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 2, 2026.

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