This selection of Philadelphia-based companies highlights the city's significant presence in healthcare and related sectors. It includes major hospital systems and academic medical centers, as well as educational institutions and non-profit organizations. Many of these are large, established entities, reflecting a mature and comprehensive healthcare landscape.
Key organizations include Penn Medicine, University of Pennsylvania Health System, a leading academic medical center, and Jefferson Health, dedicated to clinical care and health education. Children's Hospital of Philadelphia specializes in pediatric care, while RITE AID is a large retail pharmacy chain. University of Pennsylvania is a renowned Ivy League university with a medical school. A notable pattern is the concentration of large hospital networks and academic institutions, many of which have been established for over a century.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
RITE AIDriteaid.com
A full-service pharmacy offering retail and delivery pharmacy services, health coaching, and disease management solutions through its subsidiaries Operates nationwide |
28,846 | |||
| 2 |
University of Pennsylvaniaupenn.edu
Renowned Ivy League university with 12 schools offering a wide range of programs including arts, sciences, engineering, business, and medicine |
22,558 | |||
| 3 |
Penn Medicine, University of Pennsylvania Health Systempennmedicine.org
Leading academic medical center combining cutting-edge research, comprehensive patient care, and education to improve health and transform lives regionally. |
21,979 | |||
| 4 |
Jefferson Healthjeffersonhealth.org
This company is dedicated to providing excellent clinical care, educating future health professionals, and advancing research in health sciences |
18,520 | |||
| 5 |
Children's Hospital of Philadelphiachop.edu
Specialized pediatric hospital providing exceptional patient care, pioneering medical research, and training future pediatric healthcare professionals. |
18,042 | |||
| 6 |
Temple Health – Temple University Health Systemtemplehealth.org
Temple Health provides advanced research and clinical care, offering innovative treatments through renowned physicians, nurses, and researchers in various medical facilities and practices |
5,770 | |||
| 7 |
Einstein Healthcare Networkjeffersonhealth.org
Healthcare network serving Philadelphia and Montgomery County, offering comprehensive medical services and patient care across multiple facilities. |
3,812 | |||
| 8 |
Fox Chase Cancer Centerfoxchase.org
Dedicated cancer hospital with expert multidisciplinary teams advancing prevention, diagnosis, treatment, and survivorship through pioneering research and clinical care. |
2,146 | |||
| 9 |
Resources for Human Developmentrhd.org
A human services organization based in Philadelphia empowering vulnerable populations to achieve independence through innovative programs across 14 states |
1,782 | |||
| 10 |
Philadelphia College of Osteopathic Medicinepcom.edu
A not-for-profit institution providing education in healthcare fields with a focus on whole person care, research, and community service |
1,611 | |||
| 11 |
Aria - Jefferson Healthjeffersonhealth.org
A leading healthcare provider in Northeast Philadelphia and Lower Bucks County, offering community hospitals, outpatient centers, and primary care physicians to improve lives |
1,421 | |||
| 12 |
St. Christopher's Hospital for Childrentowerhealth.org
A renowned pediatric care provider in Philadelphia offering exceptional services and nationally recognized programs for children worldwide since 1875 |
1,364 | |||
| 13 |
Rothman Orthopaedicsrothmanortho.com
Leading orthopaedic practice offering high-quality treatment for various musculoskeletal issues with top specialists, recognized for excellence, team physicians for professional sports teams, and urgent care services available |
1,269 | |||
| 14 |
JEVS Human Servicesjevshumanservices.org
This organization provides a wide range of services including skills training, vocational rehabilitation, recovery services, and more to support individuals in need |
1,124 | |||
| 15 |
Hahnemann University HospitalHahnemannHospital.com
Academic medical center offering high-quality care in kidney/liver transplantation, OB/GYN, oncology, robotic surgery, pediatrics, bariatric surgery, neurology, orthopedics, urology, and more |
1,019 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
City of Philadelphia – Department of Public Healthphila.gov
Promoting public health for all Philadelphians through services, policies, and partnerships to create a healthy environment for living, working, and playing |
827 | |||
| 17 |
Nazareth Hospitaltrinityhealthma.org
Providing compassionate healthcare services to Northeast Philadelphia and surrounding areas for over 75 years with a focus on personal care |
825 | |||
| 18 | 
St Joes Hospital
A hospital & health care company located in Philadelphia, Pennsylvania, providing medical services and care to the community |
804 | |||
| 19 |
Public Health Management Corporationphmc.org
A nonprofit public health institute in the Greater Philadelphia region, providing outreach, education, research, planning, and direct services to improve community health |
748 | |||
| 20 |
365 Health Services365healthservices.com
A home healthcare organization located in the Greater Philadelphia area, providing a range of health services to clients |
724 | |||
| 21 |
Jefferson Moss-Magee Rehabilitationjeffersonhealth.org
Provider of physical and cognitive rehabilitation in Philadelphia region, offering lifetime programs for individuals with spinal cord injury, brain injury, stroke, and more |
603 | |||
| 22 |
Drexel University's College of Nursing and Health Professionsdrexel.edu
Educational institution specializing in nursing and health professions, with a focus on technology, evidence-based programs, research, and community-based practice initiatives |
588 | |||
| 23 |
Elixirelixirsolutions.com
Pharmacy benefits and services company offering adjudication platform, mail/specialty pharmacies, population health services, and prescription discount programs for cost savings and better health outcomes |
584 | |||
| 24 |
Wills Eye Hospitalwillseye.org
A global leader in eye disease treatment, providing top-notch care, cutting-edge technology, and advanced surgical capabilities to patients worldwide since 1832 |
556 | |||
| 25 |
Northeast Treatment Centersnetcenters.org
Non-profit organization in Greater Philadelphia providing behavioral health, social services, and foster care, with a focus on individualized, quality-driven support |
514 | |||
| 26 |
COMHAR, Inc.comhar.org
Nonprofit organization providing integrated behavioral health, intellectual disabilities, HIV/AIDS, and home health services to diverse populations through various community settings |
506 | |||
| 27 |
Enclara Pharmaciaenclarapharmacia.com
A leading pharmacy services provider for hospice care, offering medication access, clinical expertise, and technology to enhance quality of life |
462 | |||
| 28 |
Cardiology Consultants of Philadelphiaccpdocs.com
A cardiology practice in Greater Philadelphia focused on providing complete, compassionate diagnoses and treatments through a tightly integrated team approach |
461 | |||
| 29 |
The Renfrew Centerrenfrewcenter.com
Leader in eating disorder treatment since 1985, offering residential, day, outpatient, and virtual services with evidence-based therapy to support recovery and healing |
452 | |||
| 30 |
FullBloomfullbloom.org
FullBloom provides education and behavioral health solutions to improve outcomes for children and families through evidence-based programs and professional development |
450 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 13, 2026.
More company lists in Philadelphia
- The largest companies in Philadelphia 552
- Multinational companies in Philadelphia 76
- Education providers in Philadelphia 72
- Professional services firms in Philadelphia 72
- Retail chains in Philadelphia 51
- Critical infrastructure operators in Philadelphia 41
- Financial services firms in Philadelphia 38
- Hospitals and Health Care companies in Philadelphia 38
- Companies with in-house R&D in Philadelphia 35
- Higher Education companies in Philadelphia 35
- Consulting firms in Philadelphia 34
- Hotel and hospitality groups in Philadelphia 28
The same list elsewhere in United States
- Healthcare providers in the United States 5,810
- Healthcare providers in California 569
- Healthcare providers in New York State 494
- Healthcare providers in Texas 408
- Healthcare providers in Florida 361
- Healthcare providers in Pennsylvania 264
- Healthcare providers in Illinois 262
- Healthcare providers in Massachusetts 213
- Healthcare providers in Ohio 181
- Healthcare providers in Tennessee 180
- Healthcare providers in Michigan 157
- Healthcare providers in North Carolina 153
- Healthcare providers in New Jersey 151
- Healthcare providers in Georgia 148
- Healthcare providers in Washington State 136
- Healthcare providers in Colorado 126
- Healthcare providers in Alabama 124
- Healthcare providers in Indiana 123
- Healthcare providers in Arizona 122
- Healthcare providers in Virginia 121
- Healthcare providers in Minnesota 120
- Healthcare providers in Missouri 118
- Healthcare providers in Maryland 105
- Healthcare providers in New York 155