This list features large operators of critical infrastructure in Philadelphia, primarily in healthcare and telecommunications. Key players include Comcast, a major provider of broadband and entertainment, and Penn Medicine, a leading academic medical center. Other significant entities are Jefferson Health, focused on clinical care and research, and Children's Hospital of Philadelphia, a specialized pediatric hospital. These are well-established organizations, with many founded in the late 19th or mid-20th century.
The data shows a strong concentration of healthcare providers, with several large hospital systems such as Temple Health and Einstein Healthcare Network. Beyond healthcare, other critical services are represented by organizations like Southeastern Pennsylvania Transportation Authority (SEPTA) for public transit, PECO for utilities, and Philadelphia Gas Works for natural gas.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Comcastcomcast.com
Delivering broadband, mobile, and video products, along with entertainment, sports, news, and theme park experiences; driven by passionate creators and innovators |
189,000 | |||
| 2 |
Penn Medicine, University of Pennsylvania Health Systempennmedicine.org
Leading academic medical center combining cutting-edge research, comprehensive patient care, and education to improve health and transform lives regionally. |
21,979 | |||
| 3 |
Jefferson Healthjeffersonhealth.org
This company is dedicated to providing excellent clinical care, educating future health professionals, and advancing research in health sciences |
18,520 | |||
| 4 |
Children's Hospital of Philadelphiachop.edu
Specialized pediatric hospital providing exceptional patient care, pioneering medical research, and training future pediatric healthcare professionals. |
18,042 | |||
| 5 |
Comcast Businessbusiness.comcast.com
A technology solutions provider offering connectivity, networking, cybersecurity, and communications solutions to businesses of all sizes, with a focus on driving innovation and growth |
9,292 | |||
| 6 |
Temple Health โ Temple University Health Systemtemplehealth.org
Temple Health provides advanced research and clinical care, offering innovative treatments through renowned physicians, nurses, and researchers in various medical facilities and practices |
5,770 | |||
| 7 |
Southeastern Pennsylvania Transportation Authority (SEPTA)septa.org
A major public transit system in Southeastern Pennsylvania offering bus, subway, trolley, Regional Rail, paratransit, and shared ride services across multiple counties |
3,982 | |||
| 8 |
Xfinityxfinity.com
Revolutionizing connectivity with the Xfinity 10G Network, leading the way into the future of high-speed internet services |
3,979 | |||
| 9 |
Einstein Healthcare Networkjeffersonhealth.org
Healthcare network serving Philadelphia and Montgomery County, offering comprehensive medical services and patient care across multiple facilities. |
3,812 | |||
| 10 | 2,481 | ||||
| 11 |
Fox Chase Cancer Centerfoxchase.org
Dedicated cancer hospital with expert multidisciplinary teams advancing prevention, diagnosis, treatment, and survivorship through pioneering research and clinical care. |
2,146 | |||
| 12 |
Aria - Jefferson Healthjeffersonhealth.org
A leading healthcare provider in Northeast Philadelphia and Lower Bucks County, offering community hospitals, outpatient centers, and primary care physicians to improve lives |
1,421 | |||
| 13 |
St. Christopher's Hospital for Childrentowerhealth.org
A renowned pediatric care provider in Philadelphia offering exceptional services and nationally recognized programs for children worldwide since 1875 |
1,364 | |||
| 14 |
Philadelphia Gas Workspgworks.com
provides natural gas energy services and solutions to over 500,000 residential and commercial customers in Philadelphia city |
1,047 | |||
| 15 |
Philadelphia Water Departmentwater.phila.gov
This company provides integrated water, wastewater, and stormwater services to the City of Philadelphia's 15 million residents, focusing on high-quality water supply and watershed management |
863 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
Federal Reserve Bank of Philadelphiaphiladelphiafed.org
Implement monetary policy, supervise banks, provide financial services to institutions and government One of 12 regional Reserve Banks in Federal Reserve System |
852 | |||
| 17 |
Nazareth Hospitaltrinityhealthma.org
Providing compassionate healthcare services to Northeast Philadelphia and surrounding areas for over 75 years with a focus on personal care |
825 | |||
| 18 |
Philadelphia Fire Departmentphila.gov
The company provides fire protection, emergency medical services, and specialized divisions to investigate fires and protect Philadelphia International Airport |
722 | |||
| 19 |
Police and Fire Federal Credit Unionpffcu.org
A financial organization focused on exceptional member service, offering loans, deposits, competitive salaries, benefits, and growth opportunities for motivated professionals |
669 | |||
| 20 |
Jefferson Moss-Magee Rehabilitationjeffersonhealth.org
Provider of physical and cognitive rehabilitation in Philadelphia region, offering lifetime programs for individuals with spinal cord injury, brain injury, stroke, and more |
603 | |||
| 21 |
Xfinity Communitiesxfinity.com
Provides fast, reliable internet and entertainment services to multiple communities, ensuring connectivity and 24/7 customer support. |
565 | |||
| 22 |
Wills Eye Hospitalwillseye.org
A global leader in eye disease treatment, providing top-notch care, cutting-edge technology, and advanced surgical capabilities to patients worldwide since 1832 |
556 | |||
| 23 |
Conrailconrail.com
Conrail provides services for CSX Corporation and Norfolk Southern Corporation, offering transportation solutions to meet their logistics needs |
527 | |||
| 24 |
American Heritage Credit Unionamericanheritagecu.org
A member-owned financial cooperative offering tailored financial solutions, serving over 300,000 members through 35+ locations in the Greater Philadelphia area |
518 | |||
| 25 |
The Renfrew Centerrenfrewcenter.com
Leader in eating disorder treatment since 1985, offering residential, day, outpatient, and virtual services with evidence-based therapy to support recovery and healing |
452 | |||
| 26 |
GSPP Rehabilitationpennrehab.org
Innovative rehabilitation services for a wide range of conditions, offering inpatient and outpatient care, guided by expert clinical staff shaping future research |
445 | |||
| 27 |
Chestnut Hill Hospital - Temple Healthtemplehealth.org
A community-based teaching hospital in Chestnut Hill, Philadelphia, offering a wide range of diagnostic, treatment services, and specialties with board-certified physicians |
432 | |||
| 28 |
Beneficial Bankwsfsbank.com
This company has transitioned to WSFS Bank They provide financial services and have a LinkedIn page at https://wwwlinkedincom/company/wsfs-bank |
420 | |||
| 29 |
Thomas Jefferson University Hospitaljeffersonhealth.org
The company provides excellent clinical and compassionate care for patients in the Philadelphia region through a partnership with a university |
403 | |||
| 30 |
Philadelphia Parking Authorityphilapark.org
The company manages parking and transportation services in Philadelphia, including street parking, airport parking, garages, red-light camera enforcement, and taxi regulation |
367 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Philadelphia
- The largest companies in Philadelphia 552
- Multinational companies in Philadelphia 76
- Education providers in Philadelphia 72
- Professional services firms in Philadelphia 72
- Healthcare providers in Philadelphia 60
- Retail chains in Philadelphia 51
- Financial services firms in Philadelphia 38
- Hospitals and Health Care companies in Philadelphia 38
- Companies with in-house R&D in Philadelphia 35
- Higher Education companies in Philadelphia 35
- Consulting firms in Philadelphia 34
- Hotel and hospitality groups in Philadelphia 28
The same list elsewhere in United States
- Critical infrastructure operators in the United States 5,801
- Critical infrastructure operators in Texas 579
- Critical infrastructure operators in California 483
- Critical infrastructure operators in New York State 379
- Critical infrastructure operators in Florida 321
- Critical infrastructure operators in Illinois 241
- Critical infrastructure operators in Pennsylvania 225
- Critical infrastructure operators in Alabama 186
- Critical infrastructure operators in North Carolina 171
- Critical infrastructure operators in Massachusetts 165
- Critical infrastructure operators in Ohio 153
- Critical infrastructure operators in Michigan 150
- Critical infrastructure operators in Washington State 149
- Critical infrastructure operators in Colorado 137
- Critical infrastructure operators in Tennessee 132
- Critical infrastructure operators in Virginia 131
- Critical infrastructure operators in New Jersey 130
- Critical infrastructure operators in Indiana 129
- Critical infrastructure operators in Georgia 126
- Critical infrastructure operators in Missouri 120
- Critical infrastructure operators in Minnesota 115
- Critical infrastructure operators in Wisconsin 115
- Critical infrastructure operators in Houston 161
- Critical infrastructure operators in New York 139