List of critical infrastructure operators in Ohio (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	Cleveland Clinic my.clevelandclinic.org A not-for-profit academic medical center in Ohio, offering clinical care, research, and education with multiple facilities worldwide	Hospitals and Health Care	🇺🇸 Cleveland	49,624	n/a
2	Bon Secours Mercy Health bsmhealth.org Operates 48 hospitals and thousands of providers across seven states and Ireland, focusing on quality, safety, and cost-effective healthcare delivery.	Hospitals and Health Care	🇺🇸 Cincinnati	32,495	n/a
3	Fifth Third Bank 53.com Diversified financial services company providing commercial and branch banking, consumer lending, and wealth management through a network of regional financial centers and ATMs.	Financial Services	🇺🇸 Cincinnati	25,396	n/a
4	KeyBank key.com Provides investment management, retail and commercial banking, consumer finance, and investment banking products to individuals and businesses nationwide.	Banking	🇺🇸 Cleveland	23,230	1849
5	University Hospitals uhhospitals.org Integrated healthcare provider in northern Ohio, offering hospital services, outpatient facilities, physician offices, and leading research programs.	Hospitals and Health Care	🇺🇸 Cleveland	20,700	1866
6	Huntington National Bank huntington.com Regional financial services holding company offering banking, payments, wealth management, and risk products for individuals, businesses, and municipalities through numerous branches and community initiatives.	Banking	🇺🇸 Columbus	20,037	1866
7	Marathon Petroleum Corporation marathonpetroleum.com Operates the nation's largest refining system, markets petroleum products, and manages midstream assets for gathering, processing, and transportation.	Oil and Gas	🇺🇸 Findlay	17,048	1887
8	The Ohio State University Wexner Medical Center wexnermedical.osu.edu Academic medical center providing personalized patient care, medical education, research innovation, and extensive healthcare services across multiple specialties.	Hospitals and Health Care	🇺🇸 Columbus	15,993	1834
9	OhioHealth ohiohealth.com A nationally recognized, not-for-profit health system with 14 hospitals and 200+ care sites, focused on improving health and wellbeing	Hospitals and Health Care	🇺🇸 Columbus	15,284	1891
10	Mercy Health mercy.com Provides compassionate, high-quality healthcare across Ohio and Kentucky with a large network of employees and numerous care points.	Hospitals and Health Care	🇺🇸 Cincinnati	14,380	n/a
11	American Electric Power aep.com The company is focused on reducing carbon footprint, empowering communities, developing workforce, shifting to clean energy sources, and building stronger communities for the future	Utilities	🇺🇸 Columbus	13,166	n/a
12	Nationwide Children's Hospital nationwidechildrens.org Provides advanced pediatric medical care, conducts leading research, trains specialists, and offers specialized programs in heart, cancer, and neonatology.	Hospitals and Health Care	🇺🇸 Columbus	12,575	1892
13	ProMedica promedica.org A not-for-profit health organization offering acute and ambulatory care, insurance, post-acute services, academic programs, and various healthcare facilities and services	Hospitals and Health Care	🇺🇸 Toledo	9,864	1986
14	Worldpay worldpay.com Global payment processing solutions enabling businesses to accept payments worldwide in-person and online, in multiple currencies and markets, offered by leading technology provider	Financial Services	🇺🇸 Cincinnati	8,838	1993
15	Kettering Health ketteringhealth.org A faith-based healthcare system providing medical care, outpatient services, and health science education through dedicated providers and medical professionals	Hospitals and Health Care	🇺🇸 Kettering	8,249	1964
16	TriHealth trihealth.com A comprehensive healthcare provider offering a full range of services, including prevention, wellness, education, and acute care through multiple locations in Cincinnati	Hospitals and Health Care	🇺🇸 Cincinnati	7,070	1995
17	UC Health uchealth.com Top clinicians and researchers providing world-class, compassionate healthcare through advanced clinical services, teaching, innovation, and research in Cincinnati.	Hospitals and Health Care	🇺🇸 Cincinnati	6,134	n/a
18	Summa Health summahealth.org Integrated healthcare system in Ohio with hospitals, health centers, health plan, research, and foundations, known for patient care excellence and innovative approaches	Hospitals and Health Care	🇺🇸 Akron	5,630	1989
19	US Acute Care Solutions usacs.com A national leader in physician-owned integrated acute care services, providing high-quality care to millions of patients annually at over 500 programs	Hospitals and Health Care	🇺🇸 Canton	5,376	2015
20	The MetroHealth System (Cleveland, OH)metrohealth.org Healthcare system focusing on community health by addressing social determinants, providing integrated care, and emphasizing disease prevention alongside treatment	Hospitals and Health Care	🇺🇸 Cleveland	5,352	1837
21	The Christ Hospital Health Network thechristhospital.com Regional healthcare system providing integrated, individualized care through extensive physician network, advanced specialties, and patient-focused wellness services in Cincinnati.	Hospitals and Health Care	🇺🇸 Cincinnati	5,300	1889
22	Akron Children's akronchildrens.org Largest pediatric healthcare system in Northern Ohio providing compassionate, high-quality care through hospitals, regional centers, and specialty locations.	Hospitals and Health Care	🇺🇸 Akron	5,264	1890
23	Western & Southern Financial Group westernsouthern.com Group of companies providing life insurance, investment advisory, brokerage services, and real estate management across multiple sectors.	Financial Services	🇺🇸 Cincinnati	5,199	1888
24	R+L Carriers rlcarriers.com A family-owned global freight transportation and logistics company based in the US, offering LTL, truckload, expedited shipping, and international supply chain services	Truck Transportation	🇺🇸 Wilmington	5,102	1965
25	Premier Health Partners premierhealth.com Regional healthcare system offering hospital care, emergency services, outpatient clinics, home health, mental health, and substance abuse treatment in Southwest Ohio.	Hospitals and Health Care	🇺🇸 Dayton	4,992	1995
26	The Cincinnati Insurance Companies cinfin.com Property casualty insurance group offering business, home, auto, life, and disability insurance through independent agencies across 46 states.	Insurance	🇺🇸 Fairfield	4,931	1950
27	Mount Carmel Health System mountcarmelhealth.com Four hospitals, emergency centers, surgery centers, outpatient facilities, physician offices, and community outreach providing personalized, people-centered healthcare in central Ohio.	Hospitals and Health Care	🇺🇸 Columbus	4,778	1886
28	Alliance Data breadfinancial.com Provider of financial services undergoing rebranding to Bread Financial, focusing on customer engagement and payment solutions.	Financial Services	🇺🇸 Columbus	3,989	n/a
29	City of Columbus columbus.gov A government entity in Columbus, Ohio, working to provide high-quality services, support economic development, and maintain vibrant neighborhoods for residents	Government Administration	🇺🇸 Columbus	3,819	1812
30	Aultman Health Foundation aultman.org Leading provider of healthcare services in Stark County since 1892, offering high-quality care, educational opportunities, wellness programs, and community support	Hospitals and Health Care	🇺🇸 Canton	3,276	n/a
31	Cleveland Clinic Akron General my.clevelandclinic.org A nonprofit healthcare organization providing medical, rehabilitation, wellness, and community health services ranked as one of the top hospitals in Ohio	Hospitals and Health Care	🇺🇸 Akron	2,783	1914
32	Dayton Children's Hospital childrensdayton.org Specialized pediatric hospital providing children in a 20-county area with comprehensive medical care through a dedicated team of physicians and staff	Hospitals and Health Care	🇺🇸 Dayton	2,751	n/a
33	Miami Valley Hospital premierhealth.com A leading regional healthcare provider offering maternity, emergency, air ambulance services, transplant units, oncology, cardiology, rehabilitation, and surgical services Visit website for more information	Hospitals and Health Care	🇺🇸 Dayton	2,637	1890
34	KeyBank Commercial key.com Full-service commercial and investment bank offering capital markets solutions, mortgage finance, equipment finance, public finance, and commercial payments for middle market clients.	Financial Services	🇺🇸 Cleveland	2,573	n/a
35	CommuniCare Health Services communicarehealth.com Provider of nursing, rehabilitation, and assisted living services in multiple states, focusing on creating caring communities where residents are treated like family	Hospitals and Health Care	🇺🇸 Blue Ash	2,493	1984
36	First Financial Bank bankatfirst.com Regional bank offering personalized financial services and community-focused banking with over 130 centers across five Midwestern states.	Banking	🇺🇸 Cincinnati	2,446	1863
37	altafiber altafiber.com A company with a history of serving communities through innovation is now focused on expanding fiber access to connect more people and businesses	Telecommunications	🇺🇸 Cincinnati	2,273	n/a
38	Adena Health System adena.org Healthcare organization in Ohio providing a wide range of specialty services with a focus on compassion, integrity, and excellence in caring for communities	Hospitals and Health Care	🇺🇸 Chillicothe	2,159	1895
39	Genesis Healthcare System genesishcs.org Integrated healthcare delivery system in Southeastern Ohio offering not-for-profit hospital services, specialized centers, physician network, and various outpatient care centers and affiliates	Hospitals and Health Care	🇺🇸 Zanesville	2,059	1901
40	Ohio Department of Transportation transportation.ohio.gov Maintaining large transportation networks to ensure safe movement of people and goods while improving system capacity and existing infrastructure across Ohio.	Transportation Programs	🇺🇸 Columbus	2,009	1905
41	Ohio State University Comprehensive Cancer Center-James Cancer Hospital & Solove Research Institute cancer.osu.edu Leading cancer research center and hospital focused on integrating research, education, and patient care to advance prevention, detection, and treatment Ranked among top in the nation	Hospitals and Health Care	🇺🇸 Columbus	1,970	n/a
42	Kenan Advantage Group thekag.com A leading North American tank truck transporter and logistics provider delivering energy commodities, renewable fuels, chemicals, food products, and more with a focus on safety and sustainability	Truck Transportation	🇺🇸 North Canton	1,774	1991
43	Blanchard Valley Health System bvhealthsystem.org A comprehensive health system in northwest Ohio offering a full continuum of care, employing over 3,000 associates and serving an eight county area	Hospitals and Health Care	🇺🇸 Findlay	1,658	1891
44	Southwest General Health Center swgeneral.com A non-profit hospital offering a wide range of medical services, state-of-the-art technology, and support programs with a commitment to excellence and compassion	Hospitals and Health Care	🇺🇸 Middleburg Heights	1,402	1920
45	Southern Ohio Medical Center somc.org A 248-bed hospital in Portsmouth, Ohio, providing emergency, surgical, and a wide range of healthcare services with a focus on safety, quality, and customer service	Hospitals and Health Care	🇺🇸 Portsmouth	1,294	n/a
46	Park National Bank parknationalbank.com Community banking with a focus on strong relationships, personalized service, flexible options, and a commitment to serving customers' financial goals with integrity	Banking	🇺🇸 Newark	1,280	1908
47	Licking Memorial Health Systems lmhealth.org A not-for-profit healthcare organization offering a range of quality patient care services, specialized medical services, and fundraising for future medical care improvement	Hospitals and Health Care	🇺🇸 Newark	1,276	1898
48	Holzer Health System holzer.org A healthcare system with a rich history, providing comprehensive services and advanced technology in south central Ohio, West Virginia, and Kentucky	Hospitals and Health Care	🇺🇸 Gallipolis	1,191	1909
49	Fairfield Medical Center fmchealth.org A vibrant healthcare organization providing exceptional care, dedicated to creating a positive impact on the community through personal growth and unparalleled employee support	Hospitals and Health Care	🇺🇸 Lancaster	1,187	1916
50	Federal Reserve Bank of Cleveland clevelandfed.org Formulates monetary policy, supervises banks, provides payment services, and supports economic stability in the Fourth Federal Reserve District.	Banking	🇺🇸 Cleveland	1,176	1914
51	American Modern Insurance Group policyholders.amig.com specialty insurance solutions for classic cars, motorcycles, boats, rental properties, vacant homes, vacation homes, and manufactured homes	Insurance	🇺🇸 Cincinnati	1,158	1938
52	KeyBanc Capital Markets key.com A national platform with over 800 professionals, providing capital, equity research, and deep industry expertise across seven sectors for clients' success	Investment Banking	🇺🇸 Cleveland	1,107	1924
53	STG Logistics stgusa.com Nationwide logistics provider offering intermodal, drayage, warehousing, transloading, and final mile transportation with extensive facility network.	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Dublin	1,106	n/a
54	Firelands Health firelands.com A comprehensive healthcare provider offering a 287-bed medical center, behavioral health services, rehabilitation, and a physician group	Hospitals and Health Care	🇺🇸 Sandusky	1,092	1873
55	Avita Health System avitahealth.org A nonprofit health care system in North Central Ohio with hospitals, clinics, and providers dedicated to improving patient experience and community wellbeing	Hospitals and Health Care	🇺🇸 Galion	1,066	2011
56	Wright-Patt Credit Union wpcu.coop This company is a member-owned credit union offering a range of financial services and products through a registered broker-dealer	Financial Services	🇺🇸 Beavercreek	1,024	1932
57	ABX Air, Inc.abxair.com A cargo airline operating Boeing 767 freighters for express cargo routes globally Offers charter services, dispatch training, flight training, and simulator time	Airlines and Aviation	🇺🇸 Wilmington	977	1980
58	City of Toledo toledo.oh.gov The organization focuses on enhancing the quality of life for residents, implementing forward-thinking policies, and driving economic development within the city	Government Administration	🇺🇸 Toledo	966	n/a
59	Trinity Health System trinityhealth.com A healthcare system committed to improving health, advancing social justice, and providing comprehensive services to the community with compassion and excellence	Hospitals and Health Care	🇺🇸 Steubenville	956	n/a
60	FirstMerit Bank huntington.com A banking institution that was previously FirstMerit Bank but has now transitioned to Huntington National Bank, providing news and updates	Financial Services	🇺🇸 Akron	937	1845
61	Lake Health uhhospitals.org Healthcare provider in Northeast Ohio now part of a larger health system with numerous hospitals, health centers, and physician offices	Hospitals and Health Care	🇺🇸 Concord Twp.	927	1902
62	Heartland Hospice Services gentivahs.com Heartland Hospice Services provides hospital and health care services in Lima, Ohio, focusing on compassionate end-of-life care for patients	Hospitals and Health Care	🇺🇸 Lima	922	n/a
63	CommuteAir commuteair.com Regional airline operating flights for United Airlines with a fleet of over 60 Embraer ERJ145 aircraft, connecting people to United's global network	Airlines and Aviation	🇺🇸 Cleveland	904	1989
64	Lima Memorial Health System limamemorial.org A leading health care system in west central Ohio offering a wide range of high-quality medical services and specialized care	Hospitals and Health Care	🇺🇸 Lima	889	1899
65	Ohio Living ohioliving.org A leading not-for-profit organization providing senior living, healthcare, hospice, and charitable services to over 10 million Ohio residents	Hospitals and Health Care	🇺🇸 Westerville	884	1922
66	Central Ohio Primary Care copcp.com A leading primary care provider in Central Ohio, focused on offering the best patient care through innovative practices and services	Hospitals and Health Care	🇺🇸 Westerville	844	1996
67	Air Transport International, Inc.airtransport.cc Passenger and cargo airline offering worldwide charter, scheduled flights, and ACMI wet lease services with global operational presence.	Aviation and Aerospace Component Manufacturing	🇺🇸 Wilmington	822	1978
68	City of Cleveland - City Hall clevelandohio.gov Providing high-quality city services, prioritizing neighborhoods, enhancing safety, and modernizing city operations to benefit residents and businesses.	Government Administration	🇺🇸 Cleveland	784	n/a
69	Ohio National Financial Services constellationinsurance.com A financial services company offering insurance protection, wealth accumulation options, and retirement solutions through a network of agencies and distribution organizations	Financial Services	🇺🇸 Cincinnati	753	1909
70	Greater Cleveland RTA riderta.com Large public transit agency providing bus, rapid rail, trolley, and paratransit services for thousands of daily passengers across Cuyahoga County, Ohio.	Urban Transit Services	🇺🇸 Cleveland	744	1974
71	Mercy Medical Center, Canton, Ohio cantonmercy.org Faith-based medical center with 476-bed hospital and multiple outpatient locations, part of Cleveland Clinic health system, with strong safety ratings	Hospitals and Health Care	🇺🇸 Canton	744	1908
72	Union Savings Bank usavingsbank.com A leading mortgage lender focused on affordable home financing, providing personal attention, low-cost loans, and timely approvals to help customers achieve their dream homes	Banking	🇺🇸 Cincinnati	743	1904
73	Mercy Health (Youngstown)mercy.com Integrated health system in Ohio's Mahoning Valley, offering nationally ranked care across physician offices, hospitals, home care, long-term care, and hospice services	Hospitals and Health Care	🇺🇸 Youngstown	737	1911
74	National Interstate Insurance Company natl.com A leading provider of insurance solutions for commercial transportation industries nationwide, offering innovative products, superior financial strength, and personalized support	Insurance	🇺🇸 Richfield	733	n/a
75	Alliance Data Card Services breadfinancial.com Bread Financial provides card services previously offered by Alliance Data, offering financial solutions and information through their website and social media	Financial Services	🇺🇸 Columbus	712	n/a
76	Knox Community Hospital kch.org A not-for-profit hospital in Mount Vernon, Ohio, committed to improving patient service, technology, and facilities for the community's benefit	Hospitals and Health Care	🇺🇸 Mount Vernon	710	n/a
77	Alternate Solutions Health Network ashealthnet.com Specializing in post-acute care solutions, we partner with health systems to improve quality outcomes and financial performance through centralized operations and innovative software	Hospitals and Health Care	🇺🇸 Kettering	710	1999
78	Signature Health, Inc.signaturehealthinc.org A Federally Qualified Health Center providing mental health, addiction recovery, primary care, pharmacy, and lab services to patients of all ages in Northeast Ohio	Mental Health Care	🇺🇸 Kirtland	707	1993
79	Hospice of the Western Reserve hospicewr.org Provider of hospice and palliative care services, along with bereavement support, throughout Northern Ohio regardless of ability to pay	Hospitals and Health Care	🇺🇸 Cleveland	679	1978
80	Health Alliance uchealth.com UC Health provides world-class medical care in Cincinnati, backed by top clinicians and researchers from the University of Cincinnati College of Medicine	Hospitals and Health Care	🇺🇸 Cincinnati	672	2009
81	The Toledo Clinic toledoclinic.com A large multi-specialty physician group in Toledo offering a wide range of medical services including radiology, laboratory, pharmacy, and outpatient surgery	Hospitals and Health Care	🇺🇸 Toledo	668	1926
82	Third Federal thirdfederal.com A company committed to love, trust, respect, and excellence, helping people achieve homeownership and financial security while creating value for communities and stockholders	Banking	🇺🇸 Cleveland	667	1938
83	Fisher-Titus Medical Center fishertitus.org An independent not-for-profit community health system in Ohio, providing high-quality medical care, digital technology, and personalized services to residents	Hospitals and Health Care	🇺🇸 Norwalk	656	1917
84	Fairview Hospital my.clevelandclinic.org Faith-based community hospital with 517 beds, offering comprehensive healthcare services including Level II Trauma Center, Cancer Center, Heart Center, and Surgery	Hospitals and Health Care	🇺🇸 Cleveland	647	n/a
85	KeyBank Real Estate Capital key.com A national finance platform specializing in commercial and multifamily real estate, offering a range of services including construction loans, mortgages, and agency financing solutions	Banking	🇺🇸 Cleveland	645	n/a
86	Western Reserve Hospital westernreservehospital.org Physician-owned hospital in Northeast Ohio offering high quality healthcare services, empowering physicians to drive delivery and prioritize patient satisfaction	Hospitals and Health Care	🇺🇸 Cuyahoga Falls	617	2009
87	Rainbow Babies and Children's Hospital uhhospitals.org Specialized hospital focused on providing healthcare services to babies and children, with a commitment to excellence and compassionate care	Hospitals and Health Care	🇺🇸 Cleveland	606	n/a
88	UToledo Health health.utoledo.edu public research university providing diverse services, flexible work schedules, professional growth opportunities, and a healthy work-life balance	Hospitals and Health Care	🇺🇸 Toledo	602	1964
89	St Ritas Medical Center A hospital and health care company located in Delphos, Ohio, providing medical services and care to patients in the United States	Hospitals and Health Care	🇺🇸 Delphos	588	n/a
90	Hospice of Northwest Ohio hospicenwo.org The company provides specialized hospice care for terminally ill patients and their families in Northwest Ohio and Southeast Michigan	Hospitals and Health Care	🇺🇸 Perrysburg	586	1981
91	Central Ohio Transit Authority (COTA)cota.com Providing affordable transit services across multiple counties, including paratransit for seniors and disabled, enhancing community mobility and opportunity.	Truck Transportation	🇺🇸 Columbus	571	1974
92	Farmers National Bank of Canfield farmersbankgroup.com A diversified financial services company with over $50 billion in banking assets, offering commercial and retail banking, trust services, and insurance	Banking	🇺🇸 Canfield	417	1887
93	Community Blood Center solvita.org The company collects blood from volunteer donors to meet patient transfusion needs and distributes blood products and tissue to hospitals	Hospitals and Health Care	🇺🇸 Dayton	340	n/a
94	Citizens Bank, now part of FirstMerit Bank, N.A.firstmerit.com A diversified financial services company offering banking and other financial services through multiple affiliates in the Midwest and Northeast regions	Banking	🇺🇸 Akron	298	1845
95	Hoxworth Blood Center hoxworth.org A nonprofit blood center serving hospitals in 18 counties by collecting over 90,000 units of blood annually to save lives	Non-profit Organizations	🇺🇸 Cincinnati	229	1938
96	State Bank yourstatebank.com Diversified financial services holding company with a full range of services, including wealth management, private client services, mortgage banking, and lending	Banking	🇺🇸 Defiance	202	1902
97	Directions Credit Union directionscu.org A trusted financial institution offering a complete range of services to members, with a focus on personalized guidance, competitive rates, and community involvement	Financial Services	🇺🇸 Toledo	191	1953
98	UWL shipuwl.com Global 3PL and freight forwarder offering a range of logistics services including ocean/air freight, customs brokerage, warehousing, and supply chain visibility solutions	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Cleveland	168	2007
99	Fayette County Memorial Hospital fcmh.org A community-based non-profit hospital providing advanced healthcare services and managed in partnership with Mount Carmel Health System	Hospitals and Health Care	🇺🇸 Washington Court House	164	1944
100	Laurel Road laurelroad.com A digital banking platform tailored for healthcare and business professionals, offering banking solutions, student loan refinancing, mortgages, personal loans, and more	Financial Services	🇺🇸 Cleveland	65	2006

Turn this list into pipeline

Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.

Build your own list, free

How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

List of critical infrastructure operators in Ohio

Turn this list into pipeline

How this list is built

More company lists in Ohio

The same list elsewhere in United States