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56 leading Hospitals and Health Care companies in South Carolina

Tamtam tracks 56 Hospitals and Health Care companies headquartered in South Carolina. This list ranks all of them by number of employees on LinkedIn, led by Medical University of South Carolina, Prisma Health and MUSC Health. Their median headcount is 412. Half of them were founded in 1991 or later. The most common headquarters are Charleston (14), Columbia (11) and Greenville (6).

๐Ÿ‡บ๐Ÿ‡ธ South Carolina56 companiesUpdated Oct 24, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
Medical University of South Carolinamusc.edu

Public institution focused on educating healthcare professionals, conducting biomedical research, and providing comprehensive healthcare services in South Carolina and beyond.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 15,845 1824
2
Prisma Healthcareers.prismahealth.org

largest nonprofit health system in South Carolina, serving over 1.2 million patients with quality care and improved access.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenville 14,555 2017
3
MUSC Healthmuschealth.org

A healthcare system based in South Carolina, providing high-quality patient care, education for healthcare providers, and groundbreaking research and innovation

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 5,606 1824
4
Spartanburg Regional Healthcare Systemspartanburgregional.com

Comprehensive healthcare services across multiple hospital campuses, cancer care centers, outpatient surgery, trauma center, and extensive physician network.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Spartanburg 4,897 1921
5
Lexington Healthlexhealth.com

A leading teaching hospital in South Carolina with a network of medical centers, offering a range of services including cancer treatment and cardiovascular care

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ West Columbia 4,627 1971
6
McLeod Healthmcleodhealth.org

A leading regional healthcare system with 7 hospitals and various outpatient services, dedicated to providing top-quality medical care with a focus on continuous improvement

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Florence 4,603 1906
7
Greenville Health Systemprismahealth.org

The largest not-for-profit health organization in South Carolina, providing high-quality healthcare services to over 12 million patients annually

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenville 4,097 1912
8
Roper St. Francis Healthcarersfh.com

A leading healthcare provider in Charleston with 657 beds, over 90 facilities, and a network of 900 board-certified doctors offering primary care and subspecialties

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 4,045 1829
9
Palmetto Healthpalmettohealth.org

A leading healthcare system in the South Carolina Midlands region, providing compassionate care through six hospitals, a medical group, and training programs

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 3,200 1998
10
AnMedanmed.org

Leading not-for-profit health system in South Carolina, with focus on employee development and community collaboration to optimize patient care and staff wellness

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Anderson 2,600 1908
11
Self Regional Healthcareselfregional.org

An independent not-for-profit regional hospital providing acute, tertiary, cancer, neurosurgery, heart care, NICU, orthopedics, genetics, prevention/wellness services with employed physician network

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenwood 2,454 1951
12
Tidelands Healthtidelandshealth.org

The largest healthcare provider in the region, dedicated to promoting wellness, preventing illness, and restoring health through hospitals and outpatient locations

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Georgetown 1,358 n/a
13
Beaufort Memorial Hospitalbmhsc.org

A leading hospital with 197 licensed beds, accredited by The Joint Commission, and a dedicated medical staff providing superior healthcare services

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Beaufort 1,208 1944
14
Piedmont Medical Networkpiedmontmedicalcenter.com

Comprehensive medical center in Rock Hill, SC, offering advanced heart and stroke care, women and children's services, with a network of physician practices serving York County

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Rock Hill 1,011 1983
15
Grand Strand Medical Center โ€“ HCAmygrandstrandhealth.com

A leading healthcare facility providing advanced medical services to patients, including cardiac and neurosurgery, trauma care, and specialized treatment programs

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Myrtle Beach 974 n/a
16
Medical Services of Americamsahealthcare.com

Comprehensive provider of home healthcare services including hospice, medical equipment, diabetic supplies, respiratory services, and non-medical care, all managed by qualified professionals

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Lexington 944 1973
17
HCA Healthcare Trident Hospitalhcahealthcarecharleston.com

A top-ranking hospital in Charleston, SC, providing exceptional trauma care and part of a healthcare system with multiple facilities

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 894 1975
18
Agape Care Groupagapecaregroup.com

A regional leader in hospice and palliative care serving nearly 3,700 patients with 1,500 employees providing compassionate support and care

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Spartanburg 855 1997
19
Ob Hospitalist Groupobhg.com

Leader in providing real-time triage and hospital-based obstetric coverage to ensure consistent, timely care for pregnant patients and support for local OB/GYN physicians

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenville 763 2006
20
Your Healthyourhealth.org

Providing health services in the comfort of your own home, at physicians' offices, and through telehealth to help you feel better

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 741 n/a
21
Aiken Regional Medical Centersaikenregional.com

Aiken Regional Medical Centers in South Carolina offers comprehensive healthcare services, including emergency care, surgeries, and specialized certifications, with a focus on patient safety and quality

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Aiken 683 1917
22
eviCore healthcare formerly CareCore Nationalevicore.com

A medical benefits management company dedicated to improving healthcare outcomes by providing innovative strategies that reduce costs and promote evidence-based care

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Bluffton 622 1992
23
RALPH H. JOHNSON VA HEALTH CARE SYSTEMva.gov

A Veterans healthcare system located in Charleston, South Carolina, providing healthcare services to veterans in the United States

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 585 n/a
24
Harmony Senior Servicesharmonyseniorservices.com

Fully-integrated management services company specializing in senior housing industry, offering unique care strategies and a continuum of care for senior residents

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 578 2008
25
Medico Healthcare Services & Technologiesmedicoinc.com

Healthcare services and technology company specializing in medical billing, consulting, practice analytics, and revenue cycle management solutions for healthcare practices

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 566 1995
26
LexiCodelexicode.com

Industry-leading Health Information Management services with a team of over 1,700 credentialed professionals offering medical coding, auditing, education, and consulting solutions

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 499 1981
27
Department of Veterans Affairs, Charleston, SCvaww.visn7.med.va.gov

A VA Medical Center providing primary, secondary, and tertiary care services in South Carolina and Georgia, supporting research and medical education collaborations

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 442 n/a
28
Genesis Healthcare, Inc.genesisfqhc.org

Providing timely, affordable, compassionate primary and preventative medical care and pharmaceutical services to diverse South Carolina communities.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 412 1974
29
RSirsircm.com

A leading provider of revenue cycle management services for hospitals and physician practices, offering comprehensive outsourced solutions to optimize financial performance

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 411 1999
30
Palmetto Infusionpalmettoinfusion.com

A leading ambulatory infusion company providing unique, life-altering treatments for autoimmune diseases with a focus on restoring hope and wellness

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Pawleys Island 395 1999
31
HCA Healthcare Summerville Hospitaltridenthealthsystem.com

An acute-care hospital offering comprehensive medical services, recognized for excellence in emergency, women's and children's, cardiac, orthopedic, and stroke services in the Lowcountry community

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Summerville 383 1993
32
MUSC Health Columbia Medical Centermuschealthtogether.org

A leading healthcare provider in Columbia, SC offering top-notch medical services in a variety of specialties with a focus on quality and compassion

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 378 n/a
33
MUSC Children's Healthmusckids.org

Specializing in pediatric clinical care and research, providing comprehensive and compassionate services in over 27 specialty areas across South Carolina

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 376 n/a
34
HopeHealth, Inc.hope-health.org

Integrated health services provider with over 12 locations, offering primary care, dental care, behavioral health, pediatric care, pain management, and other healthcare services

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Florence 375 1991
35
Palmetto Primary Care Physicianspalmettoprimarycare.com

Leading multi-specialty group practice in South Carolina with over 90 providers offering primary and specialty care, innovative patient-centered approach, and state-of-the-art services

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ North Charleston 367 1996
36
Heart of Hospicelhcgroup.com

The company aims to revolutionize end-of-life care by providing high-quality hospice services to patients and their loved ones in multiple regions

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 357 2007
37
East Cooper Medical Centernovanthealth.org

A leading healthcare provider in South Carolina, offering advanced medical care, personalized treatment, and a compassionate team dedicated to patient well-being

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Mount Pleasant 347 n/a
38
MEDcare Urgent Carecarenow.com

Providing fast, friendly, and affordable healthcare services in every community with extended operating hours through the Urgent Care Group network

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 290 n/a
39
Proactive MDproactive-md.com

Innovative Advanced Primary Care company focused on helping people live healthier lives, reducing healthcare costs, and improving employee well-being

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenville 264 2016
40
Select Health of South Carolinaselecthealthofsc.com

A health insurer in South Carolina, focused on improving member health and saving on costs through coordinated care and community outreach programs

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 196 n/a
41
Charleston ENT & Allergycharlestonent.com

A leading ENT practice in South Carolina with an accredited ambulatory surgery center, offering award-winning care and opportunities for professionals to join their team

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 193 1994
42
Still Hopes Episcopal Retirement Communitystillhopes.org

A premier continuing care retirement community that fosters excellence, inspires aging adults, and offers competitive pay with generous benefits to their team members

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ West Columbia 184 n/a
43
HCA Healthcare Colleton Hospitalhcahealthcarecolleton.com

Provider of quality healthcare services for over 50 years, offering advanced technology and highly-trained physicians in a 130+ bed acute care hospital

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Walterboro 182 n/a
44
Georgia Hospice Caregeorgiahospicecare.com

Specializing in adult hospice care, we provide high-quality end-of-life services focused on love, dignity, and compassion for our patients

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Spartanburg 177 n/a
45
Presbyterian Communities of South Carolinaprescommunities.org

Non-profit organization enriching seniors' lives for over 60 years through high-quality retirement lifestyles, mission-driven service, and care across South Carolina

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 177 1958
46
Bishop Gadsden Episcopal Retirement Communitybishopgadsden.org

A leading retirement community in the Southeast with over 500 residents and 40 employees, offering a first-class lifestyle in Charleston, SC

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 177 1850
47
MedTrustridemedtrust.com

A fast-growing private EMS company providing emergent and non-emergent medical transport services, disaster response, special event coverage, and Mobile Integrated Health training programs

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Hanahan 172 2012
48
MUSC Hollings Cancer Centerhollingscancercenter.musc.edu

A leading cancer treatment center in the Southeast, offering personalized care through a team of over 60 sub-specialists

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Charleston 165 1824
49
Genesis Health Care, Incgenesisfqhc.org

A nonprofit healthcare provider in Pee Dee, SC area offering a full range of medical services to improve community health Locations in various cities

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 164 n/a
50
Elevate Eyecareelevatemyeyes.com

A network of passionate optometry practices offering comprehensive eye care services, exams, treatments, and a variety of glasses and contacts

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 162 2021
51
Coastal Carolina Hospitalnovanthealth.org

A 44-bed acute care hospital offering services such as emergency care, women's health services, and robotic-assisted surgery in Hardeeville, SC

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Hardeeville 159 2004
52
SCDHEC MIDLANDS PUBLIC HEALTH REGION

A hospital & health care company in Columbia, South Carolina focusing on public health initiatives in the Midlands region

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Columbia 153 n/a
53
MUSC Health Florence Medical Centermuschealth.org

Regional acute care facility with 396 beds, 1,500+ employees, and 250 physicians offering a wide range of healthcare services to Northeastern South Carolina residents

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Florence 151 n/a
54
MUSC Health Kershaw Medical Centermuschealthtogether.org

A healthcare system in South Carolina's Kershaw County providing a broad range of medical and wellness services to improve residents' health and well-being

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Camden 149 n/a
55
MedBridge Healthcare LLCmedbridgehealthcare.com

A leading provider of sleep laboratory management services, partnering with hospitals and physician practices to offer comprehensive care for patients with sleep disorders

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenville 148 n/a
56
Always Best Care Senior Services Greenvillealwaysbestcare.com

This company provides compassionate home care and transportation services for seniors, as well as assistance in selecting the best assisted living community

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Greenville 82 2010

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

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