| # | Company | Employees |
|---|---|---|
| 1 | 80,633 | |
| 2 |
Duke Universityduke.edu
Private research university offering undergraduate, graduate, and professional education with strong emphasis on research and academic excellence. |
16,307 |
| 3 |
Duke University Health Systemdukehealth.org
Academic health system focused on innovative research, education, evidence-based medicine, community health improvement, and eliminating health disparities globally and locally. |
12,096 |
| 4 |
FHI 360fhi360.org
Nonprofit organization advancing equity, health, and well-being worldwide through research, resources, and locally led, data-driven solutions. |
8,644 |
| 5 |
University of New Hampshireunh.edu
Public research university offering undergraduate and graduate programs, engaging in teaching, research, creative expression, and community service. |
6,952 |
| 6 |
Blue Cross NCbluecrossnc.com
Leading provider of health insurance in North Carolina with a focus on improving health and well-being through innovative approaches and passionate employees |
6,148 |
| 7 |
Avalaraavalara.com
Provides an agentic AI platform for global tax and compliance, automating calculations, return filings, and exemption certificate management for businesses worldwide. |
5,649 |
| 8 |
Durham Public Schoolsdpsnc.net
A public school district in Durham, North Carolina providing outstanding education to students, helping them reach their full potential and succeed in college and the workforce |
4,416 |
| 9 |
Duke University Hospital
A leading academic medical center known for exceptional care, groundbreaking research, and commitment to improving the health of individuals and communities |
3,704 |
| 10 |
Association of International Certified Professional Accountantsaicpa-cima.com
Empowering highly skilled accountants with knowledge and insight to meet today's demands and drive a dynamic profession worldwide |
3,178 |
| 11 |
North Carolina Central Universitynccu.edu
A historic institution offering diverse bachelor's, master's, law, and PhD programs that prepare students to become global leaders and engaged problem solvers |
3,102 |
| 12 |
Duke University School of Medicinemedschool.duke.edu
Leading medical school with a focus on interdisciplinary collaboration, research, and innovation to improve human health locally and globally |
2,542 |
| 13 |
Toshiba Global Commerce Solutionscommerce.toshiba.com
Global leader in retail store technology, providing integrated in-store solutions that enhance customer engagement, transform the in-store experience, and accelerate digital transformation |
2,537 |
| 14 |
Self-Help Credit Unionself-help.org
A family of nonprofit organizations providing fair lending, community development, research, and policy support to create ownership and economic opportunity for all |
2,523 |
| 15 |
Wolfspeedwolfspeed.com
Global leader in Silicon Carbide technology for over 30 years, enabling breakthroughs in electric vehicles, 5G, renewable energy, aerospace, and defense industries |
2,460 |
| 16 |
Rewriting the Coderewritingthecode.org
Global community supporting women in technology with education, mentorship, scholarships, resources, and events for career readiness. |
2,399 |
| 17 |
City of Durhamdurhamnc.gov
Local government providing employment with competitive benefits, career growth, and a supportive workplace in a vibrant community. |
1,816 |
| 18 |
KBI Biopharmakbibiopharma.com
Provides fully-integrated, accelerated drug development and biomanufacturing services to pharmaceutical and biotechnology companies globally with world-class analytical capabilities. |
1,694 |
| 19 |
Creewolfspeed.com
Specializing in Silicon Carbide technology, we provide cutting-edge solutions and innovations Follow us at Wolfspeed, Inc for the latest updates |
1,658 |
| 20 |
Alliance Healthalliancehealthplan.org
This company manages public mental health, intellectual/developmental disability, and substance abuse services for Medicaid-eligible citizens in multiple counties, focusing on whole-person care and community-based support |
1,607 |
| 21 |
JAGGAERjaggaer.com
It provides enterprise procurement and supplier collaboration solutions, enhancing decision-making and automating processes for organizations globally, with proven expertise. |
1,474 |
| 22 |
Durham County Governmentdconc.gov
Provides local government services, elects commissioners, manages county operations through a professional manager, supports community living and business environment. |
1,296 |
| 23 |
Work At Home Jobsworkathomejobs.org
This company helps people find legitimate work from home jobs by aggregating over 40,000 opportunities each month from various sources |
1,276 |
| 24 |
Measurement Incorporatedmeasurementinc.com
A leading provider of customized educational assessment services, offering performance assessment scoring, test development, and school improvement services nationwide |
1,193 |
| 25 |
Q虏 Solutionslabs.iqvia.com
Company undergoing rebranding and transition from Q虏 Solutions to IQVIA Laboratories, directing audience to new website and LinkedIn. |
1,181 |
| 26 |
Bioventusbioventus.com
Develops innovations for active healing, providing products in pain treatment, restorative therapies, and surgical solutions for patients worldwide since 2012. |
1,153 |
| 27 |
International Society of Automation (ISA)isa.org
Non-profit organization dedicated to advancing automation by providing global standards, certifications, education, training, and networking opportunities for professionals worldwide. |
1,152 |
| 28 |
AICPAaicpa-cima.com
Empowering highly skilled accountants with knowledge and foresight to meet challenges, drive a dynamic profession, build trust, create opportunities, and grow prosperity worldwide |
1,132 |
| 29 |
Bell and Howellbellhowell.net
Provides automation services and solutions maximizing operational efficiency and customer experiences across diverse markets like print, retail, pharma, and manufacturing. |
1,091 |
| 30 |
Velocity Clinical Research, Inc.velocityclinical.com
Dedicated clinical research sites deliver high-quality trial data from many patients as quickly as possible, ensuring exemplary patient care throughout the process. |
1,036 |
| 31 |
Durham Technical Community Collegedurhamtech.edu
Provider of high-quality, affordable technical and career education with articulation agreements for bachelor's degrees, plus continuing education and adult literacy programs |
1,033 |
| 32 |
Duke Clinical Research Institutedcri.org
A global leader in clinical research, conducting groundbreaking trials, managing patient registries, and publishing impactful research to improve healthcare quality |
1,009 |
| 33 |
Duke University - The Fuqua School of Businessfuqua.duke.edu
A prestigious business school in Durham, NC, known for its renowned faculty, research centers, and collaborative culture, ranking among top US business schools |
995 |
| 34 |
BioAgilytixbioagilytix.com
Global CRO specializing in PK, immunogenicity, biomarkers, and cell-based assays for drug development, with locations across the US, Australia, and Germany |
923 |
| 35 |
Beta Alpha Psi International (BAP)linktr.ee
Founded in 1919, this organization supports excellence in financial and business information education through networking, professional development, and ethical responsibility |
917 |
| 36 |
Duke Regional Hospitaldukehealth.org
A leading healthcare facility providing comprehensive inpatient, outpatient, surgical, emergency care, and specialized services to the community with high-quality, safe care |
900 |
| 37 |
FastMed Urgent Carefastmed.com
A leading urgent care provider offering acute/episodic, preventive, and occupational healthcare, as well as family medicine at selected clinics and telemedicine services |
870 |
| 38 |
PowerSecure, Inc.powersecure.com
Innovative provider of energy solutions, specializing in distributed energy resources, microgrid solutions, and energy efficient lighting technology for utilities and customers |
861 |
| 39 |
Automatic Data Processingadp.com
Global provider of cloud-based HCM solutions including HR, payroll, talent, and benefits administration Specializes in decision support technology customization for companies |
793 |
| 40 |
Rhorhoworld.com
A global CRO focused on guiding clients through program strategies, clinical trial challenges, and high-quality marketing applications with expertise and collaboration |
792 |
| 41 |
Teamworksteamworks.com
Specialized platform for high performance management, recruitment, branding, and community building for sports, military, and public safety organizations worldwide |
785 |
| 42 |
Mestessamestessa.com
A company offering customizable handbags and accessories, allowing customers to express their personal style with interchangeable modules for continued customization |
722 |
| 43 |
MDCmdcinc.org
Nonprofit organization based in Durham, NC since 1967, working to improve economic mobility and advance equity in the Southern region |
650 |
| 44 |
Duke University Pratt School of Engineeringpratt.duke.edu
A top-ranked engineering school providing rigorous education, research, and societal impact to cultivate purposeful and impactful lives for students |
638 |
| 45 |
SMT (SportsMEDIA Technology)smt.com
Provider of advanced technology and services for sports broadcasts, events, and entertainment, offering a wide range of innovative solutions to enhance productions |
636 |
| 46 |
Strata Clean Energystratacleanenergy.com
A vertically integrated renewable energy company based in North Carolina, specializing in solar and storage development, construction, O&M, and Asset Management |
634 |
| 47 |
BioCryst Pharmaceuticals, Inc.biocryst.com
Development of oral small-molecule and protein therapeutics targeting hereditary angioedema and other rare, difficult-to-treat diseases worldwide. |
613 |
| 48 |
Chilternfortrea.com
A company specializing in tailored clinical trial solutions for biotech ventures, offering expanded services and a personalized experience for clients |
585 |
| 49 |
LabConnectlabconnect.com
LabConnect accelerates drug development by offering tailored, comprehensive central laboratory services and scientific support to pharma, biotech companies, and CROs globally |
585 |
| 50 |
SRC Research Scholars Programsrc.org
The company provides educational opportunities for students and researchers in the semiconductor industry, fostering industry-relevant research and talent development |
511 |
| 51 |
AISIN North Carolina Corporationaisinnc.com
A leading manufacturer of automatic transmissions and components, creating products with a focus on quality and a strong team environment |
500 |
| 52 |
Durham VA Health Care Systemva.gov
Providing healthcare services to veterans in central and eastern North Carolina since 1953, improving the health of those who served our nation |
496 |
| 53 |
Duke Health
A medical practice company located in Durham, North Carolina, providing health services and care to patients in the United States |
476 |
| 54 |
Implusimplus.com
Industry leader in active lifestyle accessories, providing innovative products to retail outlets in 60 countries worldwide Headquarters in Durham, North Carolina |
473 |
| 55 |
Strawbridge Studios, Inc.strawbridge.net
A full-service organization for school photography, providing portraits, yearbooks, administrative software, certificates, banners, and more to make "Picture Day" a success |
464 |
| 56 |
North Carolina School of Science and Mathematicsncssm.edu
A public residential high school in North Carolina focused on STEM education, providing challenging programs for talented students through various platforms |
462 |
| 57 |
Duke University School of Nursingnursing.duke.edu
Educating future nursing leaders, advancing nursing science globally, and offering a range of nursing degrees to college graduates |
453 |
| 58 |
Cypress Creek Energyccrenew.com
A leading solar company in the US, Cypress Creek Renewables develops, builds, and operates solar facilities to create a safer, cleaner world |
444 |
| 59 |
LCIlcindustries.com
A provider of manufacturing, distribution, wholesale, retail, and technology consulting solutions, with a focus on employing Americans who are blind or visually impaired |
436 |
| 60 |
Avance Careavancecare.com
Innovative primary care provider in North Carolina since 2008, offering convenient, cost-effective health care services with industry-leading patient satisfaction and efficiency |
433 |
| 61 |
Goss Internationalgossinternational.com
Supplier of automated web offset presses for various printing applications, headquartered in Durham, NH with manufacturing centers in North America, Asia, and Europe |
432 |
| 62 |
Parata Systemsparata.com
Empowering pharmacies with technology solutions to enhance patient care by automating tasks, improving medication adherence, and streamlining workflows |
421 |
| 63 |
BCLbcltraining.com
A Durham-based agency specializing in developing effective learning programs tailored to address clients' specific performance needs Founded in 2013 |
421 |
| 64 |
Clarkston Consultingclarkstonconsulting.com
Providing strategy, operations, implementation, and managed services with data-driven approach for life sciences, consumer products, and retail companies. |
421 |
| 65 |
IIS First
Specializes in developing tailor-made software solutions for municipal governments at the city and county levels to enhance operational efficiency and citizen services |
403 |
| 66 |
Duke University School of Lawlaw.duke.edu
A forward-thinking law school that prepares students for the legal profession, leads in legal improvement, and fosters creativity and innovation |
399 |
| 67 |
Duke Health Integrated Practicedukehealth.org
A leading academic multi-specialty physician practice in the United States, offering high-quality primary and specialty care, research, and medical training |
394 |
| 68 |
Duke Cancer Institutedukecancerinstitute.org
A collaborative and innovative cancer institute at a renowned university and medical center, creating breakthroughs and transforming possibilities in cancer care |
374 |
| 69 |
The Chronicledukechronicle.com
A student-run newspaper at Duke University, founded in 1905, covering campus news and managed by students with professional staff for business operations |
374 |
| 70 |
Burt's Beesburtsbees.com
Leading natural skincare brand offering consciously-crafted products with powerful, nutrient-rich ingredients to nourish and balance skin, with a focus on sustainability and employee well-being |
370 |
| 71 |
McKinneymckinney.com
Creative, media, and influencer agency with multiple national offices, recognized for exceptional workplace culture and award-winning work for top brands |
369 |
| 72 |
Duke Corporate Educationdukece.com
Duke CE helps leaders navigate uncertainty by providing custom leadership programs ranked highly by the Financial Times and Business Week |
355 |
| 73 |
Perconapercona.com
Specializing in open source databases, we scale, secure, and manage operations on popular platforms for global brands across industries |
348 |
| 74 |
Revco Solutionsrevcosolutions.com
Healthcare revenue cycle experts offering patient communications and intelligence tools, assisting with access, denials, collections, and compliance for optimal patient experience |
320 |
| 75 |
Duke University Sanford School of Public Policysanford.duke.edu
An intellectual community at Duke University focused on innovative ideas in public policy, offering various degree programs and engaging podcasts |
314 |
| 76 |
Bring ITbringitps.com
Global team of Cloud ERP experts delivering business transformation and technology solutions for companies worldwide Named on Inc 5000 list three years in a row |
313 |
| 77 |
Carolina Outreach, LLCcarolinaoutreach.com
Provider of high-quality behavioral health services emphasizing person-centered care and client-driven approach to help individuals and families achieve positive outcomes |
309 |
| 78 |
MedPharmmedpharm.com
Supports companies navigating the complexity of topical and transdermal drug development and manufacturing, from formulation and preclinical research to clinical trial supply and commercial manufacturing. |
285 |
| 79 |
The Summit Churchsummitchurch.com
A multi-location church in the Triangle region with a vision to "Love God, Love Each Other, and Love Our World" Visit wwwsummitrducom for more information |
278 |
| 80 |
Dollar Shave Clubdollarshaveclub.com
Subscription-based service offering affordable razors and personal care products, expanding into grooming essentials with a humorous, value-driven approach. |
261 |
| 81 |
Solysticsolystic.com
Provides end-to-end automation solutions for mail, express, parcels, e-commerce, and retail industries, focusing on sorting, distribution, and intralogistics processes. |
258 |
| 82 |
Duke Athleticsgoduke.com
This company's mission embodies Duke University's values of engaging the mind, elevating the spirit, and inspiring excellence within its athletics program |
229 |
| 83 |
Crediblecredible.com
Operates an online marketplace for comparing personalized prequalified rates and quotes from lenders and carriers for loans and insurance, simplifying the financial product search. |
225 |
| 84 |
Silly Propertiesbetterpropertiesllc.com
A vertically integrated real estate firm specializing in value-add residential and build-to-rent investments, focused on providing upgraded properties and superior service in North Carolina cities |
216 |
| 85 |
Spoonflowerspoonflower.com
An e-commerce platform for unique fabrics, wallpaper, and home decor allowing individuals to create, sell, and shop colorful and patterned products internationally |
202 |
| 86 |
TeraRecon, Inc.terarecon.com
A global provider of AI-empowered solutions for radiology, oncology, cardiology, neurology, and vascular surgery, improving clinical workflows and delivering actionable insights |
197 |
| 87 |
CMG Consultingcmgconsulting.com
A strategic consulting firm partnering with enterprise organizations to drive transformation, growth, and success through inventive strategies and collaborative execution |
186 |
| 88 |
The Duke Human Vaccine Institutedhvi.duke.edu
A leader in infectious disease research, DHVI focuses on developing vaccines, diagnostics, and therapeutics to address global health challenges and disparities |
184 |
| 89 |
PBS North Carolinapbsnc.org
Providing quality content and services to engage communities, enhance education, enrich lives, and share the stories of North Carolina |
184 |
| 90 |
UNH Onlinecps.unh.edu
A public research university offering high-quality undergraduate and graduate programs, focused on education through collaboration in teaching, research, and more |
183 |
| 91 |
Durham Bulls Baseball Clubmilb.com
A historic Minor League Baseball team providing affordable family entertainment, strong baseball, community programs, and special events in the Triangle area |
181 |
| 92 |
enieniweb.com
An industry-leading provider of Total Wellbeing Solutions for employee benefits, focused on enhancing the employee experience and maximizing ROI |
177 |
| 93 |
Duke HomeCare & Hospicedukehealth.org
Provider of home health care, infusion therapy, hospice care, and bereavement services, offering comprehensive and individualized support for patients with various medical conditions |
176 |
| 94 |
Croasdaile Village Retirement Communitycroasdailevillage.org
A retirement community in Durham offering a serene rural setting with city conveniences and a focus on personalized care and amenities |
176 |
| 95 |
The Link Grouptlg.com
Providing innovative global market research services with a focus on healthcare but expertise in consumer products, technology, retail, and more |
174 |
| 96 |
Project BUILDstudentaffairs.duke.edu
A Duke University pre-orientation program focusing on community service in Durham area, connecting upperclassmen leaders with first-year participants |
173 |
| 97 | 172 | |
| 98 |
Durham Police Departmentdurhamnc.gov
Protecting Durham residents' lives and property through law enforcement and safety education |
172 |
| 99 |
The Forest at Dukeforestduke.org
A vibrant retirement community providing care and independence to residents, offering a variety of amenities and activities for a fulfilling lifestyle |
172 |
| 100 |
Upswingupswing.io
Upswing offers a platform to support non-traditional learners through online tutoring, engagement optimization, and data-driven at-risk student identification and support |
168 |
Turn this list into pipeline
Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.
How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.
The same list elsewhere in United States
- The largest companies in the United States 91,669
- The largest companies in California 12,813
- The largest companies in New York State 10,485
- The largest companies in Texas 8,086
- The largest companies in Florida 4,945
- The largest companies in Illinois 4,175
- The largest companies in Pennsylvania 3,110
- The largest companies in Massachusetts 3,093
- The largest companies in Georgia 2,632
- The largest companies in Ohio 2,618
- The largest companies in New Jersey 2,569
- The largest companies in Virginia 2,503
- The largest companies in Michigan 2,346
- The largest companies in North Carolina 2,174
- The largest companies in Alabama 1,806
- The largest companies in Washington State 1,785
- The largest companies in Colorado 1,774
- The largest companies in Minnesota 1,700
- The largest companies in Maryland 1,527
- The largest companies in Wisconsin 1,482
- The largest companies in New York 6,920
- The largest companies in San Francisco 2,030
- The largest companies in Houston 1,791
- The largest companies in Chicago 1,668