The companies in Durham span a range of sectors, with a notable concentration in healthcare, biotechnology, and software development. These are primarily large organizations, including established universities and global research firms. IQVIA provides clinical research and healthcare intelligence, while Duke University is a private research institution. FHI 360 focuses on international trade and development, and Avalara offers an AI platform for global tax and compliance.
A clear pattern among these companies is the strong presence of the life sciences and technology sectors. Companies like KBI Biopharma, specializing in drug development and biomanufacturing, and Wolfspeed, a leader in Silicon Carbide technology, highlight Durham's role as a hub for advanced research and technological innovation. Additionally, several companies, including Cree and Q² Solutions, are engaged in semiconductor manufacturing and pharmaceutical research, respectively.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 | 80,633 | ||||
| 2 |
Duke Universityduke.edu
Private research university offering undergraduate, graduate, and professional education with strong emphasis on research and academic excellence. |
16,307 | |||
| 3 |
FHI 360fhi360.org
Nonprofit organization advancing equity, health, and well-being worldwide through research, resources, and locally led, data-driven solutions. |
8,644 | |||
| 4 |
Avalaraavalara.com
Provides an agentic AI platform for global tax and compliance, automating calculations, return filings, and exemption certificate management for businesses worldwide. |
5,649 | |||
| 5 |
Toshiba Global Commerce Solutionscommerce.toshiba.com
Global leader in retail store technology, providing integrated in-store solutions that enhance customer engagement, transform the in-store experience, and accelerate digital transformation |
2,537 | |||
| 6 |
Wolfspeedwolfspeed.com
Global leader in Silicon Carbide technology for over 30 years, enabling breakthroughs in electric vehicles, 5G, renewable energy, aerospace, and defense industries |
2,460 | |||
| 7 |
KBI Biopharmakbibiopharma.com
Provides fully-integrated, accelerated drug development and biomanufacturing services to pharmaceutical and biotechnology companies globally with world-class analytical capabilities. |
1,694 | |||
| 8 |
Creewolfspeed.com
Specializing in Silicon Carbide technology, we provide cutting-edge solutions and innovations Follow us at Wolfspeed, Inc for the latest updates |
1,658 | |||
| 9 |
JAGGAERjaggaer.com
It provides enterprise procurement and supplier collaboration solutions, enhancing decision-making and automating processes for organizations globally, with proven expertise. |
1,474 | |||
| 10 |
Q² Solutionslabs.iqvia.com
Company undergoing rebranding and transition from Q² Solutions to IQVIA Laboratories, directing audience to new website and LinkedIn. |
1,181 | |||
| 11 |
Bioventusbioventus.com
Develops innovations for active healing, providing products in pain treatment, restorative therapies, and surgical solutions for patients worldwide since 2012. |
1,153 | |||
| 12 |
AICPAaicpa-cima.com
Empowering highly skilled accountants with knowledge and foresight to meet challenges, drive a dynamic profession, build trust, create opportunities, and grow prosperity worldwide |
1,132 | |||
| 13 |
Velocity Clinical Research, Inc.velocityclinical.com
Dedicated clinical research sites deliver high-quality trial data from many patients as quickly as possible, ensuring exemplary patient care throughout the process. |
1,036 | |||
| 14 |
Duke University - The Fuqua School of Businessfuqua.duke.edu
A prestigious business school in Durham, NC, known for its renowned faculty, research centers, and collaborative culture, ranking among top US business schools |
995 | |||
| 15 |
BioAgilytixbioagilytix.com
Global CRO specializing in PK, immunogenicity, biomarkers, and cell-based assays for drug development, with locations across the US, Australia, and Germany |
923 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
Automatic Data Processingadp.com
Global provider of cloud-based HCM solutions including HR, payroll, talent, and benefits administration Specializes in decision support technology customization for companies |
793 | |||
| 17 |
Rhorhoworld.com
A global CRO focused on guiding clients through program strategies, clinical trial challenges, and high-quality marketing applications with expertise and collaboration |
792 | |||
| 18 |
SMT (SportsMEDIA Technology)smt.com
Provider of advanced technology and services for sports broadcasts, events, and entertainment, offering a wide range of innovative solutions to enhance productions |
636 | |||
| 19 |
BioCryst Pharmaceuticals, Inc.biocryst.com
Development of oral small-molecule and protein therapeutics targeting hereditary angioedema and other rare, difficult-to-treat diseases worldwide. |
613 | |||
| 20 |
Chilternfortrea.com
A company specializing in tailored clinical trial solutions for biotech ventures, offering expanded services and a personalized experience for clients |
585 | |||
| 21 |
LabConnectlabconnect.com
LabConnect accelerates drug development by offering tailored, comprehensive central laboratory services and scientific support to pharma, biotech companies, and CROs globally |
585 | |||
| 22 |
AISIN North Carolina Corporationaisinnc.com
A leading manufacturer of automatic transmissions and components, creating products with a focus on quality and a strong team environment |
500 | |||
| 23 |
Implusimplus.com
Industry leader in active lifestyle accessories, providing innovative products to retail outlets in 60 countries worldwide Headquarters in Durham, North Carolina |
473 | |||
| 24 |
Goss Internationalgossinternational.com
Supplier of automated web offset presses for various printing applications, headquartered in Durham, NH with manufacturing centers in North America, Asia, and Europe |
432 | |||
| 25 |
Duke University School of Lawlaw.duke.edu
A forward-thinking law school that prepares students for the legal profession, leads in legal improvement, and fosters creativity and innovation |
399 | |||
| 26 |
Duke Corporate Educationdukece.com
Duke CE helps leaders navigate uncertainty by providing custom leadership programs ranked highly by the Financial Times and Business Week |
355 | |||
| 27 |
Perconapercona.com
Specializing in open source databases, we scale, secure, and manage operations on popular platforms for global brands across industries |
348 | |||
| 28 |
Bring ITbringitps.com
Global team of Cloud ERP experts delivering business transformation and technology solutions for companies worldwide Named on Inc 5000 list three years in a row |
313 | |||
| 29 |
MedPharmmedpharm.com
Supports companies navigating the complexity of topical and transdermal drug development and manufacturing, from formulation and preclinical research to clinical trial supply and commercial manufacturing. |
285 | |||
| 30 |
Solysticsolystic.com
Provides end-to-end automation solutions for mail, express, parcels, e-commerce, and retail industries, focusing on sorting, distribution, and intralogistics processes. |
258 | |||
Turn this list into pipeline
Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.
How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Durham
The same list elsewhere in United States
- Multinational companies in the United States 16,197
- Multinational companies in California 2,592
- Multinational companies in New York State 2,216
- Multinational companies in Texas 1,418
- Multinational companies in Florida 897
- Multinational companies in Illinois 831
- Multinational companies in Massachusetts 637
- Multinational companies in New Jersey 624
- Multinational companies in Georgia 521
- Multinational companies in Pennsylvania 472
- Multinational companies in Michigan 468
- Multinational companies in Alabama 416
- Multinational companies in Virginia 396
- Multinational companies in Ohio 390
- Multinational companies in North Carolina 358
- Multinational companies in Washington State 288
- Multinational companies in Colorado 228
- Multinational companies in New York 1,836
- Multinational companies in San Francisco 446
- Multinational companies in Houston 402
- Multinational companies in Chicago 366
- Multinational companies in Miami 289
- Multinational companies in Atlanta 252
- Multinational companies in Boston 241