This selection of manufacturers in Prague includes large, established companies across diverse sectors. Zentiva, founded in 1488, is a pan-European pharmaceutical company. ORLEN Unipetrol, established in 1994, is a refinery and petrochemical group. Plzeňský Prazdroj produces beer, and Mattoni 1873 specializes in bottled mineral water. ComAp Group, founded in 1991, provides smart power control solutions, while Prusa Research, established in 2012, manufactures 3D printers.BTL Medical & Healthcare Technologies, founded in 1993, focuses on cardiology, physical therapy, and medical aesthetics. NIK produces energy metering devices.PRO.MED.CS, founded in 1989, specializes in drugs for gastrointestinal, cardiovascular, and musculoskeletal areas.Orkla Foods Česko a Slovensko focuses on branded consumer goods.MTX Group a.s. is an industrial, commercial, and manufacturing holding company.Bosch Česká republika is known for innovative technologies.Draslovka, founded in 1906, is a family company in the CN-based specialty chemical industry.Pivovary Staropramen s.r.o., founded in 1869, produces beer.2N, founded in 1991, specializes in custom IP intercoms, access control, and communication solutions. The companies in this list show a strong presence in food and beverage manufacturing, pharmaceuticals, and industrial technology. Many of these firms have a long history, with several founded in the late 19th or early 20th century, indicating a mature industrial base in the city. There is also a notable cluster of companies founded around the early 1990s, suggesting a period of significant industrial development.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Zentivazentiva.com
A Pan-European pharmaceutical company developing, manufacturing, and providing affordable medicines in key therapeutic areas with a focus on growth and supply security |
3,665 | |||
| 2 |
ORLEN Unipetrolorlenunipetrol.cz
A leading refinery and petrochemical group in the Czech Republic and Central/Eastern Europe, with a focus on downstream production and retail fuel distribution |
1,182 | |||
| 3 |
Plzeňský Prazdrojprazdroj.cz
Leading Czech beer producer with four breweries exporting to over 50 countries, promoting responsible alcohol consumption through the Responsible Brewers Initiative |
809 | |||
| 4 | 783 | ||||
| 5 |
ComAp Groupcomap-control.com
Provider of smart power control solutions and services for independent and backup power generation markets, with a focus on flexibility, scalability, and sustainability |
633 | |||
| 6 |
BTL Medical & Healthcare Technologiesbtl-kariera.cz
Company brings disruptive technologies to healthcare, focusing on cardiology, physical therapy, and medical aesthetics. Develops and produces devices from idea to serial production, distributing globally. |
630 | |||
| 7 |
NIKnik-global.com
A leading manufacturer in Eastern Europe producing energy metering devices, automatic meter reading systems, electrical equipment, and providing substation design and modernization services |
527 | |||
| 8 |
PRO.MED.CSpromedcs.com
A leading Czech pharmaceutical company specializing in developing and producing tablets, capsules, and drugs for gastrointestinal, cardiovascular, and musculoskeletal areas Exporting to over 30 countries |
516 | |||
| 9 |
Orkla Foods Česko a Slovenskoorkla.jobs.cz
We are part of a multinational company focused on branded consumer goods in Central Europe, producing a variety of food products |
501 | |||
| 10 |
Mattoni 1873mattoni1873.cz
A leading producer of bottled mineral and spring water in Central Europe, focusing on quality, innovation, and market leadership for over 140 years |
490 | |||
| 11 |
MTX Group a.s.mtxgroup.cz
MTX Group is a significant industrial, commercial, and manufacturing holding company in the Czech Republic, focusing on managing, financing, and coordinating its subsidiaries |
490 | |||
| 12 |
Prusa Researchprusa3d.com
A leading manufacturer of 3D printers based in Prague, providing innovative solutions for businesses and individuals worldwide with a focus on growth and quality |
489 | |||
| 13 |
Bosch Česká republikabosch.cz
A global company known for innovative technologies and groundbreaking inventions in automotive, tools, and more, with over 8000 employees in the Czech Republic |
468 | |||
| 14 |
Draslovkadraslovka.com
A Czech family company with a strong market position in the CN-based specialty chemical industry, focused on sustainable products and solutions |
341 | |||
| 15 |
Pivovary Staropramen s.r.o.pivovary-staropramen.cz
A leading producer of beer in Czech Republic, exporting to 35 countries, with a focus on innovation, sustainability, quality, and local communities |
327 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
STADA Czech Republicstada-pharma.cz
A leading manufacturer of high-quality medications and dietary supplements, with a focus on health, well-being, and improving quality of life globally |
322 | |||
| 17 |
PBS GROUP a.s.pbs.cz
A global engineering company group specializing in aerospace, power engineering, investment casting, and cryogenics, with a focus on innovation and quality |
320 | |||
| 18 | 275 | ||||
| 19 | 262 | ||||
| 20 |
ALPINE PRO, a.s.alpinepro.cz
A leading Czech outdoor apparel and accessories company with a strong presence in domestic and international markets, known for quality designs and collaborations with professional athletes |
108 | |||
| 21 | 83 | ||||
| 22 |
ATG (Advanced Technology Group)en.atg.cz
Provider of complete solutions for NDT, offering products and services for industrial inspections, personnel qualification, and establishment of NDT processes |
74 | |||
| 23 |
UJP PRAHA a.s.ujp.cz
The company specializes in uranium processing, production of transport/storage containers for ionizing radiation, and manufacturing shielding materials for various industries |
54 | |||
| 24 |
Seco Industries, s.r.o.secoindustries.cz
A leading foundry in the Czech Republic specializing in precision castings for European automotive, tractor, and construction machinery manufacturers Also produces diesel engine cylinders |
43 | |||
| 25 |
MINIB, a.s.minib.cz
European manufacturer of convectors and chilled beams for heating, cooling, and ventilation Specializes in eco-friendly solutions for non-typical customer requirements |
34 | |||
| 26 |
ADVACAM Camerasadvacam.com
Leader in photon-counting imaging technology, designing cameras for diverse applications from space to medicine, revolutionizing industries with cutting-edge CERN-based technology |
30 | |||
| 27 |
4M Systems a.s.4mtactical.com
Manufacturer of tactical gear for Military and Law Enforcement sectors, offering innovative solutions based on extensive experience and collaboration with CZUB |
15 | |||
| 28 |
OlifeEnergyolife-energy.com
A Czech tech company specializing in developing and manufacturing AC/DC charging stations for electric vehicles |
11 | |||
| 29 |
Stabilplastikstabilplastik.cz
Specializing in producing and selling plastic shipping pallets and recycled plastic products since 1999 |
6 | |||
| 30 |
STRATOSYSTstratosyst.com
Develops solar-powered High Altitude Pseudo-Satellites (HAPS) for Earth observation, telecommunications, and defense, making satellite technology affordable and environmentally friendly. |
5 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
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- Corporate groups and holding companies in Prague 33
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- SaaS companies in Prague 29
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