These large multinational companies in Prague operate across diverse sectors. Key players include ČEZ, a major energy group in Central and Southeastern Europe, and Zentiva, a Pan-European pharmaceutical company. The list also features UniCredit Bank CZ & SK, a leading financial institution, and Unicorn, a European IT services provider. Other significant companies are T-Mobile Czech Republic, providing mobile communication services, and the Czech Technical University in Prague, a leading technical education institution.
A notable pattern among these companies is their strong presence in the financial services, telecommunications, and higher education sectors. Many of these firms also have a pan-European or regional operational scope, indicating Prague's role as a hub for international business and academic institutions.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 | 5,944 | ||||
| 2 |
Zentivazentiva.com
A Pan-European pharmaceutical company developing, manufacturing, and providing affordable medicines in key therapeutic areas with a focus on growth and supply security |
3,665 | |||
| 3 |
UniCredit Bank CZ & SKunicreditbank.cz
Leading financial institution providing corporate finance, commercial real estate funding, and private banking services to individual and corporate clients across Czech and Slovak markets. |
2,123 | |||
| 4 |
Unicornunicorn.com
A European IT company providing high value solutions for various industries, offering internet services for small businesses and promoting online education |
2,105 | |||
| 5 |
T-Mobile Czech Republic a.s.t-mobile.cz
Providing reliable and accessible mobile communication services with a human approach, focusing on quality, teamwork, and social responsibility. |
2,016 | |||
| 6 |
Czech Technical University in Praguecvut.cz
Leading Central European technical institution providing engineering, architecture, and business education through eight faculties, specialized research laboratories, and diverse degree programs for students. |
1,948 | |||
| 7 |
Charles Universitycuni.cz
A prestigious university in Prague, founded in 1348, offering a wide range of academic programs with a strong focus on Natural Sciences |
1,798 | |||
| 8 |
People in Needclovekvtisni.cz
A non-profit organization focused on humanitarian aid, poverty relief, human rights advocacy, and education in 42 countries worldwide |
1,785 | |||
| 9 |
Kaufland Česká republika v.o.s.kaufland.cz
A successful international business operating 140 stores and 2 distribution centers in the Czech Republic, with a focus on employee satisfaction and recognition |
1,718 | |||
| 10 |
České dráhy, a.s.ceskedrahy.cz
The largest railway carrier in the Czech Republic, providing passenger and freight services with 21,000 employees and a focus on modernizing the country's railway system |
1,585 | |||
| 11 | 1,438 | ||||
| 12 |
FF Groupff-group.ai
An innovative data solution provider specializing in Edge and data solutions for road traffic and parking vendors, offering AI intelligence platform for informed decisions |
1,386 | |||
| 13 |
EUROWAGeurowag.com
Eurowag is a pan-European payments & mobility platform for commercial road transportation, providing innovative solutions for drivers and operators |
1,349 | |||
| 14 |
OVB Allfinanz a.s.ovb.cz
A leading financial advisory company in Europe since 1970, providing comprehensive services to over 28 million private and corporate clients in 14 countries |
1,340 | |||
| 15 |
ORLEN Unipetrolorlenunipetrol.cz
A leading refinery and petrochemical group in the Czech Republic and Central/Eastern Europe, with a focus on downstream production and retail fuel distribution |
1,182 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
Metrostav a.s.metrostav.cz
A leading construction firm in the Czech Republic, part of a group working on projects domestically and internationally, with a strong reputation and significant revenues |
1,154 | |||
| 17 |
Czech University of Life Sciences Pragueczu.cz
A top Prague university with over 21,000 students focusing on economics, management, ecology, technology, agriculture, forestry, and natural sciences |
1,095 | |||
| 18 |
IBA Groupibagroupit.com
A leading IT service provider in Eastern Europe offering software development, migration, maintenance, support, and consulting services with a global presence |
1,070 | |||
| 19 |
PwC Czech Republicpwc.com
A global network of firms providing assurance, advisory, and tax services, committed to delivering quality solutions to multinational and domestic clients |
1,015 | |||
| 20 |
MSD Czech Republicmsd.cz
This company in Czech Republic showcases exciting events, meet-ups, and people within their organization through a closer look |
1,014 | |||
| 21 |
University of Chemistry and Technology in Prague (UCT Prague)vscht.cz
Leading educational institution in Central Europe with almost 200 years of tradition, offering advanced technologies, international student exchanges, and prestigious career opportunities |
924 | |||
| 22 |
Traskthetrask.com
Providing tailored technology and business consulting services including BPM, data science, integration, security, and mobile solutions for diverse industries. |
916 | |||
| 23 |
SPORTISIMOsportisimo.cz
An international sporting goods retailer with 220+ stores in the EU, 4,000+ employees, a fast-growing e-commerce operation, and over 10 million items in stock |
899 | |||
| 24 |
KPMG Czech Republickpmg.com
The company provides audit, tax, advisory, and legal services as part of a global network with over 219,000 experts in 147 countries |
892 | |||
| 25 |
AAA AUTOaaaauto.cz
AURES Holdings offers a wide range of mobility solutions, including automotive retail systems and a variety of car brands, with a focus on career development and stability for employees |
824 | |||
| 26 |
Deloitte Czech Republicdeloitte.cz
A global network of firms providing audit, consulting, financial advisory, risk management, and tax services to clients worldwide Leading professional services in Czech Republic |
822 | |||
| 27 |
Ministry of Foreign Affairs of the Czech Republicmzv.gov.cz
Government body responsible for Czech Republic's international relations Focus on security, human rights, prosperity, and good reputation abroad |
815 | |||
| 28 |
Plzeňský Prazdrojprazdroj.cz
Leading Czech beer producer with four breweries exporting to over 50 countries, promoting responsible alcohol consumption through the Responsible Brewers Initiative |
809 | |||
| 29 |
Fincentrumswisslifeselect.cz
A financial advisory company in the Czech and Slovak Republic, part of Swiss Life, offering quality services to clients with a wide range of financial products |
796 | |||
| 30 | 795 | ||||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Prague
- The largest companies in Prague 427
- Financial services firms in Prague 50
- Critical infrastructure operators in Prague 49
- Retail chains in Prague 42
- Companies with in-house R&D in Prague 40
- Companies with a mobile app in Prague 37
- Public sector organisations in Prague 36
- Software Development companies in Prague 34
- Financial Services companies in Prague 33
- Corporate groups and holding companies in Prague 33
- E-commerce companies in Prague 30
- Manufacturers in Prague 30
- SaaS companies in Prague 29
- IT Services and IT Consulting companies in Prague 28
- Professional services firms in Prague 26
- Hardware manufacturers in Prague 25
- IT services companies in Prague 25