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The 65 largest Non-profit Organizations companies in Chicago

Tamtam tracks 65 Non-profit Organizations companies headquartered in Chicago. This list ranks all of them by number of employees on LinkedIn, led by YMCA of the USA, The Y (YMCA) and Alzheimer's Associationยฎ. Their median headcount is 402. Half of them were founded in 1957 or later.

๐Ÿ‡บ๐Ÿ‡ธ Chicago65 companiesUpdated Oct 10, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
YMCA of the USAymca.org

National resource office supporting independent YMCAs across the US by providing leadership, guidance, and resources to strengthen communities and promote youth development, health, and well-being

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 46,444 1851
2
The Y (YMCA)ymca.org

We empower individuals regardless of age, income, or background to reach their full potential, improve well-being, and inspire action in communities

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 27,727 1844
3
Alzheimer's Associationยฎalz.org

Leading organization advancing Alzheimer's research, providing care and support for affected individuals, promoting brain health, and aiming to eliminate dementia.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 2,940 n/a
4
American Marketing Associationama.org

Provides marketing and sales professionals with industry insights, professional certification, academic journals, training, and conferences through a global community.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 2,669 1937
5
American Medical Associationama-assn.org

Providing essential resources and advocacy to support physicians, residents, and medical students throughout their medical careers and improve public health.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 2,513 1847
6
Ronald McDonald Housermhc.org

Provide housing and support services to families with ill or injured children, ensuring proximity to medical care and emotional assistance.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 2,505 1974
7
American College of Surgeonsfacs.org

Dedicated to improving surgical patient care worldwide with membership opportunities, quality programs, surgical registries, and education to enhance outcomes

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,644 1913
8
American Dental Associationada.org

Advocates for dentists, dental science, public oral health. Provides resources for professionals, researches, and champions public health initiatives.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,599 1859
9
Heartland Allianceheartlandalliance.org

Leading human-rights organization empowering individuals to exit poverty, heal from trauma, achieve stability, secure rights, shape policies, and access health, safety, justice, and economic opportunities globally

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,363 1888
10
Muscular Dystrophy Associationmda.org

Leading voluntary health organization supporting people with muscular dystrophy, ALS, advancing research, care, and family advocacy for independence.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,253 1950
11
YMCA of Metropolitan Chicagoymcachicago.org

A longstanding organization offering various centers, camps, and extension sites in Chicago for social guidance and personal empowerment for over 165 years

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,206 1858
12
After School Mattersafterschoolmatters.org

A non-profit organization in Chicago offering after-school and summer programs to high school teens, focusing on skills development and opportunities

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,160 1991
13
Opportunity Internationalopportunity.org

Global non-profit organization equipping individuals with tools to overcome poverty by providing financial resources, training, and support for small business growth and education access

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,067 1971
14
American Lung Associationlung.org

This organization saves lives by improving lung health, preventing lung disease, conducting research, providing education, and advocating for policy changes

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,066 1904
15
Moody Bible Institutemoody.edu

The company equips people globally to grow in spiritual maturity, study the Bible, and share it with compassion, impacting the world for Christ

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 1,014 1886
16
Obama Foundationobama.org

Inspiring and empowering ordinary people to create positive change, connecting them to achieve more together through various initiatives worldwide

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 952 n/a
17
Kappa Alpha Pi Pre-Law & Government Fraternitykapinational.com

This company promotes law knowledge for undergraduates, community service, fraternalism, and integrity within their pre-law co-ed fraternity

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 915 2007
18
Academy of Nutrition and Dieteticsacademylogin.org

A leading organization of food and nutrition professionals dedicated to improving health through research, education, and advocacy, empowering members to be industry leaders

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 859 1917
19
CEDAcedaorg.net

A leading non-profit agency in Cook County, providing a range of services including education, employment, energy conservation, health, and housing counseling to residents

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 839 1966
20
American Library Associationala.org

Advocacy and empowerment for libraries and workers, ensuring equitable information access and promoting professional standards and conduct.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 838 1876
21
American College of Healthcare Executivesache.org

An organization advancing healthcare leadership excellence through lifelong learning, integrity, diversity, and inclusion, offering valuable knowledge, networking opportunities, and professional development

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 734 1913
22
Smithbucklinsmithbucklin.com

Providing comprehensive association management, event coordination, educational programming, and strategic consulting to modernize operations, advance organizational missions, and deliver enhanced member value.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 708 1949
23
HIMSShimss.org

A global non-profit organization advising and transforming the health ecosystem through expertise in innovation, policy, workforce development, research, and analytics

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 702 n/a
24
Feeding Americafeedingamerica.org

Largest network of food banks and meal programs serving over 40 million people, focusing on food rescue and hunger relief.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 699 1967
25
ASCMascm.org

Global leader in supply chain transformation, talent development, and innovation Offers education, certification, resources, and community for professionals driving sustainable operations worldwide

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 561 2018
26
Institute of Food Technologists (IFT)ift.org

Advancing food science globally to ensure safe, nutritious, and sustainable food supply through collaboration, innovation, and dedication to scientific integrity and progress

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 525 1939
27
Youth Guidanceyouth-guidance.org

Youth Guidance implements school-based programs to support at-risk children in overcoming obstacles, focusing on education, and succeeding in life

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 505 1924
28
Ada S. McKinley Community Services, Incadasmckinley.org

Empowering individuals through education, employment, and community support services to change lives and strengthen communities in Illinois/Chicago and beyond

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 484 1919
29
Start Earlystartearly.org

A nonprofit organization advancing quality early learning and care for families with children, providing doula services, home visiting, and Head Start programs

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 460 1982
30
Academy of General Dentistryagd.org

Professional association of 40,000 general dentists providing quality dental care and oral health education to the public in the United States

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 458 n/a
31
American Society for Clinical Pathology (ASCP)ascp.org

A professional organization for pathologists and laboratory professionals, providing education, certification, and advocacy for patients and the industry since 1922

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 443 1922
32
RE:WORK TRAININGreworktraining.org

re:WORK TRAINING helps overlooked talent become confident sales professionals through modernized hiring processes, diverse tech training, and tailored solutions for success

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 442 2016
33
International Interior Design Associationiida.org

Global association supporting commercial interior design professionals and industry affiliates in creating inclusive, impactful designs for a more equitable world

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 402 1994
34
National Able Networknationalable.org

A non-profit organization providing personalized career support through counseling, training, and placement services for disadvantaged job seekers across multiple states

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 401 1977
35
Envision Unlimitedenvisionunlimited.org

Provider of diverse care services for individuals with disabilities of all ages, focusing on independence, inclusion, and community integration in Chicagoland and Central Illinois

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 398 1948
36
Jewish United Fundjuf.org

This organization provides human services, Jewish experiences, and strengthens community connections for Jews and others in need locally and globally

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 383 1900
37
PCMApcma.org

Global community for Business Events Strategists providing education, networking, knowledge sharing, and market intelligence for informed business decisions in the events sector

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 364 1956
38
APICSascm.org

Global leader in supply chain transformation, innovation, and leadership through research, education, and certification programs to elevate supply chain excellence

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 356 1957
39
Appraisal Instituteappraisalinstitute.org

This company is a leading professional association for real estate appraisers, promoting ethical practices, professional education, and advocacy programs

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 345 1932
40
Elevateelevatenp.org

The company designs programs to provide clean and affordable heat, power, and water to all individuals and communities, regardless of location or income

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 329 2000
41
Treatment Alternatives for Stronger Communitiestasc.org

A social impact organization providing specialized case management to empower individuals in overcoming barriers, finding recovery, and reshaping destinies for thriving communities

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 321 1976
42
i.c.stars |* Chicagoicstars.org

Creating economic opportunities for underserved communities by training young adults in tech skills and connecting them with high growth sectors

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 319 1998
43
PAWS Chicagopawschicago.org

A national leader in No Kill animal sheltering, PAWS Chicago helps reduce homeless pet euthanasia, finds homes for pets, and provides essential medical services

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 312 1997
44
DRI | Association of Lawyers Defending Businessdri.org

An international organization of attorneys focused on defending business and individuals in civil litigation, providing education, resources, and networking opportunities in the legal community

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 309 1960
45
CARCcarc.info

Provides quality services for individuals with developmental disabilities and special needs, promoting independence, choice, and community integration through various programs and support services

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 284 1964
46
Easterseals serving Chicagoland and Greater Rockfordeastersealschicago.org

A nonprofit organization serving Chicagoland and Greater Rockford, providing educational and community support to individuals of all abilities since 1936

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 259 1936
47
Young Inventor Entrepreneurs Program - YiEP Youth Programchuffed.org

The organization supports gifted young minds in STEM by providing educational programs, equipment kits, and mentorship to inspire innovation in Chicago communities

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 238 n/a
48
Carole Robertson Center for Learningcarolerobertsoncenter.org

Nonprofit organization providing comprehensive child and family development programs to educate, enrich, and empower children and families in Chicago

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 205 1976
49
American Student Dental Associationasdanet.org

A national student organization advocating for the rights and interests of dental students, promoting lifelong involvement in organized dentistry

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 202 1971
50
Marillac St. Vincentmarillacstvincent.org

Providing early childhood education, youth enrichment, and community outreach services to strengthen and empower individuals since 1914

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 183 1914
51
The Latino Medical Student Associationnational.lmsa.net

Recruiting and supporting healthcare professionals dedicated to improving healthcare access and delivery for Hispanic/Latino communities and underserved populations through various initiatives and collaborations

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 179 n/a
52
World Bicycle Reliefworldbicyclerelief.org

A global non-profit organization mobilizing rural communities worldwide with life-changing bicycles to expand access to education, healthcare, and economic opportunities

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 170 2005
53
Chicago Urban Leaguechiul.org

The organization works to achieve equity for Black families and communities through social and economic empowerment since 1916

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 170 1916
54
El Valorelvalor.org

A non-profit organization providing bilingual rehabilitation, early childhood learning, youth enrichment, and leadership development programs to support urban families and individuals with disabilities

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 164 1973
55
The Resurrection Projectresurrectionproject.org

Building trusting relationships to educate and empower individuals, immigrants, and families to achieve social and economic aspirations, stable homes, and community participation

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 164 1990
56
Sunshine Enterprisessunshineenterprises.com

Empowering high-potential entrepreneurs in under-resourced communities through business training and support, fostering economic self-sufficiency and community development Apply now!

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 159 2012
57
National Association for Healthcare Qualityยฎ (NAHQยฎ)nahq.org

Established in 1976, NAHQ is a leading organization for healthcare quality professionals, providing certification, educational programs, networking, and career resources

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 158 1976
58
Instituto del Progreso Latinoinstitutochicago.org

Provides education, training, employment, and support services for Latino immigrants and families, fostering full participation in US society while preserving cultural identity.

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 156 n/a
59
Lydia Home Associationlydiahome.org

A Chicago-based organization providing hope, healing, and home to foster children by offering a holistic approach to recovery and family restoration

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 155 1916
60
Erie Neighborhood Houseeriehouse.org

A Chicago-based nonprofit supporting immigrant and low-income families through education, wellness, community programs, legal services, and advocacy for social change

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 155 1870
61
BUILD Chicagobuildchicago.org

The company provides at-risk youth in Chicago with alternatives to gang violence, focusing on positive youth development and leadership skills

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 152 1969
62
Campbell & Companycampbellcompany.com

A national nonprofit consulting firm specializing in helping organizations increase impact through fundraising, communications, executive search, and strategic information services

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 150 1976
63
Interfaith Americainterfaithamerica.org

Inspiring, empowering, and connecting individuals and institutions to embrace and leverage America's religious diversity for a more inclusive society

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 150 2002
64
Turnaround Management Associationturnaround.org

The international non-profit association specializes in corporate renewal and turnaround management, with over 8,300 members worldwide in 55 chapters

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 150 1988
65
Chicago Youth Centerschicagoyouthcenters.org

Providing high-quality early learning and out-of-school enrichment programs for children in under-resourced neighborhoods to support holistic development and bright futures

Non-profit Organizations ๐Ÿ‡บ๐Ÿ‡ธ Chicago 149 1956

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 10, 2026.

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