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List of companies with in-house R&D in Chicago

Tamtam tracks 93 companies with in-house R&D headquartered in Chicago. This list ranks the 30 largest by number of employees on LinkedIn, led by McDonald's, JLL and Mondel膿z International. Their median headcount is 7,202. Half of them were founded in 1919 or later.

馃嚭馃嚫 Chicago30 companiesUpdated Nov 11, 2026

This selection of companies in Chicago with in-house R&D capabilities features large enterprises across diverse sectors. McDonald's, a global fast-food chain, and JLL, a real estate and investment management firm, represent significant employers. Other major players include Mondel膿z International, known for snack brands like Oreo, and GE HealthCare, an innovator in medical technology. ADM, a global nutrition company, and Kraft Heinz, a producer of food and beverage products, also highlight Chicago's strong presence in the food industry.

The list reveals a notable concentration of companies in the food and beverage manufacturing and services sectors, alongside a substantial presence of healthcare institutions. For example, Rush University Medical Center and UChicago Medicine are academic medical centers. The technology sector is also represented by companies like Motorola Solutions, focused on public safety communication, and Motorola Mobility, known for innovative smartphones.

#CompanyIndustryHeadquarters EmployeesFounded
1
McDonald'scorporate.mcdonalds.com

global fast-food restaurant chain operating over 37,000 locations worldwide, serving popular menu items and employing 1.9 million people

Restaurants 馃嚭馃嚫 Chicago 261,219 n/a
2
JLLjill.com

A leading professional services firm specializing in real estate and investment management, creating rewarding opportunities and sustainable solutions using advanced technology

Real Estate 馃嚭馃嚫 Chicago 104,899 n/a
3
Mondel膿z Internationalmondelezinternational.com

Global multinational manufacturing and marketing iconic snacks, biscuits, chocolate, candy, and gum brands including Oreo and Cadbury to empower people to snack right.

Food and Beverage Manufacturing 馃嚭馃嚫 Chicago 79,000 2012
4
GE HealthCaregehealthcare.com

Global medical technology and digital solutions innovator leveraging intelligent devices, data analytics, and artificial intelligence to drive precision health and improve patient outcomes worldwide

Hospitals and Health Care 馃嚭馃嚫 Chicago 60,041 1892
5
ADMadm.com

Global nutrition company transforming industries with plant-based solutions, sustainable practices, and cutting-edge innovations for a healthier, more environmentally friendly future

Food and Beverage Manufacturing 馃嚭馃嚫 Chicago 42,789 1902
6
Kraft Heinzkraftheinz.com

Producer of high-quality food and beverage products including condiments, dairy, meals, beverages, and nutrition items marketed worldwide.

Food and Beverage Services 馃嚭馃嚫 Chicago 39,000 2015
7
Motorola Solutionsmotorolasolutions.com

The company builds and connects technologies to enhance public safety collaboration for safer communities, schools, hospitals, and businesses worldwide

Telecommunications 馃嚭馃嚫 Chicago 28,153 n/a
8
University of Chicagouchicago.edu

A prestigious academic institution encouraging scholars and students to think critically, explore various disciplines, and challenge conventional ideas for global enrichment

Higher Education 馃嚭馃嚫 Chicago 18,526 n/a
9
Motorola Mobility (a Lenovo Company)motorola.com

Innovative smartphones and accessories are created by a global team, fostering collaboration, creativity, and a commitment to consumer-centric mobile technology innovation

Computers and Electronics Manufacturing 馃嚭馃嚫 Chicago 17,456 1928
10
TransUniontransunion.com

Global information and insights company enabling trust and confident transactions by providing actionable, data-driven pictures of individuals for businesses and consumers worldwide

IT Services and IT Consulting 馃嚭馃嚫 Chicago 17,036 n/a
11
Rush University Medical Centerrush.edu

Academic medical center with hospital, health center, university offering medical, nursing education, research, residency programs, and community outreach services.

Hospitals and Health Care 馃嚭馃嚫 Chicago 12,484 n/a
12
UChicago Medicineuchicagomedicine.org

Provides superior, compassionate healthcare, advancing medical innovation, serving community health needs, and furthering knowledge through an academic medical institution and regional network.

Hospitals and Health Care 馃嚭馃嚫 Chicago 7,940 1927
13
Conagra Brandsconagrabrands.com

Diverse team managing iconic and emerging food brands with a focus on innovation, integrity, and consistent business results.

Food and Beverage Services 馃嚭馃嚫 Chicago 7,846 1919
14
Northwestern Memorial Hospitalnmh.org

A collaboration between healthcare and university partners, Northwestern Medicine aims to transform healthcare through research, teaching, and patient care excellence

Hospitals and Health Care 馃嚭馃嚫 Chicago 7,371 n/a
15
Ann & Robert H. Lurie Children's Hospital of Chicagoluriechildrens.org

Largest pediatric healthcare provider in the region, teaching partner of Northwestern University, nationally ranked in all pediatric specialties.

Hospitals and Health Care 馃嚭馃嚫 Chicago 7,202 n/a

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16
Kellanovakellanova.com

A global powerhouse in snacks, cereal, noodles, and frozen foods, committed to creating better days and promoting sustainable access to food

Food and Beverage Manufacturing 馃嚭馃嚫 Chicago 6,197 2023
17
USGusg.com

A leading manufacturer of building products, providing innovative solutions for walls, ceilings, flooring, and roofing in construction markets worldwide

Wholesale Building Materials 馃嚭馃嚫 Chicago 5,752 1902
18
Ferraraferrarausa.com

A leading sugar confectionery company in the US, focused on driving category development with a diverse portfolio of iconic brands

Food and Beverage Manufacturing 馃嚭馃嚫 Chicago 5,430 1908
19
James Hardiejameshardie.com

Global leader in high-performance fiber cement and fiber gypsum building solutions, empowering homeowners and professionals worldwide with premium quality products for design and protection

Wholesale Building Materials 馃嚭馃嚫 Chicago 5,022 n/a
20
Northwestern University - The Feinberg School of Medicinefeinberg.northwestern.edu

A renowned medical school in Chicago offering MD programs, research, patient care, and community service to educate future physicians

Higher Education 馃嚭馃嚫 Chicago 4,009 1859
21
Amsted Industriesamsted.com

Global manufacturer of industrial components for railroad, automotive, commercial vehicle, construction, and building markets, with a focus on innovation and employee ownership

Industrial Machinery Manufacturing 馃嚭馃嚫 Chicago 3,554 n/a
22
Tempus AItempus.com

Utilizing AI and data analytics, the company empowers physicians to personalize patient care with real-time insights and targeted therapies

Biotechnology Research 馃嚭馃嚫 Chicago 3,051 2015
23
Methode Electronicsmethode.com

Designs, engineers, produces mechatronic products for OEMs, utilizing broad technologies for user interface, LED lighting, power distribution, and sensor applications.

Appliances, Electrical, and Electronics Manufacturing 馃嚭馃嚫 Chicago 3,043 n/a
24
JBT Mareljbtmarel.com

Provider of integrated technology, equipment, software, and services for food and beverage industries, supporting diverse product sectors worldwide.

Machinery Manufacturing 馃嚭馃嚫 Chicago 2,852 1884
25
Applied Systemswww1.appliedsystems.com

A leading provider of innovative cloud software for the insurance industry, driving transformation through digitization, automation, and new partnerships

Software Development 馃嚭馃嚫 Chicago 2,813 1983
26
UI Healthhospital.uillinois.edu

This academic health enterprise in Illinois offers comprehensive care, education, and research to promote health equity and train healthcare leaders

Hospitals and Health Care 馃嚭馃嚫 Chicago 2,813 n/a
27
S&C Electric Companysandc.com

This company specializes in developing innovative solutions for a more intelligent and resilient electrical grid, aiming for an outage-free, sustainable energy future

Electrical Equipment Manufacturing 馃嚭馃嚫 Chicago 2,761 1911
28
GE Transportation, a Wabtec companywabteccorp.com

A global leader in digital industrial solutions for rail, mining, marine, power, and drilling industries, specializing in advanced manufacturing and connected machines

Truck Transportation 馃嚭馃嚫 Chicago 2,533 1907
29
DRWdrw.com

Global principal trading firm capturing investment opportunities through technology and research across multiple asset classes while maintaining a collaborative, high-performance culture for employees.

Financial Services 馃嚭馃嚫 Chicago 2,463 n/a
30
Shirley Ryan AbilityLabsralab.org

Specializes in treating severe physical disabilities through integrated clinical care and research, improving recovery for complex conditions.

Hospitals and Health Care 馃嚭馃嚫 Chicago 2,124 1954

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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