Non-profit Organizations companies headquartered in Massachusetts (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	edc.org edc.org A global nonprofit focused on improving education, promoting health, and expanding economic opportunity through innovative programs in over 80 countries	Non-profit Organizations	🇺🇸 Waltham	4,310	1958
2	Year Up United yearup.org Provides young adults from diverse backgrounds with training and opportunities to access meaningful careers, addressing workforce talent gaps and economic inequity.	Non-profit Organizations	🇺🇸 Boston	3,976	2000
3	Sanctuary sanctuary.co.uk A not-for-profit housing association providing affordable homes and care in England and Scotland, aiming to build sustainable communities	Non-profit Organizations	🇺🇸 Worcester	3,510	1969
4	JSI jsi.org Support underserved communities worldwide through health management consulting, research, training, and capacity building for effective public health solutions.	Non-profit Organizations	🇺🇸 Boston	3,272	1978
5	City Year linktr.ee Organization supporting students and schools with diverse teams of AmeriCorps members, improving academic outcomes and fostering civic engagement in communities nationwide and internationally	Non-profit Organizations	🇺🇸 Boston	2,920	1988
6	Clinton Health Access Initiative, Inc.clintonhealthaccess.org Global health organization improving health outcomes in low- and middle-income countries by strengthening health systems and negotiating price reductions for drugs and health tools	Non-profit Organizations	🇺🇸 Boston	2,274	2002
7	Management Sciences for Health msh.org Health organization partnering globally to strengthen health systems and improve access to quality care for vulnerable populations through local solutions and sustainable practices	Non-profit Organizations	🇺🇸 Medford	2,119	1971
8	BSC bridgew.edu Student focused on learning corporate communications, including media relations, public speaking, and organizational communication strategies for business environments.	Non-profit Organizations	🇺🇸 Franklin	1,894	n/a
9	Advocates advocates.org A company that supports individuals dealing with developmental, mental health, or life challenges by providing creative solutions and empowering them to thrive	Non-profit Organizations	🇺🇸 Framingham	1,799	1975
10	YMCA of Greater Boston ymcaboston.org A leading social services provider in MA offering health and wellness programs, child care, summer camp, youth sports, teen leadership, workforce development, and community outreach	Non-profit Organizations	🇺🇸 Boston	1,175	n/a
11	Hult Prize Foundation hultprize.org Inspiring young entrepreneurs worldwide to tackle global challenges by creating impactful startups aligned with UN Sustainable Development Goals	Non-profit Organizations	🇺🇸 Cambridge	1,087	n/a
12	Northeast Arc ne-arc.org This organization provides a wide range of services for people with disabilities and autism, as well as children at risk, and their families in Massachusetts	Non-profit Organizations	🇺🇸 Danvers	917	1954
13	Bay Cove Human Services baycovehumanservices.org Provides services for individuals and families facing challenges of developmental disabilities, aging, mental illness, and addiction in Greater Boston and southeastern Massachusetts	Non-profit Organizations	🇺🇸 Boston	883	1974
14	NFPA nfpa.org A global nonprofit organization focused on preventing death, injury, and property loss from fire, electrical, and related hazards through codes, standards, research, education, and advocacy	Non-profit Organizations	🇺🇸 Quincy	830	1896
15	Millennium Campus Network (MCN)millenniumfellows.org A global student network providing training and connections to undergraduates working on social impact projects to address humanity's greatest challenges	Non-profit Organizations	🇺🇸 Boston	811	2007
16	Road Scholar roadscholar.org The not-for-profit organization offers educational travel adventures for older adults worldwide to inspire learning, discovery, and cultural experiences	Non-profit Organizations	🇺🇸 Boston	793	1975
17	The Home for Little Wanderers thehome.org The organization provides support and care for vulnerable children through various programs to ensure their well-being and bright futures	Non-profit Organizations	🇺🇸 Boston	793	1799
18	WORK Inc.workinc.org A New England agency supporting individuals with disabilities to live fulfilling lives by providing necessary support services	Non-profit Organizations	🇺🇸 Dorchester	744	1965
19	NACA - Neighborhood Assistance Corporation of America naca.com A non-profit organization advocating for economic justice through home ownership, offering affordable mortgage options and assistance with loan modifications	Non-profit Organizations	🇺🇸 Boston	710	1988
20	Old Colony YMCA oldcolonyymca.org A nonprofit organization providing health and wellness programs for all ages, focusing on youth development, community outreach, and support for at-risk populations in Southeastern Massachusetts	Non-profit Organizations	🇺🇸 Brockton	632	1887
21	Mass Audubon massaudubon.org A leading conservation organization in New England addressing biodiversity loss, inequitable access to nature, and climate change through advocacy and education programs	Non-profit Organizations	🇺🇸 Lincoln	581	1896
22	JA Worldwide jaworldwide.org A global youth-serving NGO delivering hands-on learning in entrepreneurship, work readiness, and financial health, reaching millions of young people annually	Non-profit Organizations	🇺🇸 Boston	549	1919
23	Action for Boston Community Development, Inc.bostonabcd.org A nonprofit organization in Boston area providing tools for disadvantaged residents to transition from poverty to stability and success	Non-profit Organizations	🇺🇸 Boston	523	1962
24	The Bridgespan Group bridgespan.org A global nonprofit advising social change leaders to address economic and social barriers, promoting equity and helping communities thrive	Non-profit Organizations	🇺🇸 Boston	509	2000
25	Fidelity Charitable®fidelitycharitable.org A public charity providing donor-advised fund program, supporting nonprofits with $845 billion in grants to make philanthropy accessible and effective	Non-profit Organizations	🇺🇸 Boston	506	1991
26	Pine Street Inn pinestreetinn.org A leading provider of housing, shelter, outreach, and job training in Greater Boston, helping homeless individuals on the path to permanent housing and independence	Non-profit Organizations	🇺🇸 Boston	499	1969
27	YMCA of the North Shore northshoreymca.org An inclusive organization on the North Shore, nurturing kids, promoting healthy living, and fostering social responsibility through multiple YMCA locations	Non-profit Organizations	🇺🇸 Beverly	492	1858
28	Oxfam America oxfamamerica.org Provides crisis support, advocates economic justice, gender equality, climate action, collaborates with local organizations worldwide to combat inequality.	Non-profit Organizations	🇺🇸 Boston	465	1970
29	W3C w3.org An international organization led by Web inventor Tim Berners-Lee, dedicated to developing Web standards in collaboration with members and the public	Non-profit Organizations	🇺🇸 Wakefield	442	1994
30	YouthBuild Global youthbuild.org Partnering with opportunity youth to develop skills and confidence through education, job training, and community leadership programs, fostering lifelong growth and success	Non-profit Organizations	🇺🇸 Roxbury	433	1978
31	South Middlesex Opportunity Council (SMOC)smoc.org A multi-service organization providing behavioral health, housing, employment, education, family, and nutrition services to low-income individuals and families in communities	Non-profit Organizations	🇺🇸 Framingham	428	1965
32	Appalachian Mountain Club outdoors.org This organization promotes outdoor protection, enjoyment, and understanding They strive for healthy natural resources and a central role of the outdoors in people's lives	Non-profit Organizations	🇺🇸 Boston	418	1876
33	People Incorporated peopleincfr.org A human service agency in Southeastern Massachusetts providing diverse supports and services for individuals of all abilities to strengthen the community	Non-profit Organizations	🇺🇸 Fall River	404	1968
34	North American Family Institute nafi.com A comprehensive organization offering mental health, addiction, child welfare, and rehabilitative programs to support individuals and families in achieving personal goals and thriving in their communities	Non-profit Organizations	🇺🇸 Stoneham	401	1974
35	World Education worlded.org Dedicated to improving global health, education, and socioeconomic equity for individuals and communities through projects in over 50 countries since 1951	Non-profit Organizations	🇺🇸 Boston	387	1951
36	Community Teamwork commteam.org This organization works to strengthen communities, reduce poverty, and provide vital services through collaboration and creating opportunities for economic independence and personal growth	Non-profit Organizations	🇺🇸 Lowell	366	n/a
37	The Key Program, Inc key.org This organization offers support and services to troubled youth and their families, focusing on positive life skills, quality care, and community safety	Non-profit Organizations	🇺🇸 Westborough	356	1974
38	Facing History & Ourselves facinghistory.org This organization uses history to educate and inspire students to stand up against bigotry and hate, promoting empathy, equity, and justice	Non-profit Organizations	🇺🇸 Boston	350	1976
39	Boys and Girls Clubs of Boston bgcb.org The organization provides a safe environment, mentorship, and programs to help young people reach their full potential as responsible citizens and leaders	Non-profit Organizations	🇺🇸 Boston	342	1893
40	HomeStart homestart.org An innovative nonprofit in Greater Boston working to end and prevent homelessness through eviction prevention, housing search assistance, and housing stability support services	Non-profit Organizations	🇺🇸 Boston	331	1994
41	South Shore YMCA ssymca.org A nonprofit organization dedicated to empowering children, promoting health, and fostering community responsibility through various programs and services	Non-profit Organizations	🇺🇸 Quincy	324	n/a
42	NTI nticentral.org This nonprofit organization supports disabled individuals and caregivers with advocacy, workforce development, and economic empowerment through work-at-home job opportunities and support services	Non-profit Organizations	🇺🇸 Boston	317	1995
43	AgeSpan agespan.org The company provides a range of home-based care, community support, and assisted living programs to help older adults in Massachusetts maintain independence and dignity	Non-profit Organizations	🇺🇸 Lawrence	315	1974
44	The Learning Center for the Deaf tlcdeaf.org A national leader in educational and therapeutic services for deaf and hard of hearing individuals, providing knowledge, opportunity, and empowerment	Non-profit Organizations	🇺🇸 Framingham	295	1970
45	Kennedy-Donovan Center kdc.org A nonprofit organization providing support to individuals with developmental delays, disabilities, and family challenges through various programs and services	Non-profit Organizations	🇺🇸 Foxboro	249	1969
46	Pathlight servicenet.org An organization founded by mothers in 1952 dedicated to serving individuals with intellectual disabilities through innovative programs and family services	Non-profit Organizations	🇺🇸 Springfield	248	1952
47	The Community Group thecommunitygroupinc.org A private nonprofit organization offering various educational programs including early childhood, charter schools, consulting, and child care resources since 1970	Non-profit Organizations	🇺🇸 Lawrence	222	1970
48	MHA (Mental Health Association)linktr.ee Aiming to be a premier provider of residential and support services, committed to innovation, creating equal opportunities, and improving individuals' lives	Non-profit Organizations	🇺🇸 Chicopee	219	1960
49	Upstream USA upstream.org The company is dedicated to improving availability and affordability of patient-centered contraceptive care in collaboration with healthcare leaders nationwide	Non-profit Organizations	🇺🇸 Boston	209	2014
50	The Governor's Academy thegovernorsacademy.org The organization is the oldest boarding school in New England, shaping student leaders for a successful future and emphasizing civic responsibility	Non-profit Organizations	🇺🇸 Byfield	186	1763
51	Free Software Foundation fsf.org Non-profit supporting free software movement, promoting universal freedom to distribute and modify computer software, based in Boston, USA	Non-profit Organizations	🇺🇸 Boston	186	1985
52	MetroWest YMCA metrowestymca.org A nonprofit organization focused on promoting overall wellness through various programs and services for individuals in the community	Non-profit Organizations	🇺🇸 Framingham	185	1959
53	Merrimack Valley YMCA mvymca.org A diverse organization with branches, camps, and programs in the Merrimack Valley, focused on promoting healthier lives for all	Non-profit Organizations	🇺🇸 Lawrence	183	n/a
54	Big Brother Big Sister Foundation, Inc.bbbsfoundation.org A non-profit organization that turns gently worn goods into cash to support mentoring programs for children in Massachusetts Learn more at wwwbbbsfoundationorg	Non-profit Organizations	🇺🇸 Holbrook	183	1997
55	Community Servings servings.org A not-for-profit program in Massachusetts providing nutritious meals and support to individuals and families living with critical illnesses like HIV/AIDS, Cancer, and more	Non-profit Organizations	🇺🇸 Boston	180	1990
56	Soccer Without Borders soccerwithoutborders.org Utilizing soccer to empower refugee and immigrant youth through team-based programs, education, and cultural exchange for personal growth and success	Non-profit Organizations	🇺🇸 Boston	174	2006
57	South Shore Elder Services sselder.org A non-profit organization providing services for elderly and disabled individuals in 11 cities in Massachusetts, promoting independence and community living	Non-profit Organizations	🇺🇸 Braintree	174	1977
58	Social Finance socialfinance.org A national impact finance and advisory nonprofit that creates partnerships and investments to improve outcomes in education, economic mobility, health, and housing	Non-profit Organizations	🇺🇸 Boston	169	2011
59	Precision Development (PxD)precisiondev.org Global non-profit using technology and data to empower people in poverty, improve livelihoods, mitigate risks, and promote sustainability in developing countries through mobile information services	Non-profit Organizations	🇺🇸 Boston	168	2016
60	The Possible Zone possiblezone.org An experiential learning program in Boston for young adults, focusing on developing an entrepreneurial spirit, skills, and networks for workforce readiness	Non-profit Organizations	🇺🇸 Boston	166	2010
61	Bread of Life breadoflifemalden.org A non-profit organization serving north of Boston, providing food and support to the hungry, homeless, and isolated with a faith-based mission	Non-profit Organizations	🇺🇸 Malden	166	n/a
62	The Guild for Human Services guildhumanservices.org A non-profit organization providing education, support, and residential services for individuals with disabilities, recognized for innovative leadership and excellence in care	Non-profit Organizations	🇺🇸 Concord	163	1945
63	Reach Out and Read bit.ly A nonprofit organization promoting early literacy by providing new books to children, encouraging parents to read aloud for school readiness	Non-profit Organizations	🇺🇸 Boston	163	1989
64	Big Brothers Big Sisters of Eastern Massachusetts emassbigs.org This organization matches adult mentors with children to provide support, guidance, and positive relationships for improved outcomes in school and life	Non-profit Organizations	🇺🇸 Boston	160	n/a
65	Nonotuck Resource Associates, Inc.nonotuck.com A Massachusetts-based organization providing Adult Family Care, Shared Living, and Day Services for individuals with disabilities, supporting over 450 families	Non-profit Organizations	🇺🇸 Northampton	158	1972
66	Morgan Memorial Goodwill Industries goodwillmass.org A nonprofit organization providing job training, work opportunities, and low-cost goods to help individuals achieve independence and dignity through work	Non-profit Organizations	🇺🇸 Boston	157	1895
67	RefugePoint refugepoint.org RefugePoint seeks lasting solutions for highly vulnerable refugees by identifying and protecting those with no other means for survival	Non-profit Organizations	🇺🇸 Boston	155	2005
68	Verité verite.org Global nonprofit fighting labor rights violations and human trafficking, working with corporations to ensure safe, fair, and legal conditions in global supply chains	Non-profit Organizations	🇺🇸 Northampton	154	1995
69	Xaverian Brothers High School xbhs.com A Catholic college-preparatory school for boys, focused on integrating spiritual, moral, intellectual, and social development to prepare graduates for higher education and service	Non-profit Organizations	🇺🇸 Westwood	154	1963
70	YMCA of Central Massachusetts ymcaofcm.org Offering a wide range of services including gyms, pools, preschool, summer camp, and high school programming for all ages and interests Join online today!	Non-profit Organizations	🇺🇸 Worcester	154	n/a
71	VentureWell venturewell.org Company focuses on growing, funding, and training STEM innovators and entrepreneurs to tackle global challenges and bring their ideas to impactful solutions	Non-profit Organizations	🇺🇸 Hadley	150	1995
72	International Institute of Buffalo iibuffalo.org Improving the lives of immigrants and refugees in Western New York through community-based initiatives and resources	Non-profit Organizations	🇺🇸 Burlington	150	1918
73	Heading Home headinghomeinc.org Dedicated to ending homelessness in Greater Boston by providing housing and critical services like life skills, financial literacy, and job training	Non-profit Organizations	🇺🇸 Boston	150	1974
74	CHOICES 4choices.org This company creates a safe and supportive recovery community for adolescents with addiction and co-occurring disorders to reclaim their lives	Non-profit Organizations	🇺🇸 Worcester	149	n/a
75	Boys & Girls Club of Worcester bgcworcester.org This company aims to help youth, especially those facing challenges, become responsible citizens and leaders through supportive relationships and mentorship	Non-profit Organizations	🇺🇸 Worcester	40	1889
76	The Future Society thefuturesociety.org A nonprofit organization working to improve AI governance in the US and Europe to ensure alignment with societal needs	Non-profit Organizations	🇺🇸 Boston	38	2014
77	HEET linktr.ee The company develops equitable and efficient climate solutions that reduce carbon emissions through innovative approaches	Non-profit Organizations	🇺🇸 Boston	22	2008

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Non-profit Organizations companies headquartered in Massachusetts

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