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The 50 largest companies with in-house R&D in Gelderland

Tamtam tracks 101 companies with in-house R&D headquartered in Gelderland. This list ranks the 50 largest by number of employees on LinkedIn, led by Nexperia, Radboudumc and Alliander. Their median headcount is 724. Half of them were founded in 1966 or later. The most common headquarters are Nijmegen (10), Apeldoorn (7) and Arnhem (7).

πŸ‡³πŸ‡± Gelderland50 companiesUpdated Nov 13, 2026

These Gelderland companies with in-house R&D are primarily large organizations in healthcare, education, and food production. Notable examples include Nexperia, a global semiconductor company, Radboudumc, an academic medical center, and Wageningen University & Research, which focuses on healthy food and living environments. Alliander is a Dutch energy network company, while Royal De Heus specializes in animal nutrition products, and Plukon Food Group produces poultry and alternative proteins.

The data shows a strong concentration of headquarters in Nijmegen, Arnhem, and Apeldoorn. Many of these entities, such as Wageningen University & Research (founded 1918) and Royal De Heus (founded 1917), have a long history, indicating well-established institutions and businesses in the region.

#CompanyIndustryHeadquarters EmployeesFounded
1
Nexperianexperia.com

Global semiconductor company with expertise in essential component development, serving diverse industries worldwide, committed to innovation, efficiency, and sustainability

Semiconductor Manufacturing πŸ‡³πŸ‡± Nijmegen 12,000 n/a
2
Radboudumcradboudumc.nl

Leading academic center for medical science, education, and patient care; connecting research, education, and patient care for future healthcare and medical science.

Hospitals and Health Care πŸ‡³πŸ‡± Nijmegen 9,995 1956
3
Allianderalliander.com

A Dutch energy network company responsible for distributing gas and electricity, promoting sustainable energy solutions, and ensuring equal access to reliable energy

Utilities πŸ‡³πŸ‡± Arnhem 9,523 2009
4
Wageningen University & Researchwur.nl

Education and research focused on healthy food and living environments, combining natural and social sciences for practical scientific breakthroughs.

Research Services πŸ‡³πŸ‡± Wageningen 9,227 1918
5
Radboud Universityru.nl

A public university in Nijmegen, Netherlands known for its research focus, established in 1923, offering seven faculties and serving over 19,130 students

Research Services πŸ‡³πŸ‡± Nijmegen 7,525 1923
6
Pro Personapropersona.nl

A major employer in healthcare, providing treatment, support, and new perspectives to improve quality of life and contribute to community safety

Mental Health Care πŸ‡³πŸ‡± Wolfheze 2,627 n/a
7
Gelre ziekenhuizengelreziekenhuizen.nl

A large hospital in the Netherlands with a focus on improvement, innovation, education, and research, serving a region with multiple facilities

Hospitals and Health Care πŸ‡³πŸ‡± Apeldoorn 2,602 n/a
8
Royal De Heusdeheus.com

A global family-owned company providing safe, healthy animal nutrition products and knowledge to help farmers worldwide in sustainable food production

Animal Feed Manufacturing πŸ‡³πŸ‡± Ede 2,153 1917
9
Politieacademiepolitieacademie.nl

The company focuses on training, research, and knowledge development for police officers, working with students, practitioners, and international partners to build a strong future for law enforcement

Public Safety πŸ‡³πŸ‡± Apeldoorn 2,126 n/a
10
Ziekenhuis Gelderse Valleigeldersevallei.nl

Dedicated to knowledge and focused on health, this hospital offers a wide range of medical specialties with a strong emphasis on nutrition and exercise

Hospitals and Health Care πŸ‡³πŸ‡± Ede 1,911 n/a
11
Plukon Food Groupplukon.com

An innovative European producer of foods, specializing in fresh, sustainable poultry, vegetarian, and alternative protein products for supermarkets and quick-service restaurants

Food and Beverage Manufacturing πŸ‡³πŸ‡± Wezep 1,693 1894
12
Royal Agrifirm Groupagrifirm.com

Collaborates with farmers and partners to develop innovative, sustainable agricultural methods ensuring healthy soil, animals, nature, and fair farmer income.

Farming πŸ‡³πŸ‡± Apeldoorn 1,430 1892
13
Synthonsynthon.com

An international pharmaceutical company specializing in developing and manufacturing high-quality generic medicines to improve global health and increase access to affordable treatments

Pharmaceutical Manufacturing πŸ‡³πŸ‡± Nijmegen 1,337 1991
14
Nedapnedap.com

Development and implementation of digital twin technology across healthcare, livestock, retail, and security sectors to create sustainable, innovative solutions.

IT Services and IT Consulting πŸ‡³πŸ‡± Groenlo 1,299 1929
15
ArtEZ University of the Artsartez.nl

A diverse, international community focused on artistic, intellectual, and personal growth through inspiring art education and leading artistic research

Higher Education πŸ‡³πŸ‡± Arnhem 1,296 n/a
16
Teijin Aramidteijinaramid.com

Global leader in high-performance aramid fiber, specializing in innovative solutions for diverse industries, driving sustainability and collaboration for a better future

Chemical Manufacturing πŸ‡³πŸ‡± Arnhem 1,171 1983
17
Planonplanonsoftware.com

Provider of Smart Sustainable Building Management software connecting buildings, people, and processes to create efficient, engaging, and sustainable spaces for all stakeholders

IT Services and IT Consulting πŸ‡³πŸ‡± Nijmegen 1,150 1982
18
Citocito.nl

With over 50 years of experience, we develop tests and exams with a focus on equal opportunities in education, offering advice and services Contact us via phone, email, or social media

Education Administration Programs πŸ‡³πŸ‡± Arnhem 1,057 n/a
19
Karakter kinder- en jeugdpsychiatriekarakter.com

An academic center specializing in child and adolescent psychiatry providing diagnosis and treatment for various psychiatric disorders, offering therapies, medication, and research-based care

Mental Health Care πŸ‡³πŸ‡± Ede 991 1967
20
CRVcrv4all.com

CRV specializes in cattle improvement through genetic products, on-farm services, and digital information They provide solutions for farmers worldwide

Ranching πŸ‡³πŸ‡± Arnhem 971 1874
21
VMI Groupvmi-group.com

Global leader in tire manufacturing machinery, providing technical innovations and support to keep manufacturers ahead in their markets worldwide

Machinery Manufacturing πŸ‡³πŸ‡± Epe 961 1945
22
BDR Thermea Groupbdrthermeagroup.com

Manufacture and supply of sustainable heating technologies including heat pumps, hybrid and hydrogen boilers to reduce carbon emissions globally.

Appliances, Electrical, and Electronics Manufacturing πŸ‡³πŸ‡± Apeldoorn 849 n/a
23
Ampleonampleon.com

A global leader in RF power technology, Ampleon specializes in high frequency applications using GaN and LDMOS technologies to drive innovation and success for customers worldwide

Semiconductor Manufacturing πŸ‡³πŸ‡± Nijmegen 842 2015
24
Weener Plastics Groupsilgandispensing.com

A global supplier of sustainable plastic packaging solutions for various markets, designing and manufacturing caps, closures, bottles, and jars Headquartered in The Netherlands with 25 facilities worldwide

Packaging and Containers Manufacturing πŸ‡³πŸ‡± Ede 828 1953
25
AWLawl.nl

Global machine builder specializing in smart automation solutions for various industries, fostering a collaborative and inclusive work environment for over 750 employees worldwide

Automation Machinery Manufacturing πŸ‡³πŸ‡± Harderwijk 724 1993

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26
Nijhuis Saur Industriesnijhuissaurindustries.com

Providing sustainable water use solutions, energy and resource recovery, engineering, consultancy, project execution, and mobile water services worldwide.

Environmental Services πŸ‡³πŸ‡± Doetinchem 641 1904
27
Nederlands Instituut Publieke Veiligheid (NIPV)nipv.nl

The IFV strengthens fire services, disaster response, and crisis management for safety regions through policy support, expertise, and research

Higher Education πŸ‡³πŸ‡± Arnhem 639 n/a
28
Royal Kaakkaak.com

Specializing in bakery technology since 1846, offering standalone machines and integrated solutions for automated bakery lines, meeting and exceeding customer expectations

Machinery Manufacturing πŸ‡³πŸ‡± Terborg 630 1846
29
MARIN (Maritime Research Institute Netherlands)marin.nl

Global institute for hydrodynamic and nautical research, offering integrated solutions for clean, smart, and safe shipping, promoting sustainability and innovation in the maritime sector

Research Services πŸ‡³πŸ‡± Wageningen 629 1929
30
Bronkhorstbronkhorst.com

Manufacturer of Mass Flow and Pressure Meters/Controllers for gases and liquids with worldwide presence, focus on innovation, quality, and customer satisfaction

Automation Machinery Manufacturing πŸ‡³πŸ‡± Ruurlo 614 1981
31
Rademaker BVrademaker.com

Design and supply of efficient, automated bakery production lines for breads, pastries, pizza, and other dough-based products worldwide.

Machinery Manufacturing πŸ‡³πŸ‡± Culemborg 555 1977
32
Barenbrug Groupbarenbrug.com

Developing a wide range of grass varieties for various purposes, including cattle feed, parks, lawns, sports fields, and recreation areas

Biotechnology Research πŸ‡³πŸ‡± Nijmegen 537 1904
33
Symeressymeres.com

Leading transatlantic CRO with 600 scientists offering solutions for drug discovery and development, from hit finding to clinical API delivery Innovative and client-focused

Biotechnology Research πŸ‡³πŸ‡± Nijmegen 507 1987
34
Royal SMIT Transformers B.V.werkenbij.sgb-smit.group

A transformer specialist in Europe, designing and producing large power transformers, reactors, and more with innovative technology for nearly 100 years

Industrial Machinery Manufacturing πŸ‡³πŸ‡± Nijmegen 501 1913
35
Remeharemeha.nl

A Dutch company specializing in innovative and energy-efficient heating products for homes and businesses, part of an international group with a wide presence

Manufacturing πŸ‡³πŸ‡± Apeldoorn 461 1935
36
Intero Integrityintero-integrity.com

Provider of inspection, industrial, and environmental services for the energy industry, ensuring compliant and efficient operations with a turn-key mindset

Public Safety πŸ‡³πŸ‡± Tricht 443 1985
37
Besi Netherlands B.V.besi.com

A product division of a publicly listed company, develops and manufactures semiconductor machines under the Fico brand, serving global chip manufacturers and suppliers

Semiconductor Manufacturing πŸ‡³πŸ‡± Duiven 419 n/a
38
Pompestichtingpompestichting.nl

The company provides treatment, care, and security to individuals involved with the justice system, focusing on crime prevention and safe reintegration into society

Mental Health Care πŸ‡³πŸ‡± Nijmegen 413 1966
39
De Heus Brasil NutriΓ§Γ£o Animaldeheus.com.br

A global family-owned company providing sustainable animal nutrition solutions to help producers worldwide progress in the agricultural sector

Farming πŸ‡³πŸ‡± Ede 401 1911
40
Leo Kannerhuisyouz.nl

Specialist treatment center for individuals with autism and psychiatric/behavioral issues, offering personalized and online care, research, and digital tools development

Mental Health Care πŸ‡³πŸ‡± Arnhem 381 1974
41
Arco - We are Arco, we make tablesarco.nl

A family business designing and manufacturing tables, chairs, and furniture accessories with a focus on craftsmanship, innovation, and local materials

Furniture and Home Furnishings Manufacturing πŸ‡³πŸ‡± Winterswijk 368 n/a
42
Bredenoordbredenoord.com

This company provides energy solutions to ensure successful entrepreneurship, especially in uncertain situations worldwide, enabling customers to operate guaranteed

Electric Power Generation πŸ‡³πŸ‡± Apeldoorn 359 1937
43
Itho Daalderopithodaalderop.nl

The company develops and manufactures innovative solutions for heating, hot water, ventilation, and control technology, aiming to create a healthy, comfortable, and energy-efficient indoor climate

Mechanical Or Industrial Engineering πŸ‡³πŸ‡± Tiel 335 1880
44
JBT Marel Meatjbtmarel.com

Global leader in providing integrated systems and advanced processing equipment to the red meat industry, optimizing productivity and enhancing meat product quality worldwide

Machinery Manufacturing πŸ‡³πŸ‡± Lichtenvoorde 332 1983
45
Aeresaeres.nl

A multifaceted institution in the green sector offering education, research, commercial activities, and international projects in sustainable learning and production

Education πŸ‡³πŸ‡± Ede 332 2004
46
Rappitrappit.io

Expert in developing Enterprise Software modernization solutions on Google Cloud Platform and Java technologies, specializing in manufacturing, supply chain, logistics, retail industries

Software Development πŸ‡³πŸ‡± Putten 328 2009
47
Linthorstlinthorst.world

One of the largest total installers in the Netherlands, specializing in technical solutions for the built environment and industry through close collaboration and a focus on long-term relationships

Construction πŸ‡³πŸ‡± Apeldoorn 326 1978
48
Wageningen Food Safety Researchwur.nl

Specialized in food safety research, this institute advises governments, conducts independent analysis, and serves as a reference laboratory for various substances

Research Services πŸ‡³πŸ‡± Wageningen 326 1975
49
Cyclomediacyclomedia.com

Transforms real world data into valuable insights with 360Β° street-level visualizations and AI-powered analytics for smarter decision-making in urban environments and corporate sectors

Data Infrastructure and Analytics πŸ‡³πŸ‡± Zaltbommel (NL) 314 1980
50
NEDCONnedcon.com

A global leader in storage systems, specializing in complex and automated warehouse layouts with in-house development and a commitment to exceeding expectations

Transportation, Logistics, Supply Chain and Storage πŸ‡³πŸ‡± Doetinchem 307 1969

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 13, 2026.

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