These large organizations in South Holland are notable for their in-house R&D capabilities, spanning diverse sectors. Examples include Wolters Kluwer, a global leader in professional information and software, and Erasmus MC, a university medical center focused on advanced healthcare and research. Damen is a maritime company providing innovative shipbuilding solutions, while Mammoet offers global lifting and transport engineering services. TNO is an independent organization specializing in applied research.
A significant concentration of these R&D-focused entities is found in The Hague, which hosts numerous government administration bodies like Rijkswaterstaat and Centraal Bureau voor de Statistiek, as well as educational institutions and healthcare providers. Rotterdam also features prominently, with companies such as IMCD Group in chemical manufacturing and Rotterdam University of Applied Sciences.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Wolters Kluwerwolterskluwer.com
Global leader in professional information and software solutions across healthcare, tax, finance, legal, and corporate sectors, serving customers worldwide |
22,177 | |||
| 2 |
Erasmus MCerasmusmc.nl
Leading university medical center providing advanced healthcare, cutting-edge research, and high-quality education focused on complex and rare medical conditions. |
14,228 | |||
| 3 |
Rijkswaterstaatrijkswaterstaat.nl
Rijkswaterstaat is responsible for managing and developing roads, waterways, and water resources to create a sustainable living environment in the Netherlands |
12,088 | |||
| 4 |
Leiden University Medical Centerlumc.nl
A medical center focused on improving patient care through scientific research, providing specialized treatments, and serving as a referral center for complex medical questions |
8,812 | |||
| 5 |
Parnassia Groepparnassiagroep.nl
A healthcare group with 8,000 employees providing mental health services in three core regions, offering comprehensive care tailored to individual needs |
8,302 | |||
| 6 | 6,070 | ||||
| 7 | 5,866 | ||||
| 8 |
Mammoetmammoet.com
Global company offering lifting, transporting, installing, and decommissioning solutions for a wide range of projects with a focus on efficiency and safety |
5,183 | |||
| 9 |
Rotterdam University of Applied Scienceshogeschoolrotterdam.nl
Higher professional education institution with 30,000 students, combining practical experience and knowledge to prepare for future careers. |
5,163 | |||
| 10 |
IMCD Groupimcdgroup.com
Global leader in distributing and formulating specialty chemicals and ingredients across various industries, collaborating with partners to provide innovative solutions worldwide |
4,057 | |||
| 11 |
De Haagse Hogeschool / The Hague University of Applied Sciencesdehaagsehogeschool.nl
Higher education institution offering a variety of programmes to over 20,000 students from 140+ countries, prioritizing inclusion, sustainability, and internationality |
3,564 | |||
| 12 |
Haaglanden Medisch Centrum (HMC)haaglandenmc.nl
A leading hospital in The Hague region, providing specialized care across three locations with a focus on oncology, elderly care, and trauma services |
3,038 | |||
| 13 |
Inter IKEA Groupikea.com
A diverse group of individuals passionate about home furnishing, working together to create a better everyday life for many people worldwide |
2,938 | |||
| 14 | 2,859 | ||||
| 15 |
Centraal Bureau voor de Statistiekcbs.nl
A data collection and processing agency that publishes statistics for practical use, policymaking, and research, covering various societal aspects |
2,786 | |||
| 16 | 2,462 | ||||
| 17 |
Caldiccaldic.com
The company provides innovative and sustainable solutions in life science and material science markets, with a focus on food, pharma, personal care, and industrial formulations |
2,189 | |||
| 18 |
Reinier de Graaf ziekenhuisreinierdegraaf.nl
With a history of providing healthcare for almost eight centuries, the company operates hospitals and expert centers, focusing on various medical specialties and patient demographics |
2,144 | |||
| 19 |
Aramco Overseas Companyaramcooverseas.com
A global energy and chemicals leader with European offices driving innovation, research, and safe energy delivery worldwide for over 60 years |
2,137 | |||
| 20 |
ARLANXEOarlanxeo.com
A global synthetic rubber company specializing in high-performance rubber for automotive, tire, construction, and oil & gas industries Owned by Saudi Aramco |
2,014 | |||
| 21 |
GGZ Rivierduinenrivierduinen.nl
A large mental health organization in the Netherlands offering a range of services for adults, elderly, youth, and children, including clinical treatment and polyclinic help |
1,972 | |||
| 22 |
Rijk Zwaanrijkzwaan.com
A family-owned company developing and selling improved fruit and vegetable varieties globally, with a focus on innovation, research, and quality |
1,933 | |||
| 23 | 1,905 | ||||
| 24 |
Hunter Douglas Europehunterdouglasgroup.com
A global leader in window coverings and architectural products, focusing on innovative, high-quality solutions for homes and commercial buildings worldwide |
1,785 | |||
| 25 |
Rotterdam School of Management, Erasmus Universityrsm.nl
A top-ranked business school in Europe offering education and research to develop international business leaders with an innovative mindset for a sustainable future |
1,474 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 26 | 1,444 | ||||
| 27 | 1,371 | ||||
| 28 |
Huismanhuismanequipment.com
Designs and manufactures heavy construction equipment for renewable energy, oil and gas, civil, naval, and entertainment industries, setting new industry standards since 1929 |
1,280 | |||
| 29 |
Fokker Technologies Holding B.V.gknaerospace.com
Design and manufacture of aerostructures, electrical wiring systems, landing gear, and aerospace services integrated within a global aerospace company. |
1,270 | |||
| 30 |
GGZ Delflandggz-delfland.nl
A longstanding mental health institution providing personalized care to individuals of all ages, offering a range of services across multiple locations |
1,211 | |||
| 31 | 1,046 | ||||
| 32 |
Koppertkoppert.com
Providing natural pest control, pollination, and biostimulant products to improve crop health, resilience, and sustainable farming worldwide. |
1,004 | |||
| 33 |
Pharming Grouppharming.com
Develops and commercializes innovative medicines including small molecules and biologics for patients living with rare, debilitating, and life-threatening diseases globally. |
865 | |||
| 34 |
D眉mmen Orangelatam.dummenorange.com
Global leader in breeding and propagating flowers and plants, offering patented varieties to growers worldwide with a century-long legacy and innovative R&D Employing 6,600 people globally |
773 | |||
| 35 |
Netherlands Forensic Institute NFIforensischinstituut.nl
providing reliable forensic information and products to support national and international organizations in peace, justice, and safety efforts |
758 | |||
| 36 | 695 | ||||
| 37 |
AnywhereNowanywhere.now
Offers a Microsoft Teams-native Dialogue Management solution to streamline contact center operations, enhance customer experience, and boost productivity through AI and efficient collaboration. |
569 | |||
| 38 |
VPSvpsveritas.com
A global leader in maritime decarbonisation advisory services, providing innovative testing and inspection solutions to optimize performance while reducing environmental impact |
561 | |||
| 39 | 556 | ||||
| 40 |
Provimicargill.com
Specializing in feed solutions for various species with innovative research, technical knowledge, and customized options, backed by global network and expertise in animal nutrition |
554 | |||
| 41 |
Royal Van Lent Shipyardwerkenbijfeadship.nl
A historic yacht construction company specializing in custom-built motoryachts, with highly skilled craftsmen, premium facilities, and a focus on maintaining personal relationships with owners |
552 | |||
| 42 |
Sint Franciscus Gasthuisfranciscus.nl
A leading hospital in Rotterdam providing multidisciplinary care, specialized treatment, and collaboration with regional healthcare providers, focusing on patient-centered services |
535 | |||
| 43 |
IHE Delft Institute for Water Educationun-ihe.org
Global graduate water education and training provider based in the Netherlands, focused on sustainable water management and capacity building for global development |
478 | |||
| 44 |
DORC Dutch Ophthalmic Research Center (International)dorcglobal.com
Supplier of advanced equipment, instruments, and liquids for ophthalmic surgery, enhancing surgical precision and improving global eye care. |
471 | |||
| 45 |
Quookerquooker.com
Innovative company specializing in developing and producing cutting-edge boiling water taps for modern kitchens, with a focus on efficiency and design |
469 | |||
| 46 |
Het Oogziekenhuis Rotterdamoogziekenhuis.nl
A leading eye care specialist in the Netherlands, prioritizing patient safety, innovation, and high-quality treatments in a comforting environment |
468 | |||
| 47 |
RH Marinerhmarine.com
RH Marine is a leading system integrator providing tailored electrical and automation solutions for Defence, Safety & Security ships and Yachts since 1860 |
457 | |||
| 48 |
Stokvis Tapes Groupstokvistapes.com
Innovative partner in adhesive solutions, offering custom products for various industries with global presence and expertise in tape manufacturing |
453 | |||
| 49 |
Centre for Human Drug Researchchdr.nl
A Dutch CRO specializing in data-intensive early phase clinical studies, prioritizing subjects' safety and comfort while supporting medical education |
403 | |||
| 50 |
Ortec Financeortecfinance.com
Provides advanced software models and technology for investment decision making, risk management, and financial planning to global financial institutions. |
399 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 15, 2026.
More company lists in South Holland
- The largest companies in South Holland 2,508
- Multinational companies in South Holland 559
- Transportation, Logistics, Supply Chain and Storage companies in South Holland 276
- Logistics companies in South Holland 263
- Retail chains in South Holland 188
- Critical infrastructure operators in South Holland 152
- Truck Transportation companies in South Holland 145
- Professional services firms in South Holland 145
- Software Development companies in South Holland 142
- SaaS companies in South Holland 137
- Manufacturers in South Holland 134
- Family-owned companies in South Holland 128
- Healthcare providers in South Holland 124
- IT Services and IT Consulting companies in South Holland 121
- Financial services firms in South Holland 120
- Education providers in South Holland 111
- Hospitals and Health Care companies in South Holland 109
- Financial Services companies in South Holland 107
- Consulting firms in South Holland 106
- Distributors and wholesalers in South Holland 96
- IT services companies in South Holland 93
- Hardware manufacturers in South Holland 86
- Hotel and hospitality groups in South Holland 86
- Public sector organisations in South Holland 82
The same list elsewhere in Netherlands
- Companies with in-house R&D in the Netherlands 738
- Companies with in-house R&D in North Holland 188
- Companies with in-house R&D in Gelderland 101
- Companies with in-house R&D in North Brabant 97
- Companies with in-house R&D in Overijssel 41
- Companies with in-house R&D in Limburg 29
- Companies with in-house R&D in Amsterdam 129
- Companies with in-house R&D in Eindhoven 29
- Companies with in-house R&D in Rotterdam 26
- Companies with in-house R&D in Utrecht 26