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List of companies with in-house R&D in South Holland

Tamtam tracks 140 companies with in-house R&D headquartered in South Holland. This list ranks the 50 largest by number of employees on LinkedIn, led by Wolters Kluwer, Erasmus MC and Rijkswaterstaat. Their median headcount is 1,474. Half of them were founded in 1959 or later. The most common headquarters are Rotterdam (13), The Hague (8) and Delft (4).

馃嚦馃嚤 South Holland50 companiesUpdated Nov 15, 2026

These large organizations in South Holland are notable for their in-house R&D capabilities, spanning diverse sectors. Examples include Wolters Kluwer, a global leader in professional information and software, and Erasmus MC, a university medical center focused on advanced healthcare and research. Damen is a maritime company providing innovative shipbuilding solutions, while Mammoet offers global lifting and transport engineering services. TNO is an independent organization specializing in applied research.

A significant concentration of these R&D-focused entities is found in The Hague, which hosts numerous government administration bodies like Rijkswaterstaat and Centraal Bureau voor de Statistiek, as well as educational institutions and healthcare providers. Rotterdam also features prominently, with companies such as IMCD Group in chemical manufacturing and Rotterdam University of Applied Sciences.

#CompanyIndustryHeadquarters EmployeesFounded
1
Wolters Kluwerwolterskluwer.com

Global leader in professional information and software solutions across healthcare, tax, finance, legal, and corporate sectors, serving customers worldwide

Software Development 馃嚦馃嚤 Alphen aan den Rijn 22,177 1836
2
Erasmus MCerasmusmc.nl

Leading university medical center providing advanced healthcare, cutting-edge research, and high-quality education focused on complex and rare medical conditions.

Hospitals and Health Care 馃嚦馃嚤 Rotterdam 14,228 2002
3
Rijkswaterstaatrijkswaterstaat.nl

Rijkswaterstaat is responsible for managing and developing roads, waterways, and water resources to create a sustainable living environment in the Netherlands

Government Administration 馃嚦馃嚤 The Hague 12,088 1894
4
Leiden University Medical Centerlumc.nl

A medical center focused on improving patient care through scientific research, providing specialized treatments, and serving as a referral center for complex medical questions

Hospitals and Health Care 馃嚦馃嚤 Leiden 8,812 n/a
5
Parnassia Groepparnassiagroep.nl

A healthcare group with 8,000 employees providing mental health services in three core regions, offering comprehensive care tailored to individual needs

Mental Health Care 馃嚦馃嚤 The Hague 8,302 2007
6
Damendamen.com

This maritime company provides innovative solutions for trade, energy, and recreation, focusing on sustainability, efficiency, and collaboration to benefit future generations globally

Shipbuilding 馃嚦馃嚤 Gorinchem 6,070 n/a
7
TNOtno.nl

An independent organization specializing in applied research, connecting people and knowledge to drive innovations for industry competitiveness and societal well-being sustainably

Research Services 馃嚦馃嚤 2595 DA The Hague 5,866 1932
8
Mammoetmammoet.com

Global company offering lifting, transporting, installing, and decommissioning solutions for a wide range of projects with a focus on efficiency and safety

Engineering Services 馃嚦馃嚤 Schiedam 5,183 1807
9
Rotterdam University of Applied Scienceshogeschoolrotterdam.nl

Higher professional education institution with 30,000 students, combining practical experience and knowledge to prepare for future careers.

Higher Education 馃嚦馃嚤 Rotterdam 5,163 1988
10
IMCD Groupimcdgroup.com

Global leader in distributing and formulating specialty chemicals and ingredients across various industries, collaborating with partners to provide innovative solutions worldwide

Chemical Manufacturing 馃嚦馃嚤 Rotterdam 4,057 1995
11
De Haagse Hogeschool / The Hague University of Applied Sciencesdehaagsehogeschool.nl

Higher education institution offering a variety of programmes to over 20,000 students from 140+ countries, prioritizing inclusion, sustainability, and internationality

Higher Education 馃嚦馃嚤 The Hague 3,564 1987
12
Haaglanden Medisch Centrum (HMC)haaglandenmc.nl

A leading hospital in The Hague region, providing specialized care across three locations with a focus on oncology, elderly care, and trauma services

Hospitals and Health Care 馃嚦馃嚤 The Hague 3,038 1873
13
Inter IKEA Groupikea.com

A diverse group of individuals passionate about home furnishing, working together to create a better everyday life for many people worldwide

Furniture and Home Furnishings Manufacturing 馃嚦馃嚤 Delft 2,938 1989
14
Lelylely.com

Providing innovative solutions and tailored services for dairy farms, including milking, cleaning, and farm management advice since 1948.

Machinery Manufacturing 馃嚦馃嚤 Maassluis 2,859 1948
15
Centraal Bureau voor de Statistiekcbs.nl

A data collection and processing agency that publishes statistics for practical use, policymaking, and research, covering various societal aspects

Government Administration 馃嚦馃嚤 The Hague 2,786 1899
16
ICT Groupict.eu

Leading European provider industrial technology solutions. Delivers consultancy, software development, project solutions, managed services across vital sectors: automotive, high tech, industry, infrastructure, logistics, public mobility and safety.

IT Services and IT Consulting 馃嚦馃嚤 Barendrecht 2,462 n/a
17
Caldiccaldic.com

The company provides innovative and sustainable solutions in life science and material science markets, with a focus on food, pharma, personal care, and industrial formulations

Chemical Manufacturing 馃嚦馃嚤 Rotterdam 2,189 n/a
18
Reinier de Graaf ziekenhuisreinierdegraaf.nl

With a history of providing healthcare for almost eight centuries, the company operates hospitals and expert centers, focusing on various medical specialties and patient demographics

Hospitals and Health Care 馃嚦馃嚤 Delft 2,144 1252
19
Aramco Overseas Companyaramcooverseas.com

A global energy and chemicals leader with European offices driving innovation, research, and safe energy delivery worldwide for over 60 years

Oil and Gas 馃嚦馃嚤 The Hague 2,137 1948
20
ARLANXEOarlanxeo.com

A global synthetic rubber company specializing in high-performance rubber for automotive, tire, construction, and oil & gas industries Owned by Saudi Aramco

Chemical Manufacturing 馃嚦馃嚤 The Hague 2,014 2016
21
GGZ Rivierduinenrivierduinen.nl

A large mental health organization in the Netherlands offering a range of services for adults, elderly, youth, and children, including clinical treatment and polyclinic help

Mental Health Care 馃嚦馃嚤 Leiden 1,972 2005
22
Rijk Zwaanrijkzwaan.com

A family-owned company developing and selling improved fruit and vegetable varieties globally, with a focus on innovation, research, and quality

Food and Beverage Manufacturing 馃嚦馃嚤 De Lier 1,933 1924
23
OMAoma.com

International architecture practice with a research and design studio, led by eight partners, known for innovative buildings worldwide, with offices in multiple cities

Architecture and Planning 馃嚦馃嚤 Rotterdam 1,905 1975
24
Hunter Douglas Europehunterdouglasgroup.com

A global leader in window coverings and architectural products, focusing on innovative, high-quality solutions for homes and commercial buildings worldwide

Consumer Goods 馃嚦馃嚤 Rotterdam 1,785 1919
25
Rotterdam School of Management, Erasmus Universityrsm.nl

A top-ranked business school in Europe offering education and research to develop international business leaders with an innovative mindset for a sustainable future

Higher Education 馃嚦馃嚤 Rotterdam 1,474 1970

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26
Hyvahyva.com

Global provider of transport solutions for commercial vehicle and environmental industries, specializing in hydraulic loading systems, waste handling, and crane products Operates worldwide

Truck Transportation 馃嚦馃嚤 Alphen aan den Rijn 1,444 1979
27
Privapriva.com

This high-tech company develops climate control solutions for various sectors worldwide with a focus on sustainability, efficiency, and innovation

IT Services and IT Consulting 馃嚦馃嚤 De Lier 1,371 1959
28
Huismanhuismanequipment.com

Designs and manufactures heavy construction equipment for renewable energy, oil and gas, civil, naval, and entertainment industries, setting new industry standards since 1929

Industrial Machinery Manufacturing 馃嚦馃嚤 Schiedam 1,280 1929
29
Fokker Technologies Holding B.V.gknaerospace.com

Design and manufacture of aerostructures, electrical wiring systems, landing gear, and aerospace services integrated within a global aerospace company.

Aviation and Aerospace Component Manufacturing 馃嚦馃嚤 Papendrecht 1,270 n/a
30
GGZ Delflandggz-delfland.nl

A longstanding mental health institution providing personalized care to individuals of all ages, offering a range of services across multiple locations

Mental Health Care 馃嚦馃嚤 Delft 1,211 1394
31
ORTECortec.com

A global provider of decision-support software and data science solutions for organizations to improve business results and make a positive impact

Software Development 馃嚦馃嚤 Zoetermeer 1,046 1981
32
Koppertkoppert.com

Providing natural pest control, pollination, and biostimulant products to improve crop health, resilience, and sustainable farming worldwide.

Farming 馃嚦馃嚤 Berkel en Rodenrijs 1,004 1967
33
Pharming Grouppharming.com

Develops and commercializes innovative medicines including small molecules and biologics for patients living with rare, debilitating, and life-threatening diseases globally.

Biotechnology Research 馃嚦馃嚤 Leiden 865 1988
34
D眉mmen Orangelatam.dummenorange.com

Global leader in breeding and propagating flowers and plants, offering patented varieties to growers worldwide with a century-long legacy and innovative R&D Employing 6,600 people globally

Farming 馃嚦馃嚤 De Lier 773 n/a
35
Netherlands Forensic Institute NFIforensischinstituut.nl

providing reliable forensic information and products to support national and international organizations in peace, justice, and safety efforts

Research Services 馃嚦馃嚤 The Hague 758 1999
36
LINETlinet.com

A global leader in advanced care beds manufacturing, providing innovative solutions designed by nurses, with a focus on quality, lifetime value, and customer trust

Medical Equipment Manufacturing 馃嚦馃嚤 Dordrecht 695 1990
37
AnywhereNowanywhere.now

Offers a Microsoft Teams-native Dialogue Management solution to streamline contact center operations, enhance customer experience, and boost productivity through AI and efficient collaboration.

Software Development 馃嚦馃嚤 Rotterdam 569 n/a
38
VPSvpsveritas.com

A global leader in maritime decarbonisation advisory services, providing innovative testing and inspection solutions to optimize performance while reducing environmental impact

Professional Services 馃嚦馃嚤 Rotterdam 561 n/a
39
KONIkoni.com

This company revolutionized the suspension industry with adjustable hydraulic shock absorbers, offering comfort, safety, and innovation for all vehicles

Motor Vehicle Manufacturing 馃嚦馃嚤 Oud-Beijerland 556 1857
40
Provimicargill.com

Specializing in feed solutions for various species with innovative research, technical knowledge, and customized options, backed by global network and expertise in animal nutrition

Farming 馃嚦馃嚤 Rotterdam 554 1927
41
Royal Van Lent Shipyardwerkenbijfeadship.nl

A historic yacht construction company specializing in custom-built motoryachts, with highly skilled craftsmen, premium facilities, and a focus on maintaining personal relationships with owners

Shipbuilding 馃嚦馃嚤 Kaag 552 1849
42
Sint Franciscus Gasthuisfranciscus.nl

A leading hospital in Rotterdam providing multidisciplinary care, specialized treatment, and collaboration with regional healthcare providers, focusing on patient-centered services

Hospitals and Health Care 馃嚦馃嚤 Rotterdam 535 1892
43
IHE Delft Institute for Water Educationun-ihe.org

Global graduate water education and training provider based in the Netherlands, focused on sustainable water management and capacity building for global development

Higher Education 馃嚦馃嚤 Delft 478 1957
44
DORC Dutch Ophthalmic Research Center (International)dorcglobal.com

Supplier of advanced equipment, instruments, and liquids for ophthalmic surgery, enhancing surgical precision and improving global eye care.

Medical Equipment Manufacturing 馃嚦馃嚤 Zuidland 471 1983
45
Quookerquooker.com

Innovative company specializing in developing and producing cutting-edge boiling water taps for modern kitchens, with a focus on efficiency and design

Manufacturing 馃嚦馃嚤 Ridderkerk 469 1970
46
Het Oogziekenhuis Rotterdamoogziekenhuis.nl

A leading eye care specialist in the Netherlands, prioritizing patient safety, innovation, and high-quality treatments in a comforting environment

Hospitals and Health Care 馃嚦馃嚤 Rotterdam 468 1874
47
RH Marinerhmarine.com

RH Marine is a leading system integrator providing tailored electrical and automation solutions for Defence, Safety & Security ships and Yachts since 1860

Shipbuilding 馃嚦馃嚤 Schiedam 457 1860
48
Stokvis Tapes Groupstokvistapes.com

Innovative partner in adhesive solutions, offering custom products for various industries with global presence and expertise in tape manufacturing

Plastics Manufacturing 馃嚦馃嚤 Alblasserdam 453 1956
49
Centre for Human Drug Researchchdr.nl

A Dutch CRO specializing in data-intensive early phase clinical studies, prioritizing subjects' safety and comfort while supporting medical education

Research Services 馃嚦馃嚤 Leiden 403 1987
50
Ortec Financeortecfinance.com

Provides advanced software models and technology for investment decision making, risk management, and financial planning to global financial institutions.

IT Services and IT Consulting 馃嚦馃嚤 Rotterdam 399 1981

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 15, 2026.

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