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List of companies with in-house R&D in Overijssel

Tamtam tracks 41 companies with in-house R&D headquartered in Overijssel. This list ranks all of them by number of employees on LinkedIn, led by University of Twente, Saxion University of Applied Sciences and Windesheim. Their median headcount is 317. Half of them were founded in 1986 or later. The most common headquarters are Enschede (13), Deventer (4) and Zwolle (4).

馃嚦馃嚤 Overijssel41 companiesUpdated Nov 11, 2026

The Overijssel region shows a strong presence of higher education and machinery manufacturing companies with in-house R&D. Key players include the University of Twente, conducting cutting-edge research, and Saxion University of Applied Sciences, offering Bachelor and Master programs. Medisch Spectrum Twente is a top clinical hospital, while Tembo Group provides manufacturing solutions for sustainable alternatives. ITM specializes in solutions for the tobacco industry, and Topicus develops IT solutions for healthcare, education, and finance.

A notable pattern is the concentration of headquarters in Enschede, which hosts several significant institutions like the University of Twente, Saxion University of Applied Sciences, Medisch Spectrum Twente, and Demcon, a firm that develops innovative and complex systems. This indicates a hub for research, education, and advanced engineering within the region.

#CompanyIndustryHeadquarters EmployeesFounded
1
University of Twenteutwente.nl

A forward-thinking university with 3,300 professionals conducting cutting-edge research, driving innovation, and providing inspiring education for over 12,000 students

Research Services 馃嚦馃嚤 Enschede 5,632 1961
2
Saxion University of Applied Sciencessaxion.nl

A university of applied sciences in the Netherlands offering Bachelor and Master programs, short courses, and preparatory courses in English to local and international students

Higher Education 馃嚦馃嚤 Enschede / Deventer / Apeldoorn 4,348 1998
3
Windesheimwindesheim.nl

Provides practice-oriented higher education with 87 study programs, emphasizing international elements and welcoming foreign students and lecturers.

Higher Education 馃嚦馃嚤 Zwolle 3,800 1986
4
Medisch Spectrum Twentemst.nl

A top clinical hospital in Twente offering a wide range of healthcare services, medical education, research, trauma care, and collaboration within a network of hospitals

Hospitals and Health Care 馃嚦馃嚤 Enschede 2,709 n/a
5
Tembo Grouptembo.eu

A global family business with a focus on sustainability, providing manufacturing solutions for sustainable alternatives and innovative cross-over products

Machinery Manufacturing 馃嚦馃嚤 Kampen 1,083 1912
6
ITMtembo.eu

The company specializes in providing comprehensive solutions for the tobacco industry, focusing on high-volume, high-precision platforms for efficient production of innovative products

Machinery Manufacturing 馃嚦馃嚤 Kampen 916 n/a
7
Topicustopicus.nl

The company develops user-friendly IT solutions that benefit healthcare, education, finance, and social sectors, aiming to empower citizens and reduce vulnerability

IT Services and IT Consulting 馃嚦馃嚤 Deventer 812 1998
8
TenCateus.tencatefabrics.com

Design, develop, and produce advanced protective fabrics for professionals in firefighting, military, industry, and energy sectors ensuring safety and comfort.

Textile Manufacturing 馃嚦馃嚤 Nijverdal 755 n/a
9
TKFtkf.nl

A leading supplier of connectivity solutions providing safe and reliable power and data connections worldwide with specialized knowledge, reliability, and service

Manufacturing 馃嚦馃嚤 Haaksbergen 663 1930
10
Voortman Steel Groupcareers.voortman.net

A global steel group focused on modern steel processing machines, innovative software, and services, driven by technology and entrepreneurship

Machinery Manufacturing 馃嚦馃嚤 Rijssen 597 1968
11
PMpm.nl

A family-run company specializes in designing precision linear and rotating bearings, advanced positioning systems, and custom solutions for industries like semiconductor and medical science

Industrial Machinery Manufacturing 馃嚦馃嚤 Dedemsvaart 530 1966
12
Demcondemcon.com

Develops, prototypes, industrializes, and manufactures high-quality, innovative, and complex systems and products, integrating various engineering fields to solve societal and technological challenges.

Engineering Services 馃嚦馃嚤 Enschede 487 1993
13
Voortman Steel Machineryvoortman.net

Design and manufacture CNC steel processing machinery with integrated software solutions, providing automation, optimization, and comprehensive customer support worldwide.

Machinery Manufacturing 馃嚦馃嚤 Rijssen 487 1968
14
VDL Enabling Technologies Group (ETG) Almelovdletg.com

Develop and produce complex, innovative modules and systems. Focused on further development of computer chips, combating diseases, and researching the universe for international clients.

Industrial Machinery Manufacturing 馃嚦馃嚤 Almelo 468 n/a
15
Bizzdesignbizzdesign.com

This company offers enterprise architecture software to improve success rates of enterprise transformation, investment allocation, and risk management for organizations

Software Development 馃嚦馃嚤 Enschede 440 2000
16
Royal GDgddiergezondheid.nl

The company focuses on improving animal health and safety of animal products through veterinary specialists' guidance on disease prevention, animal husbandry, and welfare

Veterinary Services 馃嚦馃嚤 Deventer 436 1919
17
Roessingh, Centrum voor Revalidatieroessingh.nl

Specializing in rehabilitation treatment and care for adults and children with various diagnoses, including stroke, pain, and high spinal cord injuries

Hospitals and Health Care 馃嚦馃嚤 Enschede 407 1948
18
Faculty of Geo-Information Science and Earth Observation (ITC) of the University of Twenteutwente.nl

A leading international knowledge hub in geospatial sciences, specializing in collaborative education and research for solving global challenges with spatial information

Higher Education 馃嚦馃嚤 Enschede 387 1950
19
HITEC Power Protectionhitec-ups.com

Manufacturing turnkey power solutions with dynamic UPS systems using flywheel energy storage, ensuring continuous, conditioned power supply to mission critical processes worldwide

Industrial Machinery Manufacturing 馃嚦馃嚤 Almelo 386 1894
20
Koninklijke Euroma BVeuroma.com

A leading European provider of spice-based solutions for the food industry, specializing in developing tasty, healthy, sustainable, and safe ingredients

Food and Beverage Manufacturing 馃嚦馃嚤 Zwolle 357 1899

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21
Indesindes.eu

Creating successful innovations in Medical Cure, Human Care, and E-mobility by delivering integrated product solutions that improve everyday life

Medical Equipment Manufacturing 馃嚦馃嚤 Enschede 317 1988
22
AHV Internationalahvint.com

Innovative provider of animal health solutions, supporting livestock farmers and veterinarians with natural, scientific animal feeds and expert services for better care results

Biotechnology Research 馃嚦馃嚤 Zwolle 299 2014
23
Brink Groupbrink.eu

Designs and manufactures high-quality towbars for various vehicles, enabling safe and easy towing worldwide with extensive experience.

Motor Vehicle Manufacturing 馃嚦馃嚤 Staphorst 252 1903
24
HoSt Grouphost.nl

A fast-growing family company leading the way in renewable energy generation, specializing in clean conversion technology for sustainable energy solutions globally

Renewable Energy Equipment Manufacturing 馃嚦馃嚤 Enschede 240 1991
25
Bosch Thermotechniek Deventernefit-bosch.nl

In Deventer, part of an international group, Bosch Thermotechniek is a leading provider of heating technology, with expertise in research, production, and sales

Industrial Machinery Manufacturing 馃嚦馃嚤 Deventer 219 1948
26
Aeronamicaeronamic.com

Aeronamic is a leading aerospace company specializing in design, manufacturing, testing, and maintenance of advanced turbomachinery, engine systems, and critical components for aviation

Airlines and Aviation 馃嚦馃嚤 Almelo 214 1988
27
Agrifac Machinery B.V.agrifac.com

Design and manufacture of self-propelled sprayers focusing on economics, ecology, efficiency, and ergonomics for sustainable farming.

Machinery Manufacturing 馃嚦馃嚤 Steenwijk 213 n/a
28
Rollecaterollecate.nl

A leading provider of custom aluminum and steel windows, doors, and complex facade systems for residential and commercial buildings since 1954

Wholesale Building Materials 馃嚦馃嚤 Staphorst 212 1954
29
Beaphar B.V.beaphar.com

Develops manufactures pharmaceuticals, healthcare products, and super premium complete foods for all types of pets, improving their lives for over 80 years.

Pharmaceutical Manufacturing 馃嚦馃嚤 Raalte 177 1943
30
SELOselo.com

Provider of food and animal feed processing equipment and systems, offering stand-alone machines, turnkey production lines, tailor-made installations, and after-sales support

Machinery Manufacturing 馃嚦馃嚤 Hengelo 148 1944
31
DGS Processing Solutionsdgs-ps.com

Designs, manufactures, installs, and maintains highly automated systems and lines for primary meat processing and product handling, including robotics.

Industrial Machinery Manufacturing 馃嚦馃嚤 Haaksbergen 108 2014
32
TKH Grouptkhgroup.com

A leading technology company focusing on innovative systems in Smart Vision, Manufacturing, and Connectivity, aiming to improve efficiency, sustainability, safety, and security globally

Automation Machinery Manufacturing 馃嚦馃嚤 Haaksbergen 103 n/a
33
Alltech Coppensalltechcoppens.com

Provides aquaculture feed solutions for all farmed fish stages, focusing on nutrition, health, and sustainable feed production technology, maximizing farm performance.

Food and Beverage Manufacturing 馃嚦馃嚤 Helmond 92 1993
34
QuiX Quantumquixquantum.com

Building photonic quantum computers designed for scalability, data-center readiness, and the path toward fault-tolerant quantum computing through integrated photonics and quantum optics.

Computer Hardware Manufacturing 馃嚦馃嚤 Enschede 72 2019
35
De Dessert Meesterslinktr.ee

A Dutch company creates unique ice cream desserts with high-quality ingredients and innovative flavors, available in 26 European countries

Food and Beverage Manufacturing 馃嚦馃嚤 Oldenzaal 42 1925
36
OneThirdonethird.io

The company utilizes optical sensors and AI to predict produce spoilage, helping retailers reduce food waste and improve inventory management

IT Services and IT Consulting 馃嚦馃嚤 Enschede 33 2019
37
Datacadabra BVdatacadabra.nl

Develops data science and artificial intelligence for practical applications, saving time and costs through smart, scalable solutions for various organizations.

IT Services and IT Consulting 馃嚦馃嚤 Enschede 17 2015
38
Davines Group - Netherlands | Certified B Corpdavinesgroup.com

A family-owned group producing high-end hair and skin care products, promoting a holistic, sustainable lifestyle with a focus on beauty, ethics, and sustainability globally

Personal Care Product Manufacturing 馃嚦馃嚤 Deventer 13 n/a
39
Hitec Food Systems B.V.hitecbv.nl

A company with 35 years of experience specializing in developing and producing stainless steel process solutions for the food industry

Food and Beverage Manufacturing 馃嚦馃嚤 Zwolle 12 2005
40
Spectro-AIspectroai.ai

Designs and develops AI solutions, software and hardware, for detecting and analyzing objects and areas from sky (drone) and space (satellite).

Software Development 馃嚦馃嚤 Enschede 8 2018
41
Intelligent Data & Internet Of Thingstheidiotcompany.eu

The company provides intelligent data and secure sensor solutions to businesses, aiming to bring control and insight while reducing environmental impact

IT Services and IT Consulting 馃嚦馃嚤 Enschede 2 2016

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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