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50 leading critical infrastructure operators in Iowa

Tamtam tracks 50 critical infrastructure operators headquartered in Iowa. This list ranks all of them by number of employees on LinkedIn, led by Principal Financial Group, Wells Fargo Home Mortgage and UnityPoint Health. Their median headcount is 819. Half of them were founded in 1938 or later. The most common headquarters are Des Moines (15), West Des Moines (5) and Cedar Rapids (4).

๐Ÿ‡บ๐Ÿ‡ธ Iowa50 companiesUpdated Oct 24, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
Principal Financial Groupprincipal.com

Provides retirement planning, investment management, and insurance products globally to help individuals and businesses build long-term wealth and achieve overall financial security.

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 24,405 1879
2
Wells Fargo Home Mortgagewellsfargo.com

A retail mortgage lender providing construction, renovation, home buying, refinancing, jumbo, adjustable-rate, and reverse mortgages to homeowners and homebuyers

Banking ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 13,964 n/a
3
UnityPoint Healthunitypoint.org

Not-for-profit health system providing hospital, clinic, and home health services across Iowa, Illinois, and Wisconsin with patient-centered care.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ West Des Moines 10,341 1995
4
MercyOnemercyone.org

Integrated system of hospitals and clinics providing accessible care, training caregivers, and improving community well-being with a dedication to compassion, transformation, and trust

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 7,091 n/a
5
University of Iowa Health Careuihealthcare.org

Academic medical center delivering innovative education, pioneering research, and exceptional patient care with a focus on collaboration and equity.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Iowa City 6,789 1904
6
Mercy Cedar Rapidsmercycare.org

Provider of personalized healthcare services with advanced technologies, dedicated staff, and compassionate philosophy for patients and employees in Iowa

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Cedar Rapids 4,878 1900
7
CRST The Transportation Solution, Inc.crst.com

A transportation and logistics company founded in 1955, offering solutions such as team expedited, flatbed, dedicated services, and home delivery

Truck Transportation ๐Ÿ‡บ๐Ÿ‡ธ Cedar Rapids 3,730 1955
8
F&Gfglife.com

Established in 1959, headquartered in Des Moines, Iowa, providing unique life insurance and annuity solutions nationwide with a focus on financial security

Insurance ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 2,406 1959
9
MidAmerican Energy Companymidamericanenergy.com

Energy company serving over 15 million customers in Iowa, Illinois, Nebraska, and South Dakota, providing timely and relevant information on energy-related topics

Utilities ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 2,295 n/a
10
TMC Transportationtmctrans.com

A leading employee-owned flatbed carrier and logistics provider offering efficient transportation solutions for a variety of freight nationwide

Truck Transportation ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 2,226 1972
11
Wellmark Blue Cross and Blue Shieldwellmark.com

This company provides health coverage to over 2 million members in Iowa and South Dakota, part of a national network insuring over 100 million people

Insurance ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 2,195 1939
12
EMC Insurance Companiesemcinsurance.com

Provides property and casualty insurance products and services across the United States with a focus on workersโ€™ compensation protection.

Insurance ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 2,149 1911
13
Atheneathene.com

Provides retirement income and savings products, fixed annuities, reinsurance, and institutional pension solutions across multiple countries.

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ West Des Moines 2,049 n/a
14
Genesis Health Systemmercyone.org

Comprehensive healthcare services including hospitals, home health, hospice, primary care, specialty clinics, senior living, and medical equipment across Eastern Iowa and Western Illinois.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Davenport 1,652 1869
15
Sammons Financial Group Companiessammonsfinancialgroup.com

A privately held financial group providing life insurance, annuities, and retirement products with a values-based culture and commitment to communities

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ West Des Moines 1,603 n/a
16
UNIVERSITY OF IOWA HOSPITALS &CLINCS

A medical practice company located in Iowa City, Iowa, providing healthcare services at the University of Iowa Hospitals & Clinics on Hawkins Drive

Medical Practices ๐Ÿ‡บ๐Ÿ‡ธ Iowa City 1,204 n/a
17
UnityPoint Health - St. Luke'sunitypoint.org

This company, known for connecting with communities, is no longer active but you can learn more about their mission on their official LinkedIn page

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Sioux City 1,094 1966
18
UFG Insuranceufginsurance.com

An insurance company founded in 1946, offering property and casualty coverage in all 50 states through independent agencies with an A- rating from AM Best

Insurance ๐Ÿ‡บ๐Ÿ‡ธ Cedar Rapids 1,032 1946
19
Iowa Department of Transportationiowadot.gov

A transportation organization in Iowa focused on safety, customer service, leadership, and integrity to improve lives through transportation

Government Administration ๐Ÿ‡บ๐Ÿ‡ธ Ames 999 n/a
20
Heartland Expressheartlandexpress.com

A leading transportation and logistics provider offering collaborative truckload solutions to top shippers, focused on improving customer satisfaction and supply chain value

Truck Transportation ๐Ÿ‡บ๐Ÿ‡ธ North Liberty 975 1978
21
Mary Greeley Medical Centermgmc.org

A 220-bed regional referral center in central Iowa providing high-quality, cost-effective healthcare services with a focus on specialized care and personal touch

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Ames 851 1916
22
Iowa Department of Health and Human Serviceshhs.iowa.gov

State government agency in Iowa providing quality programs and services to enhance health and resilience of individuals, families, and communities

Government Administration ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 850 1972
23
Broadlawns Medical Centerbroadlawns.org

A leading medical center with over 100 physicians and 1,200 employees, providing high-quality healthcare through various services and training programs

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 838 1924
24
Great River Healthgreatriverhealth.org

Regional health care system providing high-quality services in southeast Iowa, west-central Illinois, and northeast Missouri through hospitals, clinics, pharmacies, and medical equipment & supplies

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ West Burlington 830 1895
25
Care Initiativescareinitiatives.org

Iowa's largest not-for-profit provider offering transitional health care services including skilled nursing, rehabilitation, long term care, and hospice care

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ West Des Moines 819 1989
26
Mercy Medical Center - Des Moinesmercyone.org

A not-for-profit Catholic health care provider in Des Moines operating multiple hospitals, employing 7,000 staff members and serving as a major referral center

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 817 1893
27
GreenState Credit Uniongreenstate.org

Financial cooperative offering diverse services with over $10 billion in assets and 400,000 members, open to those in Iowa and Illinois Counties

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ North Liberty 805 1938
28
The Iowa Cliniciowaclinic.com

A large multi-specialty physician group in Central Iowa offering leading-edge healthcare and exceptional customer service through partnership with local medical centers

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ West Des Moines 763 1994
29
MidWestOne Bankmidwestone.bank

A community bank offering personal banking, small business banking, wealth management, mortgage services, and more in multiple states(Member FDIC)

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Iowa City 734 1934
30
Bankers Trustbankerstrust.com

A leading financial institution offering commercial and consumer banking services, innovative financial solutions, community support, and numerous awards for excellence

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 684 1917
31
Veridian Credit Unionveridiancu.org

A financial cooperative in Iowa offering consumer financial services, with branches in Iowa, East Nebraska, and the Twin Cities metro area

Banking ๐Ÿ‡บ๐Ÿ‡ธ Waterloo 613 1934
32
SHAZAM Network - ITS, Inc.shazam.net

This company is a pioneer in PIN-debit transactions, offering payment processing and technology solutions for community banks and credit unions

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Johnston 581 1976
33
Central Bankmycentral.bank

Established in 1877, the company provides financial solutions, supports local organizations, and offers services such as banking, home loans, trust, and insurance

Banking ๐Ÿ‡บ๐Ÿ‡ธ Storm Lake 580 1877
34
Medical Associates Clinicmahealthcare.com

A leading multispecialty group practice clinic in Iowa providing superior healthcare with over 190 providers and various specialty services in multiple locations

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Dubuque 556 1924
35
Berkshire Hathaway Energybrkenergy.com

A sustainable energy company with a $1338 billion portfolio serving 12 million customers with low-cost, safe, and reliable service Headquarters in Iowa

Utilities ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 480 n/a
36
Lincoln Savings Bankmylsb.com

Established in 1902, we are a community bank dedicated to supporting local communities through charitable giving and personalized financial services

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Reinbeck 266 1902
37
Windstream

Provider of Unified Communications as a Service (UCaaS) solutions for businesses to streamline communication channels and enhance collaboration among teams

Telecommunications ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 263 1978
38
BHE Renewablesbherenewables.com

A renewable energy company with a large US portfolio focusing on generation from wind, water, solar, and geothermal sources Headquartered in Des Moines, Iowa

Renewable Energy Power Generation ๐Ÿ‡บ๐Ÿ‡ธ Des Moines 255 2011
39
LifeServe Blood Centerlifeservebloodcenter.org

A non-profit blood center serving hospitals in Iowa, Nebraska, and South Dakota, providing essential blood products and saving lives through volunteer donations

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Johnston 235 1947
40
Express Logistics, Inc.exp-logistics.com

Specializes in LTL, truckload, and intermodal freight solutions, focusing on efficient product transportation and strong client partnerships.

Truck Transportation ๐Ÿ‡บ๐Ÿ‡ธ Urbandale 217 2003
41
ImOn Communicationsimon.net

ImOn Communications provides data, voice, Internet, cable TV, and phone services to businesses and residents in Iowa, with a focus on advanced technology and local community support

Telecommunications ๐Ÿ‡บ๐Ÿ‡ธ Cedar Rapids 177 2007
42
MRHCmrhcia.com

A comprehensive healthcare center offering diagnostic radiology, emergency care, inpatient treatment, skilled nursing services, and a range of medical services in Manning

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Manning 134 n/a
43
First American Bank1934.bank

Privately owned community bank with locations in Iowa and southwest Florida offering personal and private banking services, mortgages, and FDIC insurance

Banking ๐Ÿ‡บ๐Ÿ‡ธ Fort Dodge 70 1934
44
R.I.A. Federal Credit Unionriafcu.com

A financial institution offering products and services to improve the financial well-being of its community, with a focus on customer satisfaction

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Bettendorf 64 1935
45
Ohnward Bank & Trustohnwardbank.bank

Locally owned bank providing innovative financial solutions for customers, supporting community growth, and offering equal employment opportunities

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Cascade 51 1903
46
South Story Bank & Trustsouthstorybank.com

A dedicated financial partner offering a wide range of services, including banking, loans, and financial management, to ensure clients' success

Banking ๐Ÿ‡บ๐Ÿ‡ธ Huxley 43 1954
47
AY Trucking LLCaytruckingllc.com

Specializing in full truckload, expedited, dedicated, and drop and hook dry van services to drive success in the transportation industry

Transportation, Logistics, Supply Chain and Storage ๐Ÿ‡บ๐Ÿ‡ธ Davenport 33 2021
48
Security Savings Bank South Dakotabankwithssb.com

Established in 1920, the company offers a range of financial services including business banking, personal banking, wealth management, and insurance solutions

Banking ๐Ÿ‡บ๐Ÿ‡ธ Larchwood 21 n/a
49
Farmers State Bank of Yalesecure.yalebankiowa.com

A longstanding financial institution offering a range of banking services including accounts, CDs, IRAs, loans, with a focus on community support and growth

Banking ๐Ÿ‡บ๐Ÿ‡ธ Yale 14 1921
50
First Trust and Savings Bank (Coralville, IA)ft-sb.com

Providing top-notch banking services with a personalized touch to customers in their local communities and around the globe

Banking ๐Ÿ‡บ๐Ÿ‡ธ Coralville 1 1931

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

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