This selection of companies in Missouri includes large corporate groups. Many operate in services, such as Ascension and Express Scripts Pharmacy Benefit Services in healthcare, Panera Bread in restaurants, and Enterprise in car rental. Other notable companies include Advantage Solutions, which provides outsourced sales and marketing services, and Hallmark Cards, a global business creating greeting cards and gifts.
The headquarters are primarily concentrated in St. Louis, which hosts companies like Caleres, Inc., a global footwear brand portfolio, and Energizer Holdings, a global organization creating innovative products. Kansas City also features prominently with companies such as H&R Block, providing tax preparation services worldwide, and Hallmark Cards. This indicates a strong presence of established firms across diverse service and manufacturing sectors.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Ascensionhealthcare.ascension.org
A faith-based healthcare organization focused on providing compassionate care to those in need across the US through various services and programs |
66,381 | |||
| 2 |
Panera Breadpanerabread.com
Fresh bakery foodservice offering freshly baked breads, pastries, and clean food with omni-channel ordering and community focus. |
39,768 | |||
| 3 |
Enterpriseenterprisemobility.com
Provides car rental services globally through multiple brands, offering employment opportunities and vehicle access in many countries. |
32,638 | |||
| 4 |
Advantage Solutionsyouradv.com
Provider of outsourced sales and marketing services including retail merchandising, digital commerce, sampling, and omnichannel marketing for consumer goods companies. |
27,762 | |||
| 5 |
Wal Mart Corporation
This company provides access to Walmart executive speeches, financial reports, press releases, photos, videos, and interactive global location map |
19,478 | |||
| 6 |
Hallmark Cardscareers.hallmark.com
Family-owned global business creating emotionally connected world through greeting cards, gifts, media networks, real estate development, and art products for children worldwide |
17,388 | |||
| 7 |
H&R Blockhrblock.com
H&R Block provides tax preparation services worldwide, focusing on building long-lasting relationships through care, innovation, and a people-first approach |
16,116 | |||
| 8 |
Express Scripts Pharmacy Benefit Servicesevernorth.com
Creation and management of prescription benefit programs aimed at reducing costs for members, health plans, employers, and agencies. |
12,361 | |||
| 9 |
Bass Pro Shopsbasspro.com
Premier outdoor and conservation company offering destination retail, boats, resorts, and nature experiences, all while promoting conservation and community impact |
10,126 | |||
| 10 |
Caleres, Inc.jobs.caleres.com
This company is a global footwear brand portfolio with diverse offerings, including famous labels like Sam Edelman and Naturalizer, focusing on consumer-driven innovation and quality craftsmanship |
9,313 | |||
| 11 |
Energizer Holdingsenergizerholdings.com
A global organization creating innovative products to improve lives, focused on serving customers, driving revenue, and delivering long-term value |
6,098 | |||
| 12 |
Leggett & Plattleggett.com
Designing and manufacturing innovative products and components for bedding, furniture, seating, homes, offices, airplanes, and automobiles worldwide. |
4,601 | |||
| 13 |
Shelter Insurance Companiesshelterinsurance.com
Property and casualty insurance provider offering auto, home, life, renters, farm, business, and specialty insurance products across multiple states. |
4,253 | |||
| 14 | 3,682 | ||||
| 15 |
Maritzmaritz.com
A behavioral science-driven company solving business challenges for Fortune 500 clients through research, incentives, rewards, experience design, and events services and solutions |
3,349 | |||
| 16 |
National Beef Packing Company LLCnationalbeef.com
Processing and marketing fresh beef, consumer-ready products, beef by-products, leather, and providing transportation and logistical services across multiple U.S. locations. |
1,757 | |||
| 17 |
Spring Venture Groupspringventuregroup.com
A holding company specializing in direct-to-consumer health insurance brands for the 65+ market, using analytics and technology to provide a personalized shopping experience |
1,370 | |||
| 18 |
Herzogherzog.com
A leading industry expert in railroad construction, maintenance, and operations with in-house equipment design for data-driven operational decisions |
1,356 | |||
| 19 | 1,316 | ||||
| 20 |
Colibri Groupcolibrigroup.com
This company provides professional education solutions for licensing, continuing education, test preparation, and career readiness, helping individuals excel in their careers |
1,276 | |||
| 21 |
Kansas City Southernkcsouthern.com
Transportation holding company with railroad investments in the U.S., Mexico, and Panama, linking major commercial and industrial centers. |
1,147 | |||
| 22 |
Arch Resources, Inccorenaturalresources.com
Producer and exporter of metallurgical and thermal coals, operating multiple mines and marine export terminals focused on seaborne markets. |
1,136 | |||
| 23 |
ArchKey Solutionsarchkey.com
A leading specialty trade installation and facilities services company with expertise in electrical, technologies, and specialty systems for new and existing facilities |
1,100 | |||
| 24 |
Focus Financial Partnersfocusfinancialpartners.com
Leading partnership of independent wealth management firms providing best practices, resources, and continuity planning to serve individuals, families, employers, and institutions |
1,028 | |||
| 25 |
Alberici Constructorsalberici.com
Diversified construction company delivering complex projects across North America with quality, integrity, and a focus on employee expertise and client satisfaction. |
1,002 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 26 |
UniGroupunigroup.com
Transportation company providing corporate moving services through leading van lines, logistics solutions, transportation management, and supplies for professional interstate moves |
975 | |||
| 27 |
Cass Information Systemscassinfo.com
Provider of integrated information and payment management solutions for supply chains, communications, facilities, and operations, disbursing over $90 billion annually |
870 | |||
| 28 |
News-Press & Gazette Companynpgco.com
A multi-generational company based in St Joseph, Missouri, with holdings in broadcast television, newspapers, and other media and technology investments |
780 | |||
| 29 |
Electric Power Systemsasplundhpower.com
An independent electrical testing & engineering organization specializing in commissioning, start up, and maintenance testing for various facilities globally |
741 | |||
| 30 |
TKC Holdings, Inc.careers.tkcholdings.com
A leading provider of food service and product delivery, specializing in delivering quality services with integrity and innovation while supporting career development |
727 | |||
| 31 |
Capacitycapacity.com
This company offers a support automation platform using AI to deflect tickets, emails, and calls, helping teams streamline their processes |
707 | |||
| 32 |
International Financial Data Services (IFDS)ssctech.com
Provider of financial data management and administration services, supporting investment funds and financial institutions with technology-driven solutions. |
689 | |||
| 33 |
U.S. Engineeringusengineering.com
Full-service company providing award-winning plumbing, piping, HVAC, and sheet metal construction, service, and maintenance for various industries including healthcare, government, and commercial sectors |
688 | |||
| 34 |
American Industrial Transport - AITXaitx.com
A leading railcar service provider offering leasing, repair, and railcar data solutions, with a diverse leasing fleet, best-in-class repair network, and financing options |
684 | |||
| 35 |
Americo Financial Life and Annuityamerico.com
Provides a comprehensive range of life insurance and annuity products focused on customer needs and agent support with strong management. |
622 | |||
| 36 |
Missouri Farm Bureaumofbinsurance.com
A multi-line insurance company in Missouri providing auto, home, life, and business insurance products with top ratings for security |
606 | |||
| 37 |
Cogentcogentcompanies.com
Twelve partner companies providing fluid pumping and water processing solutions for industrial, municipal, commercial building trades, and oil and gas market sectors. |
578 | |||
| 38 |
MFA Oil Companymfaoil.com
A farmer-owned cooperative supplying fuels, lubricants & propane in multiple states, also operating convenience stores and tire franchises Visit website for more |
572 | |||
| 39 |
CCA Global Partnersccaglobalpartners.com
Empowering entrepreneurs with scale, resources, and innovation in various industries, fostering sustainability, growth, and effective competition in the marketplace |
560 | |||
| 40 |
Tepa Companiestepa.com
A shared services organization providing leadership and management to various small businesses, offering construction, engineering, environmental, industrial, and technology services |
552 | |||
| 41 |
Flat Branch Home Loansflatbranchhomeloans.com
A company offering low rate mortgages in 30 states with exceptional service, expert staff, and assistance for home purchases or refinancing |
535 | |||
| 42 |
Benjamin F. Edwardsbenjaminfedwards.com
National wealth management firm offering full-service brokerage and independent advisory services, prioritizing clients' interests with personalized solutions for advisors and clients |
524 | |||
| 43 |
Safe Fleetsafefleet.net
The company offers integrated safety solutions for fleets, prioritizing safety through advanced technology to prevent accidents and ensure driver and passenger well-being |
507 | |||
| 44 |
Independent Stave Companyindependentstavecompany.com
Global cooperage company with facilities around the world, producing wine and whiskey barrels for customers in over 40 countries |
486 | |||
| 45 |
Marmic Fire & Safety Co.marmicfire.com
A full-service safety company specializing in fire protection services, including fire extinguishers, fire suppression systems, and equipment installation, inspection, and repair |
458 | |||
| 46 |
McCormack Baron Companiesmccormackbaron.com
The company specializes in developing, building, and managing economically-integrated urban neighborhoods by providing high-quality housing and community development services |
417 | |||
| 47 |
Tetrasoft Inc.tetrasoft.us
A global digital services company specializing in innovative solutions for industries such as healthcare, insurance, and manufacturing using disruptive technologies and strategies |
416 | |||
| 48 |
SCFingrammarinegroup.com
The company provides integrated river transportation, logistics services, operates fleet of barges and towboats, inland terminals, warehouses, and invests in infrastructure projects |
386 | |||
| 49 |
BW Packagingbwpackaging.com
Global supplier of packaging machinery and solutions including filling, closing, labeling, flexible packaging, end-of-line systems, and integration services. |
344 | |||
| 50 |
ArchKey Solutions/Sachs Electricarchkey.com
A leading specialty trade installation and facilities services provider, offering design, construction, and maintenance of electrical, technology, and specialty systems nationwide |
319 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Missouri
- The largest companies in Missouri 1,495
- Multinational companies in Missouri 201
- Manufacturers in Missouri 162
- Retail chains in Missouri 143
- Education providers in Missouri 130
- Critical infrastructure operators in Missouri 120
- Healthcare providers in Missouri 118
- Hospitals and Health Care companies in Missouri 118
- Financial services firms in Missouri 116
- Companies with in-house R&D in Missouri 96
- Family-owned companies in Missouri 84
- Professional services firms in Missouri 84
- Companies with a mobile app in Missouri 78
- Public sector organisations in Missouri 78
- Construction companies in Missouri 72
- Higher Education companies in Missouri 70
- IT Services and IT Consulting companies in Missouri 69
- Hardware manufacturers in Missouri 68
- IT services companies in Missouri 61
- Distributors and wholesalers in Missouri 57
- Financial Services companies in Missouri 53
- Logistics companies in Missouri 46
- Consulting firms in Missouri 43
- Contract manufacturers in Missouri 43
The same list elsewhere in United States
- Corporate groups and holding companies in the United States 2,829
- Corporate groups and holding companies in California 270
- Corporate groups and holding companies in New York State 245
- Corporate groups and holding companies in Texas 238
- Corporate groups and holding companies in Florida 182
- Corporate groups and holding companies in Illinois 154
- Corporate groups and holding companies in Pennsylvania 120
- Corporate groups and holding companies in Ohio 104
- Corporate groups and holding companies in Georgia 90
- Corporate groups and holding companies in Michigan 90
- Corporate groups and holding companies in Alabama 89
- Corporate groups and holding companies in Massachusetts 87
- Corporate groups and holding companies in New Jersey 79
- Corporate groups and holding companies in Virginia 78
- Corporate groups and holding companies in North Carolina 70
- Corporate groups and holding companies in Tennessee 60
- Corporate groups and holding companies in Wisconsin 60
- Corporate groups and holding companies in Minnesota 57
- Corporate groups and holding companies in Indiana 54
- Corporate groups and holding companies in Colorado 52
- Corporate groups and holding companies in New York 152
- Corporate groups and holding companies in Houston 74
- Corporate groups and holding companies in Chicago 64
- Corporate groups and holding companies in Atlanta 47