The chemical companies listed here are primarily large and mid-sized firms, with a strong presence in the St. Louis area. Many specialize in manufacturing and industrial applications. Monsanto Company is notable for its agricultural focus, while Olin manufactures a broad range of chemical products. Carboline specializes in high-performance coatings, and MLC is a major supplier of lime products. Hillyard, Inc. produces cleaning solutions, and ZOLTEK focuses on carbon fiber technology.
A significant concentration of these companies, including Monsanto, Carboline, MLC, and ZOLTEK, are headquartered in St. Louis. This indicates a geographical cluster for chemical manufacturing and related industries within Missouri. Several companies, such as Olin and Hillyard, Inc., were founded in the late 19th or early 20th century, suggesting a long-established industrial base.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Monsanto Companybayer.com
Leading in modern agriculture with a focus on seeds, plant traits, and crop protection through innovative breakthroughs for global impact |
9,303 | |||
| 2 | 3,682 | ||||
| 3 | 1,010 | ||||
| 4 |
Hillyard, Inc.hillyard.com
A leading manufacturer and distributor of cleaning solutions, dedicated to helping customers achieve clean, safe, and healthy facilities at the lowest cost |
744 | |||
| 5 |
ZOLTEKzoltek.com
Specializing in carbon fiber technology, the company leads in commercializing carbon fiber as a primary composite building material for various industries |
736 | |||
| 6 |
Precoat Metalsprecoat.com
Leading coil coating supplier in North America with 3 million tons of capacity, offering dedicated lines, technical support, in-house processing, and multiple metal sourcing options |
630 | |||
| 7 |
MECSmecsglobal.com
Global leader in sulfuric acid process technology and high performance products for acid plant production, with expertise in ethanol production and air pollution control |
617 | |||
| 8 |
The Gund Companythegundcompany.com
Custom engineered material solutions provider, manufacturing and fabricating parts worldwide. Material specialists offer consultative services, optimizing production for efficiency and cost reduction. |
505 | |||
| 9 |
Brewer Sciencebrewerscience.com
A global leader in developing innovative materials, processes, and equipment for cutting-edge microdevices used in electronics, specializing in advanced lithography and nanotechnology |
447 | |||
| 10 |
Schaeffer Mfg. Companyschaefferoil.com
Family-owned company delivering specialized lubricant solutions for equipment challenges, enhancing engine durability, fuel economy, and overall equipment efficiency for customers. |
431 | |||
| 11 |
American Plasticsamericanplasticsllc.com
Manufacturer of injection molded storage solutions including resin shelving, tool boxes, and cleaning products for household and garage organization via national retailers. |
417 | |||
| 12 |
Alpha Packagingalphap.com
Manufacturer of plastic bottles and jars for various industries worldwide, offering stock and custom PET and HDPE containers in sizes up to 1 gallon |
411 | |||
| 13 |
Spartech LLCspartech.com
Develops custom engineered plastic sheet and rollstock solutions for diverse industries, offering various materials, specializing in thermoforming, medical, military, and packaging applications. |
407 | |||
| 14 |
Tnemec Company, Inc.tnemec.com
Manufacturer of over 100 architectural and industrial coatings, including premium epoxies and polyurethanes, specializing in durability, performance, and aesthetics with a global reputation for quality and leading technology |
316 | |||
| 15 |
SAFCsigma-aldrich.com
Manufacturing specialty chemicals, biologics, high-purity inorganic materials, critical raw materials, and high-potent APIs for life science and high-technology industries |
297 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
FutureFuel Chemical Companyfuturefuelcorporation.com
A leader in custom toll manufacturing of specialty chemicals and biodiesel, offering services from process analysis to full-scale production with sustainability focus |
277 | |||
| 17 |
ICL U.S.icl-group.com
A leading global specialty minerals company focused on sustainable solutions in food, agriculture, and industrial markets through R&D and innovation |
274 | |||
| 18 |
Jost Chemicaljostchemical.com
Manufactures high-purity inorganic specialty chemicals and minerals for pharmaceutical, biotech, nutritional, and food markets, including process intermediates and mineral supplements. |
271 | |||
| 19 |
Aegion Corporationazuria.com
A global leader in water infrastructure solutions, specializing in strengthening, rehabilitating, and maintaining aging water systems around the world since 1971 |
199 | |||
| 20 |
Conklin Company, Incconklin.com
A manufacturing and distribution company with 40 years of experience, offering over 130 quality products across various sectors through Independent Business Owners |
197 | |||
| 21 |
IPL North Americaipl-plastics.com
Leading manufacturer of injection-molded plastic products for food packaging, environment, and material handling sectors since 1939, providing custom solutions for competitiveness and productivity |
190 | |||
| 22 |
Gruppo Ceramiche Gresmaltgresmalt.it
Dynamic Italian group leading in ceramic industry, investing in innovative technologies to produce high-performance materials With 4 brands, global distribution, and sustainable headquarters |
188 | |||
| 23 |
Koller Craftkoller-craft.com
Family-owned full service provider of injection molded plastic components with expertise in various industries, offering engineering support and high-quality products |
51 | |||
| 24 |
VECTRAvectraco.com
A technology-based industrial growth company developing materials and technologies for global applications in energy storage, electronics, renewable energy, and automotive systems |
44 | |||
| 25 |
MO SCImo-sci.com
A world leader in precision glass technology, specializing in glass microspheres, fibers, and frit for healthcare and specialty applications Located in Missouri, USA |
40 | |||
| 26 |
Missouri Petroleum Products Co., LLCmissouripetroleum.com
Leading manufacturer and applicator of asphalt-based surface treatments in Eastern Missouri, offering a wide range of quality products and professional installation services for pavement maintenance needs |
30 | |||
| 27 |
PAN COMPOSITIpancompositi.com
Specializing in manufacturing composite parts, carbon molds, tools, carbon look components, and structural composite parts for various industries and applications |
21 | |||
| 28 |
Insulite Glass Co Incinsuliteglass.com
Glass, ceramics & concrete company located in Saint Louis, Missouri, specializing in insulating glass products for residential and commercial applications |
20 | |||
| 29 |
Seiler Plasticsseilerpc.com
Custom plastic extrusion and injection mold manufacturer specializing in producing custom plastic parts including tubing, profiles, and sheet in small or large quantities |
14 | |||
| 30 | 
Pro Plas Incproplasinc.com
Specializing in custom injection molding, offering tooling design, build, and maintenance services Experienced in molding custom and engineering resins with full production and assembly capabilities |
4 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
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The same list elsewhere in United States
- Chemical companies in the United States 1,383
- Chemical companies in Texas 140
- Chemical companies in Ohio 120
- Chemical companies in California 112
- Chemical companies in Pennsylvania 95
- Chemical companies in Illinois 74
- Chemical companies in New York State 61
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- Chemical companies in North Carolina 54
- Chemical companies in Georgia 51
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- Chemical companies in Indiana 34
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