This list features companies with in-house R&D based in Minneapolis, predominantly large and mid-sized firms. The selection includes companies like Medtronic, a healthcare technology company, and General Mills, which produces food products. Other notable firms are Xcel Energy, providing energy services, and The Toro Company, which offers equipment and solutions for various outdoor industries.
The companies here represent a mix of established sectors, with a strong presence in manufacturing, particularly medical equipment and industrial machinery. There is also a significant cluster of firms founded in the early to mid-20th century, such as General Mills (1928), Graco (1926), and Daikin Applied Americas (1924).
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Medtronicmedtronic.com
A healthcare technology company tackling challenging health issues worldwide with innovative solutions that significantly impact and improve lives |
100,323 | |||
| 2 |
General Millsgeneralmills.com
The company is dedicated to creating beloved food products while prioritizing positive impact, learning, innovation, and growth through collaboration and leadership |
25,309 | |||
| 3 |
Xcel Energyxcelenergy.com
providing reliable, resilient, and sustainable energy services to customers across eight states, focusing on excellent service and growth opportunities |
12,073 | |||
| 4 |
The Toro Companythetorocompany.com
Portfolio of global brands providing innovative equipment and solutions for landscaping, construction, irrigation, and outdoor maintenance industries worldwide. |
6,275 | |||
| 5 | 4,942 | ||||
| 6 |
Daikin Applied Americasdaikinapplied.com
Provides advanced HVAC systems focusing on air quality, energy efficiency, IoT integration, and next-generation compressors through global sales and service network. |
4,833 | |||
| 7 |
Entrustentrust.com
Provides identity-centric security solutions, protecting people, devices, data. Fights fraud, cyber threats, secures identity lifecycle, ensures transaction confidence. Global presence, 150 countries. |
3,755 | |||
| 8 |
Sleep Number Corporationsleepnumber.com
Company improves health and wellbeing through innovative sleep products, operating retail stores, distribution centers, and supporting diverse workforce nationwide. |
3,632 | |||
| 9 |
Bio-Technebio-techne.com
A leading developer and manufacturer of high-quality purified proteins, reagent solutions, diagnostic products, and genomic tools for research and clinical use globally |
2,924 | |||
| 10 | 2,382 | ||||
| 11 |
Perforce Softwareperforce.com
Leader in digital product development, providing innovative solutions for faster and higher quality output through the power of Perforce technology |
2,028 | |||
| 12 |
HealthEastfairview.org
A leading nonprofit healthcare provider in Minnesota offering a full range of services including hospitals, clinics, senior care, rehabilitation, and home health services with compassion |
1,830 | |||
| 13 |
Federal Reserve Bank of Minneapolisminneapolisfed.org
Support national monetary and financial system stability, uphold ethical standards, embrace diversity, and provide development opportunities for workforce excellence. |
1,047 | |||
| 14 |
University of Minnesota College of Science and Engineeringcse.umn.edu
The organization is the UMN College of Science and Engineering, part of the University of Minnesota, focusing on education and research |
582 | |||
| 15 |
University of Minnesota School of Public Healthsph.umn.edu
Top public health school dedicated to researching and solving serious health issues, supporting alumni, students, faculty, and community in improving lives |
431 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 | 387 | ||||
| 17 |
Flagstone Foodsflagstonefoods.com
Flagstone Foods is a leading private label snacking company in North America, specializing in healthy snacks like nuts, trail mixes, and dried fruits |
373 | |||
| 18 |
Minco Products, Incminco.com
provides advanced engineered solutions combining product technologies, design, and engineering for medical, aerospace, defense, and high-reliability applications worldwide |
334 | |||
| 19 |
Apogee Enterprises, Inc.apog.com
Design and manufacture glass and aluminum window, storefront, curtainwall systems, and protective glass products for buildings and framing markets. |
286 | |||
| 20 |
Kurt Manufacturingkurt.com
We are a driven, innovative company that strives to exceed industry standards and deliver quality products with precision, passion, and loyalty |
279 | |||
| 21 |
CVRx | Barostimcvrx.com
A medical devices company in Minneapolis, MN, using proprietary implantable technology to treat high blood pressure and heart failure |
255 | |||
| 22 |
AWT Labels & Packagingawtlabelpack.com
A leader in innovative and sustainable solutions for labeling, packaging, and converting, servicing Healthcare, Consumer Brands, and Technology clients worldwide |
217 | |||
| 23 |
University of Minnesota College of Designdesign.umn.edu
The College of Design in the Twin Cities offers education, research, and innovation in various design disciplines with a focus on creativity and advancing technologies |
216 | |||
| 24 |
ProteinSimple, a Bio-Techne brandbio-techne.com
Leader in rethinking protein tools with a wide-ranging portfolio including immunoassay and structural analysis systems to help researchers gain new insights into proteins and diseases |
183 | |||
| 25 |
Resolution Medicalresolutionmedical.com
A company providing innovative business solutions to the medical device industry, focusing on high quality, exceptional customer service, and continuous life improvement |
179 | |||
| 26 |
Apothecary Productsapothecary-brands.com
A consumer products company founded in 1975, focused on self-care and wellness solutions with innovative brands, international presence, and patented products |
135 | |||
| 27 |
Omnetics Connector Corporationomnetics.com
Design and manufacture micro-miniature and nano-miniature high-reliability electronic connectors and interconnection systems for military, aerospace, medical, and high-tech OEMs. |
128 | |||
| 28 |
AMETEK Paragon Medicalparagonmedical.com
A global leader in medical technology design and manufacturing, offering state-of-the-art solutions for clinical applications through custom interconnects, catheter components, and precision laser machining services |
117 | |||
| 29 |
Nidec America Corporation
An electrical and electronic manufacturing company headquartered in Minneapolis, specializing in producing a wide range of products |
50 | |||
| 30 |
Decca Contract Furnituredeccacontract.com
A luxury furniture manufacturer specializing in high-quality, custom cabinetry with a commitment to sustainability and responsible business practices |
18 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
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The same list elsewhere in United States
- Companies with in-house R&D in the United States 6,796
- Companies with in-house R&D in California 1,275
- Companies with in-house R&D in Texas 442
- Companies with in-house R&D in New York State 419
- Companies with in-house R&D in Massachusetts 396
- Companies with in-house R&D in Illinois 322
- Companies with in-house R&D in Michigan 287
- Companies with in-house R&D in Ohio 277
- Companies with in-house R&D in Pennsylvania 255
- Companies with in-house R&D in New Jersey 224
- Companies with in-house R&D in Florida 221
- Companies with in-house R&D in Alabama 215
- Companies with in-house R&D in Georgia 173
- Companies with in-house R&D in Virginia 166
- Companies with in-house R&D in North Carolina 158
- Companies with in-house R&D in Wisconsin 154
- Companies with in-house R&D in Minnesota 146
- Companies with in-house R&D in Washington State 140
- Companies with in-house R&D in Colorado 113
- Companies with in-house R&D in Maryland 107
- Companies with in-house R&D in Indiana 104
- Companies with in-house R&D in New York 223
- Companies with in-house R&D in San Francisco 147
- Companies with in-house R&D in Houston 129