These Pittsburgh-based companies with in-house R&D span a range of industries, with a notable presence in healthcare, manufacturing, and transportation. They include large established organizations like UPMC, a major healthcare provider and insurer, and PPG, which develops paints, coatings, and specialty materials. Wabtec Corporation provides equipment and digital solutions for freight rail and transit, while the University of Pittsburgh is a top-ranked public research institution.
The list also features Viatris, a global healthcare company with an extensive medicine portfolio, and Howmet Aerospace, a provider of advanced engineered solutions for aerospace. A common pattern observed is the significant representation of companies with long histories, such as PPG, founded in 1883, and Wabtec, established in 1869, indicating a strong foundation of traditional industries in the region.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 | 41,860 | ||||
| 2 | 33,277 | ||||
| 3 |
Wabtec Corporationwabteccorp.com
Provider of equipment, systems, digital solutions, and services for freight rail, transit, mining, industrial, and marine transportation sectors. |
27,000 | |||
| 4 |
University of Pittsburghpitt.edu
Top-ranked public institution in Pennsylvania, member of leading research universities Known for innovative discoveries and shaping future paths |
19,349 | |||
| 5 |
Viatrisviatris.com
Global healthcare company providing extensive medicine portfolio and supply chain to deliver high-quality medicines addressing diverse health needs worldwide. |
17,886 | |||
| 6 |
Allegheny Health Networkahn.org
Integrated healthcare delivery system with hospitals, medical centers, wellness pavilions, and numerous physician practices serving Western Pennsylvania. |
11,676 | |||
| 7 |
Howmet Aerospacehowmet.com
A global provider of advanced engineered solutions for aerospace and transportation industries, specializing in jet engine components, aerospace fastening systems, and titanium structural parts |
7,402 | |||
| 8 |
United States Steel Corporationussteel.com
Developing and delivering profitable, next-generation steel solutions focused on safety and meeting current and future customer needs. |
6,794 | |||
| 9 |
Kennametalkennametal.com
A global industrial technology leader specializing in advanced materials innovation, tooling, and wear-resistant solutions to enhance productivity for various industries |
6,659 | |||
| 10 |
Arconicarconic.com
A leading provider of aluminum products for automotive, aerospace, transportation, industrial, packaging, and construction markets, committed to innovation and advancement |
4,672 | |||
| 11 |
UPMC Children's Hospital of Pittsburghchp.edu
A leader in treating childhood conditions, developing therapies, educating pediatricians, and advancing research with strong community support since 1890 |
3,489 | |||
| 12 |
Excelitas Technologies Corp.excelitas.com
Provider of advanced photonic technologies specializing in sensing, detection, imaging, optics, and specialty illumination for diverse global industries. |
3,129 | |||
| 13 |
Auroraaurora.tech
Aurora provides self-driving technology for transportation, making it safer, more accessible, and efficient for various vehicle types and industries |
2,568 | |||
| 14 |
Matthews Internationalmatw.com
Global provider of precision industrial technologies and memorialization products, serving industries and funeral homes with innovative, efficient solutions. |
2,226 | |||
| 15 |
University of Pittsburgh School of Medicinemedschool.pitt.edu
Training physician leaders and scientists to improve health, advance research, promote equity, and collaborate internationally in medicine and education. |
2,199 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
Industrial Coatingsppg.com
Global provider of advanced coatings, paints, and specialty materials focused on protecting and enhancing industrial products and landmarks. |
1,830 | |||
| 17 |
Koppers Inc.koppers.com
A global wood preservation technology company creating environmentally responsible solutions for various industries, with a focus on safety and sustainability |
1,080 | |||
| 18 |
Software Engineering Institute | Carnegie Mellon Universitysei.cmu.edu
The company conducts research on software engineering, cybersecurity, and AI, creating and testing innovative technologies for government and private industry since 1984 |
1,061 | |||
| 19 |
Talogytalogy.com
Experts in talent management crafting solutions for screening, selecting, developing, and engaging talent worldwide using psychology and technology for data-driven decisions |
1,036 | |||
| 20 | 1,028 | ||||
| 21 |
HarbisonWalker Internationalthinkhwi.com
A global leader in refractory products delivering solutions to industries worldwide with over 150 years of excellence in performance and value |
809 | |||
| 22 |
Carnegie Learningcarnegielearning.com
Innovative K-12 education technology company providing curriculum, professional learning, and tutoring solutions to support deep understanding and real-world applications |
782 | |||
| 23 |
Aerotech, Inc.aerotech.com
This company specializes in designing and manufacturing precision motion control systems for various industries and research institutions worldwide |
760 | |||
| 24 |
Industrial Scientificindsci.com
Innovative company designs gas detection products to protect workers globally, pioneering technologies for detecting and responding to hazardous conditions in real time |
755 | |||
| 25 |
LB Fosterlbfoster.com
A leading provider of materials for transportation, construction, recreation, and agriculture projects, offering engineering, manufacturing, distribution, and service solutions globally |
692 | |||
| 26 |
Latitude AIlat.ai
A subsidiary of Ford Motor Company developing automated driving technologies to create safer, less stressful, and more enjoyable driving experiences |
604 | |||
| 27 |
Upmc Passavantupmc.com
A $23 billion nonprofit health enterprise with 92,000 employees, 40 hospitals, and over 8,000 licensed beds, providing global integrated healthcare services |
590 | |||
| 28 |
Pittsburgh Glass Worksvitro.com
Global leader in OEM automotive glass manufacturing with 13 locations in US, Canada, and Poland, emphasizing innovation and growth through recent acquisitions and advancements |
513 | |||
| 29 |
University of Pittsburgh Swanson School of Engineeringengineering.pitt.edu
A top-ranked engineering program focusing on research in sustainability, energy systems, bioengineering, computational modeling, and advanced materials and manufacturing |
351 | |||
| 30 |
Gecko Roboticsgeckorobotics.com
The company provides complete solutions using wall-climbing robots, sensors, and AI to ensure the availability, reliability, and sustainability of critical infrastructure |
323 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
More company lists in Pittsburgh
- The largest companies in Pittsburgh 381
- Multinational companies in Pittsburgh 55
- Education providers in Pittsburgh 42
- Manufacturers in Pittsburgh 33
- Financial services firms in Pittsburgh 32
- Professional services firms in Pittsburgh 32
- Hospitals and Health Care companies in Pittsburgh 26
- Critical infrastructure operators in Pittsburgh 25
The same list elsewhere in United States
- Companies with in-house R&D in the United States 6,796
- Companies with in-house R&D in California 1,275
- Companies with in-house R&D in Texas 442
- Companies with in-house R&D in New York State 419
- Companies with in-house R&D in Massachusetts 396
- Companies with in-house R&D in Illinois 322
- Companies with in-house R&D in Michigan 287
- Companies with in-house R&D in Ohio 277
- Companies with in-house R&D in Pennsylvania 255
- Companies with in-house R&D in New Jersey 224
- Companies with in-house R&D in Florida 221
- Companies with in-house R&D in Alabama 215
- Companies with in-house R&D in Georgia 173
- Companies with in-house R&D in Virginia 166
- Companies with in-house R&D in North Carolina 158
- Companies with in-house R&D in Wisconsin 154
- Companies with in-house R&D in Minnesota 146
- Companies with in-house R&D in Washington State 140
- Companies with in-house R&D in Colorado 113
- Companies with in-house R&D in Maryland 107
- Companies with in-house R&D in Indiana 104
- Companies with in-house R&D in New York 223
- Companies with in-house R&D in San Francisco 147
- Companies with in-house R&D in Houston 129